Results 1 to 10 of about 44,908 (144)

Hyperuricemia Aggravates IgA Nephropathy [PDF]

مجله دانشکده پزشکی اصفهان, 2013
It is well documented that hyperuricemia is an independent risk factor for IgA nephropathy, and appropriate treatment by allopurinol is a reasonable modality in the patients.
Mahmoud Rafieian-Kopaei, Shamin Ghobadi, Hamid Nasri   +2 more
doaj   +2 more sources

Early Experience With Iptacopan for Recurrent IgA Nephropathy After Kidney Transplantation [PDF]

Kidney Medicine
Immunoglobulin A (IgA) nephropathy is a common cause of kidney failure and can recur after kidney transplantation, increasing the risk of allograft loss.
Ayman Al Jurdi, Abraham Cohen Bucay, Pitchaphon Nissaisorakarn, Hannah Gilligan, Claire T. Avillach, Veronica E. Klepeis, Rex N. Smith, Ragnar Palsson, Kassem Safa, Leonardo V. Riella   +9 more
doaj   +2 more sources

Relapses or de-novo IgA nephropathy following COVID-19 vaccination; a narrative review [PDF]

Journal of Nephropathology, 2023
Immunoglobulin A (IgA) nephropathy is the most common type of glomerulonephritis worldwide characterized by excessive serum levels of glycosylated which triggers the generation of glycan-specific IgG and IgA autoantibodies.
Masoud Hafizi, Maryam Khosravian, Payam Peymani, Shahrzad Alimohammadi, Shokouh Shayanpour, Hamid Reza Jahantigh   +5 more
doaj   +1 more source

KM55 in the evaluation of IgA containing glomerular diseases

Glomerular Diseases, 2021
Introduction: Mucosal derived galactose deficient IgA is central to the pathogenesis of primary IgA nephropathy. Recent reports suggest similar pathogenesis in Henoch Schonlein purpura and secondary IgA nephropathy.
Rahul Raj, Alok Sharma, Adarsh Barwad, Soumita Bagchi, Sanjay Kumar Agarwal, Arvind Bagga, Amit Kumar Dinda, Geetika Singh   +7 more
doaj   +1 more source

Diagnostic Potential of Plasma IgA1 O-Glycans in Discriminating IgA Nephropathy From Other Glomerular Diseases and Healthy Participants

Frontiers in Molecular Biosciences, 2022
Background: Aberrant O-glycosylation of IgA1 plays an important role in IgA nephropathy pathogenesis. Previous proteomic studies analyzed O-glycans of the circulating IgA1 hinge region and found that the N-acetylgalactosamine (GalNAc) and galactose ...
Shuyu Zhang, Haidan Sun, Zejian Zhang, Menglin Li, Zhengguang Guo, Wenling Ye, Guangyan Cai, Wei Sun, Mingxi Li   +8 more
doaj   +1 more source

Histological Features of IgA Nephropathy in Pediatrics and the Magnitude of the Disease in Saudi Children

International Journal of Pediatrics, 2023
Objectives. This review addresses the microscopic features of immunoglobulin A nephropathy (IgA nephropathy), its prognostic variables in children, and measures to which extent these features and variables differ from adults.
Reem A. Al Zahrani
doaj   +1 more source

COVID-19 Hyperinflammation: What about Neutrophils?

mSphere, 2020
COVID-19 is often related to hyperinflammation that drives lung or multiorgan injury. The immunopathological mechanisms that cause excessive inflammation are under investigation and constantly updated.
Athanasios Didangelos
doaj   +1 more source

Urinary exosomal miRNA signature of IgA nephropathy: a case–control study

Scientific Reports, 2023
IgA nephropathy is the most common primary glomerulonephritis worldwide and can progress to end-stage kidney disease (ESKD). The current “gold standard” for diagnosis is kidney biopsy, which is invasive and associated with morbidity.
Mythri Shankar, Aditya Shetty, Madhura N.S., Sreedhara C.G., Kishan A., Karthik Tennankore   +5 more
doaj   +1 more source

Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathy. [PDF]

PLoS ONE, 2018
IgA nephropathy is an autoimmune disease characterized by IgA1-containing glomerular immune deposits. We previously proposed a multi-hit pathogenesis model in which patients with IgA nephropathy have elevated levels of circulatory IgA1 with some O ...
William J Placzek, Hiroyuki Yanagawa, Yuko Makita, Matthew B Renfrow, Bruce A Julian, Dana V Rizk, Yusuke Suzuki, Jan Novak, Hitoshi Suzuki   +8 more
doaj   +1 more source

Current knowledge of targeted-release budesonide in immunoglobulin A nephropathy: A comprehensive review

Frontiers in Immunology, 2023
Immunoglobulin A (IgA) nephropathy is a common autoimmune kidney disease. Accumulating studies showed that IgA nephropathy may be partially correlated with mucosal immune system dysfunction.
Jian Liao, Yijing Zhou, Xiuqin Xu, Ke Huang, Pengtao Chen, Yuhao Wu, Biao Jin, Qianlong Hu, Guanlin Chen, Shankun Zhao   +9 more
doaj   +1 more source