Results 21 to 30 of about 31,703 (224)
KM55 in the evaluation of IgA containing glomerular diseases
Glomerular Diseases, 2021 Introduction: Mucosal derived galactose deficient IgA is central to the pathogenesis of primary IgA nephropathy. Recent reports suggest similar pathogenesis in Henoch Schonlein purpura and secondary IgA nephropathy.
Rahul Raj +7 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Background: Aberrant O-glycosylation of IgA1 plays an important role in IgA nephropathy pathogenesis. Previous proteomic studies analyzed O-glycans of the circulating IgA1 hinge region and found that the N-acetylgalactosamine (GalNAc) and galactose ...
Shuyu Zhang +8 more
doaj +1 more source
International Journal of Pediatrics, 2023 Objectives. This review addresses the microscopic features of immunoglobulin A nephropathy (IgA nephropathy), its prognostic variables in children, and measures to which extent these features and variables differ from adults.
Reem A. Al Zahrani
doaj +1 more source
COVID-19 Hyperinflammation: What about Neutrophils?
mSphere, 2020 COVID-19 is often related to hyperinflammation that drives lung or multiorgan injury. The immunopathological mechanisms that cause excessive inflammation are under investigation and constantly updated.
Athanasios Didangelos
doaj +1 more source
Urinary exosomal miRNA signature of IgA nephropathy: a case–control study
Scientific Reports, 2023 IgA nephropathy is the most common primary glomerulonephritis worldwide and can progress to end-stage kidney disease (ESKD). The current “gold standard” for diagnosis is kidney biopsy, which is invasive and associated with morbidity.
Mythri Shankar +5 more
doaj +1 more source
Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathy. [PDF]
PLoS ONE, 2018 IgA nephropathy is an autoimmune disease characterized by IgA1-containing glomerular immune deposits. We previously proposed a multi-hit pathogenesis model in which patients with IgA nephropathy have elevated levels of circulatory IgA1 with some O ...
William J Placzek +8 more
doaj +1 more source
Frontiers in Immunology, 2023 Immunoglobulin A (IgA) nephropathy is a common autoimmune kidney disease. Accumulating studies showed that IgA nephropathy may be partially correlated with mucosal immune system dysfunction.
Jian Liao +9 more
doaj +1 more source
Lack of serologic evidence to link IgA nephropathy with celiac disease or immune reactivity to gluten. [PDF]
PLoS ONE, 2014 IgA nephropathy is the most common form of primary glomerulonephritis worldwide. Mucosal infections and food antigens, including wheat gluten, have been proposed as potential contributing environmental factors.
Sina Moeller +7 more
doaj +1 more source
Journal of the American Society of Nephrology, 2005 14863
Barratt, J, Feehally, J
openaire +3 more sources
Serological Measurement of Poly-IgA Immune Complex Levels in IgA Nephropathy and IgA Vasculitis
Bio-Protocol, 2022 Both IgA nephropathy and IgA vasculitis, formerly known as Henoch-Schӧnlein purpura, are immune deposition diseases. IgA nephropathy is caused by the deposition of aberrantly formed poly-IgA complexes from blood circulation to the kidney glomerulus; IgA ...
Xue Zhang +6 more
doaj +1 more source