Results 191 to 200 of about 207,794 (393)

A Novel Method Using Dual‐Energy Computed Tomography for Detecting Amiodarone‐Induced Lung Injury: A Cohort Pilot Study

Respirology, EarlyView.
There is no gold standard for detecting amiodarone‐induced‐lung injury (AILD). Dual‐Energy‐Computed‐Tomography (DECT) depicts iodine deposition in lungs abnormalities and the liver. We found a substantial correlation between the DECT assessment of AILD and comprehensive clinical evaluation of AILD. DECT can assist in the diagnosis of AILD.
Naama R. Bogot, Ariel Rokach, Irith Hadas‐Halperen, Yehonatan Cohen, Ayal Romem, Moshe Rav‐Acha, Tal Hasin, Gabriel Izbicki, Nissim Arish   +8 more
wiley   +1 more source

Blocking endothelin: breaking new ground

European Respiratory Review, 2007
Endothelin is one of a number of profibrotic cytokines and growth factors, along with transforming growth factor-beta, connective tissue growth factor and tumour necrosis factor-alpha, thought to be involved in the pathogenesis of idiopathic pulmonary ...
R. M. du Bois
doaj  

Inhaled beclomethasone/formoterol in idiopathic pulmonary fibrosis: A randomised controlled exploratory study [PDF]

, 2017
Brindle, Kayleigh, Crooks, Michael G., Fraser, Simon D., Hart, Simon P., Morice, Alyn H., Wright, Caroline E.   +5 more
core   +2 more sources

Immunological landscape of radiation‐induced cardiac injury

VIEW, EarlyView.
Abstract Radiation‐induced heart disease (RIHD) is a serious complication of radiotherapy and a major contributor to non‐cancer mortality. This study employs single‐cell RNA sequencing technology to investigate the dynamic immune landscape following radiation‐induced cardiac injury, uncovering potential mechanisms of RIHD and providing strategies for ...
Huan Liu, Dan Ou, Han Zhao, Ran Wu, Keman Liao, Jianyi Zhao, Zhou Li, Zhe Xu, Yuerui Wang, Lu Cao, Yingying Lin, Jia‐Yi Chen   +11 more
wiley   +1 more source

Cardiac magnetic resonance quantification of epicardial adipose tissue identifies subclinical cardiac dysfunction in asymptomatic obesity: A multicenter cross‐sectional study

VIEW, EarlyView.
Epicardial adipose tissue (EAT) is implicated in obesity‐related heart failure, yet its association with subclinical cardiac dysfunction in asymptomatic obese individuals remains unclear. This prospective multicenter study used cardiac magnetic resonance to quantify EAT volume and assess cardiac morphology and systolic/diastolic function in 87 ...
Xu Wang, Hang Zhao, Jiang Yue, Yezi Chai, Jing Ma, Meng Jiang, Jun Pu   +6 more
wiley   +1 more source

Faculty Opinions recommendation of Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation.

, 2016
Toby M. Maher
openalex   +2 more sources

Targeting PI3K/AKT signaling for treatment of idiopathic pulmonary fibrosis

Acta Pharmaceutica Sinica B, 2021
Jincheng Wang, Kaili Hu, Xuanyan Cai, Bo Yang, Qiaojun He, Jiajia Wang, Qinjie Weng   +6 more
semanticscholar   +1 more source

DLD‐HLNP/P@IR780 for efficient lung‐parenchyma accumulation to treat idiopathic pulmonary fibrosis

VIEW, EarlyView.
DLD‐HLNP/P@IR780 was synthesized to target to lung and treat IPF by releasing pirfenidone. It could effectively traverse pulmonary ECB and accumulate in lung parenchyma by IR780 binding to CD300LF and MRC1 which are abundantly and specifically expressed on pulmonary endothelial cell and pulmonary macrophages.
Mengzhu Wang, Na Zhuang, Juan Feng, Cheng Qian   +3 more
wiley   +1 more source

In-Hospital Mortality in Patients with Idiopathic Pulmonary Fibrosis Prior to and Following Approval of Antifibrotic Drugs [PDF]

, 2020
Jennifer Judy, Michael T. Durheim, Shaun Bender, Megan L. Neely, Dorothy Baumer, Sandra Robinson, Craig Conoscenti, Thomas B. Leonard, Howard M. Lazarus, Scott M. Palmer   +9 more
openalex   +1 more source

A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

New England Journal of Medicine, 2014
T. King, W. Bradford, S. Castro-Bernardini, E. Fagan, I. Glaspole, M. Glassberg, E. Gorina, P. Hopkins, D. Kardatzke, L. Lancaster, D. Lederer, S. Nathan, C. Pereira, S. Sahn, R. Sussman, J. Swigris, P. Noble   +16 more
semanticscholar   +1 more source