Results 61 to 70 of about 31,703 (224)

Evaluating a New International Risk-Prediction Tool in IgA Nephropathy

, 2019
ImportanceAlthough IgA nephropathy (IgAN) is the most common glomerulonephritis in the world, there is no validated tool to predict disease progression. This limits patient-specific risk stratification and treatment decisions, clinical trial recruitment,
Katafuchi, Ritsuko, Matsuzaki, Keiichi, Reich, Heather N, Magistroni, Riccardo, Zhang, Hong, Espino-Hernandez, Gabriela, Feehally, John, Liu, Zhi-Hong, Coppo, Rosanna, Kim, S Joseph, Cattran, Daniel C., Barbour, Sean J, Er, Lee, Suzuki, Yusuke, For The International IgA Nephropathy   +14 more
core   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Exploring the causal effect of complement and IgA nephropathy—a Mendelian randomization study

Renal Failure
IgA nephropathy, one of the most common primary glomerulonephritis worldwide, is still under investigation for its precise etiology. The widely accepted theory is the ‘four-hit model’ and subsequent complement and inflammatory responses.
Han Xu, Mengxiao Zou, Yichun Cheng, Shuwang Ge   +3 more
doaj   +1 more source

Association of urinary NGAL and early diagnosis and prognosis of IgA nephropathy

Zhongguo linchuang yanjiu, 2023
Objective To investigate the value of urinary neutrophil gelatinase-associated lipocalin (NGAL) in the early diagnosis of IgA nephropathy and its relationship with the cumulative survival rate of kidney in patients with IgA nephropathy.
SHI Jia-jia*, ZHU Guo-zhen
doaj   +1 more source

Bifidobacterium bifidum G9‐1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open‐Label, Randomized Controlled Trial (Binary STAR Study)

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5952-5967, July 2026.
ABSTRACT Aims To evaluate the effects of probiotics Bifidobacterium bifidum G9‐1 (BBG9‐1) on gastrointestinal symptoms in patients with Type 2 diabetes mellitus (T2DM) with diarrhoea or constipation. Materials and Methods In a 12‐week open‐label randomised controlled trial, 100 participants were randomized 1:1 to a control or BBG9‐1 group, with 12 mg ...
Genki Kobayashi, Yoshitaka Hashimoto, Tomoyuki Matsuyama, Noriyuki Kitagawa, Saori Majima, Takafumi Senmaru, Emi Ushigome, Hiroshi Okada, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +10 more
wiley   +1 more source

Efficacy and safety of artesunate for patients with IgA nephropathy: a study protocol for a multicenter, double-blind, randomized, placebo-controlled trial

Trials, 2022
Background IgA nephropathy is the most common glomerular disease and is a common cause of progression to end-stage renal disease in patients with kidney diseases.
Qi Chen, Zi Wang, Jicheng Lv, Lijun Liu, Hang Li, Weiwei Sun, Yanhong Huo, Yingbo Guo, Cun Shen, Shichao Li, Zhenjie Chen, Jingwei Zhou   +11 more
doaj   +1 more source

Advances in genetics of Immunoglobulin A Nephropathy.

, 2016
In the chapter genetic characteristics of IgA Nephropathy are ...
Ali Gharavi, Zhang, Hong, MAGISTRONI, Riccardo, Hong Zhang, Riccardo Magistroni, Gharavi, Ali   +5 more
core   +1 more source

Coexisting genetic kidney disease explains many cases of ‘familial’ IgA nephropathy where the proband has biopsy-confirmed mesangial IgA deposits

Frontiers in Medicine
BackgroundOne in seven people with IgA nephropathy has another apparently-affected family member. This study examined how often biopsy-proven familial and sporadic IgA nephropathy were associated with genetic kidney disease.MethodsEleven unrelated people
YuXin Li, Jing Zhang, Zhuo Jun Yin, Ziming Zhou, Bocheng Huang, Khalid Mahmood, Deb Colville, David Barit, Russell Auwardt, Robert Fassett, Kathy Paizis, Francesco Ierino, Timothy Pianta, David Langsford, Mary Huang, Judy Savige   +15 more
doaj   +1 more source

IgA nephropathy

Kidney International, 1995
IgAN is the most common type of glomerulonephritis worldwide, and is found more in men and distinctly less in blacks. It presents with macroscopic hematuria in about 40 to 45% of patients, with microscopic hematuria and proteinuria in about 35 to 40%, and with nephrotic syndrome or acute renal failure in the remainder.
openaire   +2 more sources

Correlation of Serum Immunoglobulin A and Immunoglobulin A / Complement 3 Ratio with IgA Nephropathy: One Year Prospective Study

Journal of Nobel Medical College
Background: IgA nephropathy is the most prevalent primary glomerulonephritis worldwide, characterized by the mesangial deposition of IgA immune complexes.Its clinical course is highly variable, ranging from indolent to rapidly progressive forms, and it ...
Nirajan Mainali, Keshika Kshatree
doaj   +1 more source