Results 31 to 40 of about 161,533 (212)
The Treatment of IgA Nephropathy [PDF]
Kidney Diseases, 2015 <b><i>Background:</i></b> IgA nephropathy (IgAN) is a very common glomerulonephritis worldwide. Nevertheless, treatment options for primary IgAN are still largely based on opinion or weak evidence. There is a lack of large randomized controlled trials (RCT) that provide a definitive immunosuppressive protocol for IgAN.
Leung, JCK, Lai, KN, Tang, SCW
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The Role of IgA in the Pathogenesis of IgA Nephropathy [PDF]
International Journal of Molecular Sciences, 2019 Immunoglobulin A (IgA) is the most abundant antibody isotype produced in humans, predominantly present in the mucosal areas where its main functions are the neutralization of toxins, prevention of microbial invasion across the mucosal epithelial barrier, and simultaneous maintenance of a physiologically indispensable symbiotic relationship with ...
Martina Perše, Željka Večerić-Haler
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Frontiers in Genetics, 2022 Objective: RNA-binding proteins (RBPs) are essential for most post-transcriptional regulatory events, which exert critical roles in nearly all aspects of cell biology.
Xueqin Zhang +7 more
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IgA nephropathy in a patient with ankylosing spondylitis well controlled with etanercept [PDF]
Kosin Medical Journal, 2018 Ankylosing spondylitis (AS) can involve the eye, gastrointestinal system, cardiopulmonary system, skin, kidneys, and spinal and peripheral joints. It is rarely accompanied by immunoglobulin A (IgA) nephropathy. Although IgA is involved in both AS and IgA
Do-Hyeong Lee +3 more
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STEMedicine, 2023 Purpose: Antiplatelet aggregation drugs, such as aspirin, can alleviate pathological renal damage in immunoglobulin A (IgA) nephropathy, although the precise mechanism is unclear.
Nomvula Johannes, Priyanka Maunga
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IgA Glycosylation in IgA Nephropathy [PDF]
, 1998 IgA nephropathy (IgAN) is the commonest form of glomerulonephritis in developed countries where renal biopsy is widely practiced1. IgAN is defined by the deposition of IgA in the glomerular mesangium. Most typically, patients present with episodes of visible haematuria, which often concide with respiratory or gastrointestinal infection.
A, Allen, J, Feehally
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PLoS ONE, 2019 IgA nephropathy, a common chronic kidney disease, has various possible outcomes. Therefore, the identification of novel prognostic biomarkers is needed.
Makoto Kurano, Yutaka Yatomi
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Clinical Immunology, 2016 IgA nephropathy (IgAN) is the leading cause of primary glomerulonephritis in the world. The disease is characterized by the presence of IgA-containing immune complexes in the circulation and in mesangial deposits with ensuing glomerular injury. Although in humans there are two IgA subclasses, only IgA1 molecules are involved.
Jiri, Mestecky +3 more
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Advances in genetics of Immunoglobulin A Nephropathy.
, 2016 In the chapter genetic characteristics of IgA Nephropathy are ...
Ali Gharavi +5 more
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Novel Treatment Paradigms: Primary IgA Nephropathy
Kidney International ReportsIgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Approximately 30% to 45% of patients progress to kidney failure (KF) within 20 to 25 years of diagnosis, and there has long been a lack of effective treatments.
Haresh Selvaskandan +2 more
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