Results 71 to 80 of about 47,637 (238)

Hypoxemia during sleep and overnight rostral fluid shift in pulmonary arterial hypertension: a pilot study

open access: yesPulmonary Circulation, 2021
Sleep-related breathing disorders, including sleep apnea and hypoxemia during sleep, are common in pulmonary arterial hypertension, but the underlying mechanisms remain unknown.
Etienne-Marie Jutant   +9 more
doaj   +1 more source

Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension. [PDF]

open access: yes, 2019
Pulmonary arterial compliance (PAC), invasively assessed by the ratio of stroke volume to pulmonary arterial (PA) pulse pressure, is a sensitive marker of right ventricular (RV)-PA coupling that differs across the spectrum of pulmonary hypertension (PH ...
Bhattacharya, Priyanka T.   +15 more
core   +2 more sources

Epistatic interactions in idiopathic pulmonary arterial hypertension

open access: yesIndian Journal of Human Genetics, 2012
Idiopathic pulmonary arterial hypertension (IPAH) is a poorly understood complex disorder, which results in progressive remodeling of the pulmonary artery that ultimately leads to right ventricular failure. A two-hit hypothesis has been implicated in pathogenesis of IPAH, according to which the vascular abnormalities characteristic of PAH are triggered
Vadapalli, Shivani   +5 more
openaire   +3 more sources

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm   +2 more
wiley   +1 more source

Demographics and Outcomes of Pulmonary Hypertension Patients in United States Emergency Departments [PDF]

open access: yes, 2020
Introduction: Pulmonary hypertension (PH) is a common, yet under-diagnosed, contributor to morbidity and mortality. Our objective was to characterize the prevalence of PH among adult patients presenting to United States (US) emergency departments (ED ...
Camargo Jr., Carlos A.   +2 more
core  

From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]

open access: yes, 2015
Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
core   +2 more sources

Prognostic markers for idiopathic pulmonary arterial hypertension

open access: yesChinese Medical Journal, 2014
Objective The objective of this study is to review the research on the prognostic markers of idiopathic pulmonary arterial hypertension (IPAH). Date sources We searched literature from PubMed and CNKI databases both in English and Chinese up to 2013.
Xiaomin, Guo, Hongfang, Jin, Junbao, Du
openaire   +2 more sources

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

open access: yesArthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki   +8 more
wiley   +1 more source

Twelve-Year Survival in a Patient With Systemic Sclerosis–Associated Pulmonary Arterial Hypertension on Nifedipine Monotherapy

open access: yesMayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019
Pulmonary arterial hypertension is a progressive vascular disease with a high mortality rate without proper therapy. Identification of the appropriate treatment for each patient is critical in regard to adverse effects, health care costs, ease of ...
Scott A. Helgeson, MD   +5 more
doaj   +1 more source

A Novel Speckle-Tracking Echocardiography Derived Parameter That Predicts Clinical Worsening in Children with Pulmonary Arterial Hypertension

open access: yesApplied Sciences, 2022
Pulmonary arterial hypertension is a severe, progressive disease in children, that causes right ventricular dysfunction over time. Tissue motion annular displacement is a novel speckle-tracking derived echocardiographic parameter used in assessing ...
Iolanda Muntean   +4 more
doaj   +1 more source

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