Results 181 to 190 of about 204,699 (375)
Pirfenidone treatment of idiopathic pulmonary fibrosis
Therapeutics and Clinical Risk Management, 2011 Ye Gan1,2, Erica L Herzog2, Richard H Gomer31Department of Medicine, Central South University, Changsha, Hunan, China; 2Department of Medicine, Yale University School of Medicine, New Haven, CT, USA; 3Department of Biology, Texas A&M University ...
Ye Gan, Erica L Herzog, Richard H Gomer
doaj
Single versus bilateral lung transplantation for idiopathic pulmonary fibrosis [PDF]
, 2000 Bryan F. Meyers +5 more
openalex +1 more source
Telomerase modRNA Offers a Novel RNA‐Based Approach to Treat Human Pulmonary Fibrosis
Aging Cell, EarlyView.Recombinant linear and circular hTERT mRNA restore telomerase activity in primary ATII cells and ex vivo lung tissue from patients with pulmonary fibrosis, leading to telomere elongation, reduced DNA damage, and decreased senescence and fibrosis markers.
Jia Li Ye +14 more
wiley +1 more source
Efectos dun programa de rehabilitación pulmonar en pacientes con fibrosis pulmonar idiopática: unha revisión bibliográfica [PDF]
, 2017 [Resumen] Objetivo. El objetivo principal de la presente revisión bibliográfica es analizar los efectos de un programa de rehabilitación pulmonar en pacientes diagnosticados de fibrosis pulmonar idiopática (FPI). Material y método.
Pérez Díaz, Andrea
core
Aging Cell, EarlyView.Adenine nucleotide translocase 1 (ANT1), a mitochondrial ATP transporter, is decreased in the lung epithelium of aged adults and aged mice correlating to pathogenic airway changes. Loss of ANT1 correlates with increased cellular senescence and changes in COL8A1 in the airway epithelium of the lung.
Roshani Jha +5 more
wiley +1 more source
A Preliminary Study of Long-Term Treatment with Interferon Gamma-1b and Low-Dose Prednisolone in Patients with Idiopathic Pulmonary Fibrosis [PDF]
, 2000 Raymond P. Roos
openalex +1 more source
Aging Cell, EarlyView.The diagram shows that OGC deficiency leads to mitochondrial dysfunction, which activates the PI3K/AKT/Slug pathway and triggers epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial cells. This process promotes myofibroblast accumulation and subretinal fibrosis in laser‐induced CNV, contributing to the progression of AMD.
Mo Wang +9 more
wiley +1 more source
Aging Cell, EarlyView.These findings identify matrix stiffness‐driven cellular senescence as a critical mechanism in silicosis progression, providing a rationale for targeting senescent cells as an antifibrotic therapeutic strategy. ABSTRACT Silicosis is an occupational lung disease characterized by diffuse pulmonary fibrosis resulting from inhalation of silica particles ...
Xinying Zeng +8 more
wiley +1 more source
Occupational and Environmental Risk Factors for Idiopathic Pulmonary Fibrosis: A Multicenter Case-Control Study [PDF]
, 2000 Kathy B. Baumgartner +7 more
openalex +1 more source