Results 51 to 60 of about 25,586 (182)
Kidney International, 1995 IgAN is the most common type of glomerulonephritis worldwide, and is found more in men and distinctly less in blacks. It presents with macroscopic hematuria in about 40 to 45% of patients, with microscopic hematuria and proteinuria in about 35 to 40%, and with nephrotic syndrome or acute renal failure in the remainder.
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Journal of Nobel Medical CollegeBackground: IgA nephropathy is the most prevalent primary glomerulonephritis worldwide, characterized by the mesangial deposition of IgA immune complexes.Its clinical course is highly variable, ranging from indolent to rapidly progressive forms, and it ...
Nirajan Mainali, Keshika Kshatree
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Experimental Physiology, EarlyView.Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu +7 more
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Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.Diagnostic value of BTG2 and its immunoregulatory mechanism in IgAN. This study reveals that BTG2 improves immune microenvironment dysregulation, attenuates inflammation, and reduces fibrosis by promoting the expansion of T follicular helper cells, inducing macrophage polarization toward an M2 anti‐inflammatory phenotype, and inhibiting the TGF‐β1 ...
Min Kou +4 more
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Research advances on the pathogenesis of IgA nephropathy
Linchuang shenzangbing zazhi, 2022 IgA nephropathy is the most common primary glomerular disease in the world. Up to 20%-40% of patients develop end-stage renal disease within 20 years after a definite diagnosis of renal biopsy.
Lu Fang-cao, Yuan Hong-ling
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Food Science &Nutrition, Volume 14, Issue 8, August 2026.CP suppresses NLRP3 inflammasome activation through modulation of the gut microbiota, thereby exerting protective effects against ulcerative colitis. ABSTRACT Enteral nutrition is an important intervention for ulcerative colitis, and collagen can improve immune responses and repair the intestinal barrier.
Longyi Piao +7 more
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BMC NephrologyIgA nephropathy, presently recognized as the foremost primary glomerular disorder, emerges as a principal contributor to renal failure globally, with its pathogenesis yet to be fully elucidated. Extensive research has highlighted the critical role of gut
Yitao Fan, Yan Wang, Han Xiao, Hui Sun
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A case presentation of an IgA nephropathy patient with Vogt-Koyanagi-Harada syndrome
BMC Nephrology, 2020 Background Vogt-Koyanagi-Harada syndrome is a rare disease characterized by skin and eyelash bleaching, chronic granulomatous iridocyclitis and exudative retinal detachment, and aseptic meningitis and encephalopathy.
Quan Zhang +3 more
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The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta +2 more
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Urinary uromodulin excretion predicts progression of chronic kidney disease resulting from IgA nephropathy. [PDF]
PLoS ONE, 2013 BACKGROUND: Uromodulin, or Tamm-Horsfall protein, is the most abundant urinary protein in healthy individuals. Recent studies have suggested that uromodulin may play a role in chronic kidney diseases.
Jingjing Zhou +7 more
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