Results 51 to 60 of about 47,637 (238)

CXCL13 in idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension [PDF]

Respiratory Research, 2016
Chemokine CXC ligand 13 (CXCL13) has been implicated in perivascular inflammation and pulmonary vascular remodeling in patients with idiopathic pulmonary artery hypertension (IPAH). We wondered whether CXCL13 may also play a role in chronic thromboembolic pulmonary hypertension (CTEPH) and whether serum levels of CXCL13 might serve as biomarkers in ...
Olsson, Karen M., Olle, Sandra, Fuge, Jan, Welte, Tobias, Hoeper, Marius M., Lerch, Christian, Maegel, Lavinia, Haller, Hermann, Jonigk, Danny, Schiffer, Lena   +9 more
openaire   +2 more sources

Multiple congenital visceral abnormalities as a rare cause of pulmonary arterial hypertension

The Egyptian Heart Journal, 2022
Background Pulmonary arterial hypertension (PAH) is a rare, progressive disorder. PAH is caused by a wide spectrum of pathologies but the cause remains undetermined on many occasions and patients are classified in the idiopathic group.
Parham Rabiee, Sedigheh Saedi
doaj   +1 more source

Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials. [PDF]

, 2014
BackgroundInhaled nitric oxide (INO), a selective pulmonary vasodilator, has revolutionized the treatment of neonatal hypoxemic respiratory failure (NHRF). However, there is lack of sustained improvement in 30 to 46% of infants.
Ambalavanan, Namasivayam, Bara, Rebecca, Cotten, C Michael, Das, Abhik, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, Garg, Meena, Higgins, Rosemary D, Keszler, Martin, Klein, Jonathan M, Lakshminrusimha, Satyan, Malian, Monica, Nelin, Leif D, Ohls, Robin, Saha, Shampa, Sanchez, Pablo J, Shankaran, Seetha, Sood, Beena G, Van Meurs, Krisa P, Wallace, Dennis   +18 more
core   +2 more sources

Idiopathic Pulmonary Arterial Hypertension Unmasked by Pregnancy

Acute Medicine Journal, 2020
A 31-year old woman presented to the acute medical unit 9 days post-partum with shortness of breath and peripheral oedema. Initially suspected to have either a pulmonary embolism or post-partum cardiomyopathy, she proceeded to have imaging including a CT Pulmonary angiogram and echocardiogram, which were suggestive of pulmonary hypertension and severe ...
A, Maxwell, T, Holman, T, Novak
openaire   +3 more sources

Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 [PDF]

, 2018
Sphingosine kinase 1 (SphK1) upregulation is associated with pathologic pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), but the mechanisms controlling its expression are undefined.
Chen, Jiwang, Comhair, Suzy, Machado, Roberto F., Natarajan, Viswanathan, Singla, Sunit, Sysol, Justin R., Zhao, Shuangping   +6 more
core   +1 more source

Human Herpesvirus 8 and Pulmonary Hypertension

Emerging Infectious Diseases, 2005
Human herpesvirus 8 (HHV-8) antibodies were detected in 1 of 33 patients with pulmonary hypertension (including in 1 of 16 with idiopathic pulmonary arterial hypertension), 5 of 29 with cystic fibrosis, and 3 of 13 with interstitial lung disease.
Emanuele Nicastri, Carmine Dario Vizza, Fabrizio Carletti, Stefania Cicalini, Roberto Badagliacca, Roberto Poscia, Giuseppe Ippolito, Francesco Fedele, Nicola Petrosillo   +8 more
doaj   +1 more source

The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]

, 2012
Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
core   +2 more sources

Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension

American Journal of Respiratory and Critical Care Medicine, 2021
Abstract Rationale Autoimmunity is believed to play a role in idiopathic pulmonary arterial hypertension (IPAH). It is not clear whether this is causative or a bystander of disease and if it carries any prognostic or treatment significance.
Jones R. J., De Bie E. M. D. D., Groves E., Zalewska K. I., Swietlik E. M., Treacy C. M., Martin J. M., Polwarth G., Li W., Guo J., Baxendale H. E., Coleman S., Savinykh N., Coghlan J. G., Corris P. A., Howard L. S., Johnson M. K., Church C., Kiely D. G., Lawrie A., Lordan J. L., Mackenzie Ross R. V., Zaba J. P., Wilkins M. R., Wort S. J., Fiorillo E., Orru V., Cucca F., Rhodes C. J., Graf S., Morrell N. W., McKinney E. F., Wallace C., Toshner M., Bleda M., Hadinnapola C., Haimel M., Auckland K., Tilly T., Martin J. M., Yates K., Treacy C. M., Day M., Greenhalgh A., Shipley D., Jubilee G., Irvine V., Kennedy F., Moledina S., MacDonald L., Tamvaki E., Barnes A., Cookson V., Chentouf L., Ali S., Othman S., Ranganathan L., Gibbs J. S. R., Gummadi M., DaCosta R., Pinguel J., Dormand N., Parker A., Stokes D., Ghedia D., Tan Y., Ngcozana T., Wanjiku I., Polwarth G., Cannon J., Sheares K. K., Taboda D., Mackenzie Ross R. V., Suntharalingam J., Grover M., Kirby A., Armstrong I., Trembath R.   +77 more
openaire   +4 more sources

Long-Term Survival in Idiopathic Pulmonary Arterial Hypertension Associated with Massive Pulmonary Artery Dilation

Canadian Respiratory Journal, 2011
The present report describes two patients with long-term survival after being diagnosed with idiopathic pulmonary arterial hypertension more than 20 years earlier.
Vanja Petrovic, Christopher J Ryerson, Robert D Levy   +2 more
doaj   +1 more source

Pulmonary Hypertension Registry: a single-center experience in Egypt

Egyptian Journal of Chest Disease and Tuberculosis, 2020
Introduction Pulmonary hypertension is a life-threatening progressive disease that eventually leads to disability and death. Aim To establish the first single-center registry for pulmonary hypertension in Egypt, Kasr Al-Ainy Hospitals, Cairo University ...
Youssef A Soliman, Reem Elkorashy, Eman Kamal, Mohamed S Ismail, Yasmine H El-Hinnawy, Hassan G Yamamah, Ahmed Abd El Aziz, Hussein Heshmat, Kareem Mahmoud, Hala El-Gunidy, Mostafa El Shazly, Medhat Soliman   +11 more
doaj   +1 more source