Results 131 to 140 of about 182,666 (399)
Idiopathic pulmonary fibrosis: An update
Annals of Medicine, 2015 Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults, is thought to arise following an aberrant reparative response to alveolar epithelial cell injury characterized by secretion of excessive amounts of extracellular matrix ...
Spagnolo P1 +6 more
openaire +4 more sources
Animal Models and Experimental Medicine, EarlyView.Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt +7 more
wiley +1 more source
Supersulfide biology and translational medicine for disease control
British Journal of Pharmacology, EarlyView., 2023 Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source
Quantum-inspired Minimum Distance Classification in Biomedical Context [PDF]
arXiv, 2018 We face the problem of pattern classification by proposing a quantum-inspired version of the widely used minimum distance classifier (i.e. the Nearest Mean Classifier (NMC)) already introduced in [31,33,28,27] and by applying this quantum-inspired classifier in a biomedical context.
arxiv
Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets
International Journal of Molecular Sciences, 2019 Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary disease with a median survival of 2–4 years after diagnosis.
Beatriz Ballester, J. Milara, J. Cortijo
semanticscholar +1 more source
Arthritis &Rheumatology, EarlyView.Clinical tools that can aid in the diagnostic differentiation of juvenile dermatomyositis from muscular dystrophy.
Jacqueline A. Madison +9 more
wiley +1 more source
A network model of correlated growth of tissue stiffening in pulmonary fibrosis [PDF]
, 2013 During the progression of pulmonary fibrosis, initially isolated regions of high stiffness form and grow in the lung tissue due to collagen deposition by fibroblast cells. We have previously shown that ongoing collagen deposition may not lead to significant increases in the bulk modulus of the lung until these local remodeled regions have become ...
arxiv +1 more source
Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality? [PDF]
, 2016 Systemic Sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and multiple internal organs and severe functional and structural microvascular alterations.
Jimenez, Sergio A. +1 more
core +2 more sources
Arthritis &Rheumatology, EarlyView.Objective Our objective was to evaluate the efficacy and safety of subcutaneous (SC) abatacept and standard of care (SOC) for the treatment of idiopathic inflammatory myopathy (IIM) over 52 weeks. Methods In this randomized, double‐blind, placebo‐controlled phase III trial, patients with treatment‐refractory IIM received SC abatacept (at 125 mg weekly)
Rohit Aggarwal +5 more
wiley +1 more source
Cells, 2019 Idiopathic pulmonary fibrosis (IPF) has been linked to chronic lung inflammation. Drosha ribonuclease III (DROSHA), a class 2 ribonuclease III enzyme, plays a key role in microRNA (miRNA) biogenesis.
Soo Jung Cho +6 more
doaj +1 more source