Blocking endothelin: breaking new ground
Endothelin is one of a number of profibrotic cytokines and growth factors, along with transforming growth factor-beta, connective tissue growth factor and tumour necrosis factor-alpha, thought to be involved in the pathogenesis of idiopathic pulmonary ...
R. M. du Bois
doaj
Regulation of the effects of TGF-beta 1 by activation of latent TGF-beta 1 and differential expression of TGF-beta receptors (Tbeta R-I and Tbeta R-II) in idiopathic pulmonary fibrosis [PDF]
Nasreen Khalil
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SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy+17 more
wiley +1 more source
Single lung transplantation from a brain-dead donor for a patient with idiopathic pulmonary fibrosis [PDF]
Shinichiro Miyoshi+5 more
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Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post+4 more
wiley +1 more source
Lung Cancer in Patients with Idiopathic Pulmonary Fibrosis.
Atsushi Nagai+3 more
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Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder [PDF]
Moisés Selman, Annie Pardo
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Targeting PI3K/AKT signaling for treatment of idiopathic pulmonary fibrosis
Jincheng Wang+6 more
semanticscholar +1 more source
Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP) [PDF]
João Valente Barbas‐Filho
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International consensus statement on idiopathic pulmonary fibrosis [PDF]
Ulrich Costabel, Talmadge E. King
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