Results 31 to 40 of about 149,546 (225)
Plasma phospholipid metabolic profiling and biomarkers of mouse IgA nephropathy
, 2006 IgA nephropathy is the most common form of glomerulonephritis (GN) and it Could progress to end-stage renal failure within 10 years. Participating in biological processes in various pathways, phospholipids as a class of important Constituents in the ...
许国旺 +5 more
core +1 more source
Novel Treatment Paradigms: Primary IgA Nephropathy
Kidney International ReportsIgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Approximately 30% to 45% of patients progress to kidney failure (KF) within 20 to 25 years of diagnosis, and there has long been a lack of effective treatments.
Haresh Selvaskandan +2 more
doaj +1 more source
Steroid therapy is effective for IgA nephropathy after liver transplantation in a pediatric patient
Clinical Case Reports, 2021 Hepatic IgA nephropathy is a complication of chronic liver disease. IgA nephropathy after liver transplantation is rare, especially in children, and carries a significant risk factor for chronic renal failure and mortality.
Hiroshi Tamura +2 more
doaj +1 more source
Clinical Immunology, 2016 IgA nephropathy (IgAN) is the leading cause of primary glomerulonephritis in the world. The disease is characterized by the presence of IgA-containing immune complexes in the circulation and in mesangial deposits with ensuing glomerular injury. Although in humans there are two IgA subclasses, only IgA1 molecules are involved.
Jiri, Mestecky +3 more
openaire +2 more sources
Do IgA nephropathy presentations display any seasonality? [PDF]
, 2021 IgA nephropathy (IgAN) is the most common glomerulonephritis and one of the most common causes of chronic kidney disease worldwide. Although IgAN has been classically linked with respiratory tract infections (RTIs), little studies have examined the ...
Ming-Wei Lin, Adrian Y. S. Lee
core +2 more sources
Immunoglobulin A-nephropathy: modern view of the problem and treatment options
Лечащий Врач, 2021 The presented review discusses the mechanisms of development, the issues of diagnosis and the possibility of therapy for IgAnephropathy. IgA-nephropathy is an immunocomplex lesion of the glomeruli, characterized by the predominant deposition of ...
I. T. Murkamilov +3 more
doaj +1 more source
The Emerging Role of Complement Proteins as a Target for Therapy of IgA Nephropathy
Frontiers in Immunology, 2019 IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a common cause of end-stage renal disease. Evaluation of a kidney biopsy is necessary for diagnosis, with routine immunofluorescence microscopy revealing dominant ...
Dana V. Rizk +7 more
doaj +1 more source
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
Kidney & Blood Pressure Research, 2014 Background/Aims: Our aim was to explore the molecular mechanism underlying development of IgA nephropathy and discover candidate agents for IgA nephropathy.
Jinling Wang, Juan Cao
doaj +1 more source
Possible Link between IgA Nephropathy and B-cell Acute Lymphoblastic Leukemia
Turkish Journal of Nephrology, 2020 IgA nephropathy (IgA-N) is the most common glomerulonephritis type globally. IgA-N is usually accepted as a kidney disease; however, IgA-N has been reported with infections, autoimmune diseases, and malignancies in the literature.
Eray Eroğlu +7 more
doaj +1 more source