Inhibition of phosphodiesterases 1 and 4 prevents myofibroblast transformation in Peyronie's disease
Objectives To investigate which phosphodiesterase (PDE) isoforms are expressed in fibroblasts isolated from the tunica albuginea (TA) of patients with Peyronie's disease (PD), and to measure the potency of PDE inhibitors in preventing transformation of these fibroblasts to profibrotic myofibroblasts.
Sophie L. Harding+4 more
wiley +1 more source
Epstein–Barr virus and wild p53 in idiopathic pulmonary fibrosis
She Lok+4 more
openalex +1 more source
Does interferon- improve pulmonary function in idiopathic pulmonary fibrosis? [PDF]
Antje Prasse+4 more
openalex +1 more source
Beneficial Impact of Nutritional Therapy on Idiopathic Pulmonary Fibrosis. [PDF]
Yamakawa H+3 more
europepmc +1 more source
Natural products targeting tumour angiogenesis
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu+2 more
wiley +1 more source
The Therapeutic Effect of Angiotensin II Receptor Antagonist in Idiopathic Pulmonary Fibrosis [PDF]
Duck Soo Woo+7 more
openalex +1 more source
The enigma of idiopathic pulmonary fibrosis in upper middle-aged individuals. [PDF]
Devalla L, Ghewade B, Wagh P, Alone V.
europepmc +1 more source
MLL1/WDR5 inhibition is a promising strategy for treating peritoneal fibrosis by reducing H3K4me3 and p16INK4a expression. Inhibitors MM‐102 and OICR‐9429 suppress fibrosis, inflammation, and senescence in TGF‐β1‐stimulated HPMCs and MGO‐injected mice, improving peritoneal function.
Daisuke Hara+13 more
wiley +1 more source
Idiopathic Pulmonary Fibrosis: Impact of Angiotensin Converting Enzyme Inhibitors and HMG-CoA Reductase Inhibitor s on Survival [PDF]
Hassan F. Nadrous+4 more
openalex +1 more source
The pathogenesis of idiopathic pulmonary fibrosis: from "folies à deux" to "Culprit cell Trio". [PDF]
Chilosi M+5 more
europepmc +1 more source