Results 31 to 40 of about 29,066 (192)

The course of COVID-19 in a 55-year-old patient diagnosed with severe idiopathic pulmonary arterial hypertension

Pulmonary Circulation, 2020
We describe a 55-year-old woman with severe idiopathic pulmonary arterial hypertension (mean pulmonary artery pressure 71 mmHg, pulmonary vascular resistance 30 WU at diagnosis five months ago), who was diagnosed with SARS-CoV-2 infection (COVID-19) and ...
Diana Mandler, Mona Lichtblau, Silvia Ulrich   +2 more
doaj   +1 more source

Application of [18F]FLT‐PET in pulmonary arterial hypertension: a clinical study in pulmonary arterial hypertension patients and unaffected bone morphogenetic protein receptor type 2 mutation carriers

Pulmonary Circulation, 2021
Pulmonary arterial hypertension is a heterogeneous group of diseases characterized by vascular cell proliferation leading to pulmonary vascular remodelling and ultimately right heart failure. Previous data indicated that 3′‐deoxy‐3′‐[18F]‐fluorothymidine
Liza Botros, Samara M.A. Jansen, Ali Ashek, Onno A. Spruijt, Jelco Tramper, Anton Vonk Noordegraaf, Jurjan Aman, Hans Harms, Frances S. deMan, Marc C. Huisman, Lan Zhao, Harm J. Bogaard   +11 more
doaj   +1 more source

Clinical heterogeneity of Pulmonary Arterial Hypertension associated with variants in TBX4.

PLoS ONE, 2020
BACKGROUND:The knowledge of hereditary predisposition has changed our understanding of Pulmonary Arterial Hypertension. Genetic testing has been widely extended and the application of Pulmonary Arterial Hypertension specific gene panels has allowed its ...
Ignacio Hernandez-Gonzalez, Jair Tenorio, Julian Palomino-Doza, Amaya Martinez Meñaca, Rafael Morales Ruiz, Mauro Lago-Docampo, María Valverde Gomez, Javier Gomez Roman, Ana Belén Enguita Valls, Carmen Perez-Olivares, Diana Valverde, Joan Gil Carbonell, Elvira Garrido-Lestache Rodríguez-Monte, Maria Jesus Del Cerro, Pablo Lapunzina, Pilar Escribano-Subias   +15 more
doaj   +1 more source

Platelet‐Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Platelet‐derived growth factor is a major regulator of the vascular remodeling associated with pulmonary arterial hypertension. We previously showed that protein widely 1 (PW1+) vascular progenitor cells participate in early vessel ...
Julien Solinc, Jessica Raimbault‐Machado, France Dierick, Lamiaa El Bernoussi, Ly Tu, Raphaël Thuillet, Nathalie Mougenot, Bénédicte Hoareau‐Coudert, Virginie Monceau, Catherine Pavoine, Fabrice Atassi, David Sassoon, Giovanna Marazzi, Richard P. Harvey, Peter Schofield, Daniel Christ, Marc Humbert, Christophe Guignabert, Florent Soubrier, Sophie Nadaud   +19 more
doaj   +1 more source

Nocturnal hypoxia in patients with idiopathic pulmonary arterial hypertension [PDF]

Pulmonary Circulation, 2020
BackgroundSleep‐disordered breathing causes a variety of cardiovascular complications and increases the risk of a poor prognosis in patients. There is still some controversy regarding the clinical diagnosis and treatment of sleep‐disordered breathing in patients with pulmonary hypertension.
Lu Yan, Qin Luo, Zhihui Zhao, Qing Zhao, Qi Jin, Yi Zhang, Zhihong Liu   +6 more
openaire   +4 more sources

“Nocturnal Seizures” in Idiopathic Pulmonary Arterial Hypertension [PDF]

Journal of Clinical Sleep Medicine, 2013
The usual differential diagnoses of nocturnal events in children include parasomnias, nocturnal seizures, nocturnal reflux (Sandifer syndrome), hypnic jerks, periodic limb movements of sleep, and sleep disordered breathing. We report a previously healthy young girl who presented to the sleep clinic for evaluation of nocturnal events which were ...
Anthony, Izzo, Julia, McSweeney, Thomas, Kulik, Umakanth, Khatwa, Sanjeev V, Kothare   +4 more
openaire   +2 more sources

A patient with severe idiopathic pulmonary arterial hypertension: Is there a way out? [PDF]

Терапевтический архив, 2017
The paper considers a clinical example of current therapy for idiopathic pulmonary arterial hypertension in a female patient with its clinical deterioration.
N A Tsareva, S N Avdeev, G V Neklyudova
doaj   +1 more source

CXCL13 in idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension [PDF]

Respiratory Research, 2016
Chemokine CXC ligand 13 (CXCL13) has been implicated in perivascular inflammation and pulmonary vascular remodeling in patients with idiopathic pulmonary artery hypertension (IPAH). We wondered whether CXCL13 may also play a role in chronic thromboembolic pulmonary hypertension (CTEPH) and whether serum levels of CXCL13 might serve as biomarkers in ...
Olsson, Karen M., Olle, Sandra, Fuge, Jan, Welte, Tobias, Hoeper, Marius M., Lerch, Christian, Maegel, Lavinia, Haller, Hermann, Jonigk, Danny, Schiffer, Lena   +9 more
openaire   +2 more sources

Multiple congenital visceral abnormalities as a rare cause of pulmonary arterial hypertension

The Egyptian Heart Journal, 2022
Background Pulmonary arterial hypertension (PAH) is a rare, progressive disorder. PAH is caused by a wide spectrum of pathologies but the cause remains undetermined on many occasions and patients are classified in the idiopathic group.
Parham Rabiee, Sedigheh Saedi
doaj   +1 more source

Identification and Functional Analysis of tRNA‐Derived Small RNAs in the Lung Tissues of Patients With Idiopathic Pulmonary Arterial Hypertension [PDF]

Pulm Circ
ABSTRACT Idiopathic pulmonary arterial hypertension (IPAH) is a pulmonary vascular disease with a poor prognosis. Its pathogenesis remains unclear and the treatment methods are limited. The expression of tRNA‐derived small RNA (tsRNA) in IPAH tissues remains unknown. tsRNA sequencing was conducted on lung tissue samples obtained from patients with IPAH
Chen Y, E Z, Zhou J, Ge F, Xu J, Ye S, Liang J, Ni B.   +7 more
europepmc   +2 more sources