Results 51 to 60 of about 149,546 (225)

Association of urinary NGAL and early diagnosis and prognosis of IgA nephropathy

Zhongguo linchuang yanjiu, 2023
Objective To investigate the value of urinary neutrophil gelatinase-associated lipocalin (NGAL) in the early diagnosis of IgA nephropathy and its relationship with the cumulative survival rate of kidney in patients with IgA nephropathy.
SHI Jia-jia*, ZHU Guo-zhen
doaj   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source

Exploring the causal effect of complement and IgA nephropathy—a Mendelian randomization study

Renal Failure
IgA nephropathy, one of the most common primary glomerulonephritis worldwide, is still under investigation for its precise etiology. The widely accepted theory is the ‘four-hit model’ and subsequent complement and inflammatory responses.
Han Xu, Mengxiao Zou, Yichun Cheng, Shuwang Ge   +3 more
doaj   +1 more source

Efficacy and safety of artesunate for patients with IgA nephropathy: a study protocol for a multicenter, double-blind, randomized, placebo-controlled trial

Trials, 2022
Background IgA nephropathy is the most common glomerular disease and is a common cause of progression to end-stage renal disease in patients with kidney diseases.
Qi Chen, Zi Wang, Jicheng Lv, Lijun Liu, Hang Li, Weiwei Sun, Yanhong Huo, Yingbo Guo, Cun Shen, Shichao Li, Zhenjie Chen, Jingwei Zhou   +11 more
doaj   +1 more source

Efficacy and Safety of SGLT2 Inhibitors in Patients With Genetic Lipodystrophy: A Real‐Life Experience From a National Reference Network

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Lipodystrophy syndromes are rare diseases with metabolic and cardiovascular consequences. This study explores the metabolic and renal effects of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with genetic lipodystrophy. Patients and Methods Patients with familial partial lipodystrophy (n = 57) or congenital generalised ...
Léna Robert, Ines Belalem, Corinne Vigouroux, Hippolyte Dupuis, Marie Christine Vantyghem, Mathilde Simonson, Estelle Nobecourt, Héléna Mosbah, Sophie Beliard, Stéphanie Jellimann, Sonja Janmaat, Camille Vatier, Sophie Lamothe   +12 more
wiley   +1 more source

Coexisting genetic kidney disease explains many cases of ‘familial’ IgA nephropathy where the proband has biopsy-confirmed mesangial IgA deposits

Frontiers in Medicine
BackgroundOne in seven people with IgA nephropathy has another apparently-affected family member. This study examined how often biopsy-proven familial and sporadic IgA nephropathy were associated with genetic kidney disease.MethodsEleven unrelated people
YuXin Li, Jing Zhang, Zhuo Jun Yin, Ziming Zhou, Bocheng Huang, Khalid Mahmood, Deb Colville, David Barit, Russell Auwardt, Robert Fassett, Kathy Paizis, Francesco Ierino, Timothy Pianta, David Langsford, Mary Huang, Judy Savige   +15 more
doaj   +1 more source

Half a century of IgA nephropathy: achievements, frustrations and challenges

Український Журнал Нефрології та Діалізу, 2018
IgA nephropathy is the most common glomerulonephritis worldwide. This disease has a tremendous economic impact because renal replacement therapy is expensive and hard-to-reach.
I.I. Lapchynska
doaj   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Crescentic IgA Nephropathy

Medicine, 1984
We report five cases of crescentic IgA nephropathy. All are males, 16-60 years of age. One case each came to medical attention with uremia, nephrotic syndrome, and gross hematuria; two cases presented with microhematuria and proteinuria on routine urinalysis. All had hypertension, azotemia (serum creatinine 1.6-9.4 mg/dl), proteinuria (greater than 6 g/
J G, Abuelo, A R, Esparza, R A, Matarese, R G, Endreny, J S, Carvalho, S R, Allegra   +5 more
openaire   +2 more sources

Evaluating a New International Risk-Prediction Tool in IgA Nephropathy

, 2019
ImportanceAlthough IgA nephropathy (IgAN) is the most common glomerulonephritis in the world, there is no validated tool to predict disease progression. This limits patient-specific risk stratification and treatment decisions, clinical trial recruitment,
Katafuchi, Ritsuko, Matsuzaki, Keiichi, Reich, Heather N, Magistroni, Riccardo, Zhang, Hong, Espino-Hernandez, Gabriela, Feehally, John, Liu, Zhi-Hong, Coppo, Rosanna, Kim, S Joseph, Cattran, Daniel C., Barbour, Sean J, Er, Lee, Suzuki, Yusuke, For The International IgA Nephropathy   +14 more
core   +1 more source