Results 151 to 160 of about 207,794 (393)

Ambulatory Oxygen for Pulmonary Fibrosis (OxyPuF): a randomised controlled trial and acceptability study

Health Technology Assessment
Introduction Idiopathic pulmonary fibrosis is a devastating condition of unknown cause that results in progressive, irreversible scarring of the lung, manifesting as breathlessness and dry cough. Idiopathic pulmonary fibrosis is thought to be responsible
Rachel L Adams, Alisha Maher, Nicola Gale, Anjali Crawshaw, David Thickett, Alice M Turner   +5 more
doaj   +1 more source

The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study [PDF]

, 2023
Carl Reynolds, Fabiola Del Greco M, Richard J. Allen, Carlos Flores, Gísli Jenkins, Toby M. Maher, Philip L. Molyneaux, Imre Noth, Justin M. Oldham, Louise V. Wain, Jiyuan An, Jue‐Sheng Ong, Stuart MacGregor, Tom Yates, Paul Cullinan, Cosetta Minelli   +15 more
openalex   +1 more source

Precision medicine advances in idiopathic pulmonary fibrosis

EBioMedicine, 2023
T. Karampitsakos, B. Juan-Guardela, A. Tzouvelekis, J. Herazo-Maya   +3 more
semanticscholar   +1 more source

Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis

Science Translational Medicine, 2019
Interleukin-11 is important for lung fibroblast activation in idiopathic pulmonary fibrosis, and its signaling represents a therapeutic target. Targeting IL-11 in lung fibrosis In idiopathic pulmonary fibrosis (IPF), chronic activation of invasive ...
B. Ng, Jinrui Dong, Giuseppe D’Agostino, S. Viswanathan, A. Widjaja, Wei-Wen Lim, Nicole S. J. Ko, J. Tan, S. Chothani, Benjamin Huang, Chen Xie, C. Pua, A. Chacko, Nuno Guimarães-Camboa, S. Evans, A. Byrne, T. Maher, Jiurong Liang, D. Jiang, P. Noble, S. Schafer, S. Cook   +21 more
semanticscholar   +1 more source

Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice

Exploration, EarlyView.
1. Caffeic acid (CA) is a novel senomorphic. 2. Annexin A5 is the direct protein target of CA in senescent cells. 3. The covalent binding of CA to Annexin A5 protein triggers its degradation, PKCθ deactivation, and the inhibition of the NF‐κB inflammatory pathway. 4. CA effectively alleviates inflammation and lung fibrosis in mouse model.
Yinhua Zhu, Ying Zhang, Qianyu Zhang, Ping Song, Junzhe Zhang, Ang Ma, Chen Wang, Peng Gao, Tong Yang, Lirun Zhou, Qiaoli Shi, Yin Kwan Wong, Yongting Luo, Huan Tang, Jigang Wang   +14 more
wiley   +1 more source

Familial idiopathic pulmonary fibrosis in a young female

Respiratory Medicine Case Reports, 2018
Idiopathic pulmonary fibrosis is a chronic interstitial lung disease of unknown cause. In the past years there have been observations of clustering of pulmonary fibrosis in families, indicating the disease can be inherited.
Sajitha S. Sritharan, Marta E. Gajewska, Anne-Bine S. Skytte, Line Bille Madsen, Elisabeth Bendstrup   +4 more
doaj   +1 more source

Hesperetin Mitigate Idiopathic Pulmonary Fibrosis by Regulating Gut Microbiota and Acetate and Butyrate Levels via the Gut‐Lung Axis

Food Frontiers, EarlyView.
Hesperetin inhibits bleomycin‐induced idiopathic pulmonary fibrosis by regulating gut microbiota and acetate and butyrate levels via the gut‐lung axis. ABSTRACT In the post‐epidemic and aging era, idiopathic pulmonary fibrosis (IPF) has become one of the major diseases endangering human health.
Xia Meng, Zeren Cheng, Xianpu Huang, Mengqi Fu, Ling Shen, Kejing Tang, Shuxun Liu, Mingfei Yao, Qing Gu, Ping Li   +9 more
wiley   +1 more source

Comparison of disease progression subgroups in idiopathic pulmonary fibrosis [PDF]

, 2019
Miia Kärkkäinen, Hannu-Pekka Kettunen, Hanna Nurmi, Tuomas Selander, Minna Purokivi, Riitta Kaarteenaho   +5 more
openalex   +1 more source

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

Advanced Genetics, EarlyView.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]

, 2020
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C, Chapman, Hal A, Engler, Anna E, Guo, Minzhe, Herriges, Michael J, Kathiriya, Jaymin J, Katzen, Jeremy, Kotton, Darrell N, Morrisey, Edward E, Rock, Jason R, Snoeck, Hans-Willem, Vunjak-Novakovic, Gordana, Whitsett, Jeffrey A, Windmueller, Rebecca, Ysasi, Alexandra B, Zacharias, William J   +15 more
core   +1 more source