Results 71 to 80 of about 25,586 (182)

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang, Mengxuan Chen, Yan Ge, William Gunning, Rujun Gong   +4 more
wiley   +1 more source

IgA nephropathy with leucocytoclastic vasculitis

Journal of International Medical Research, 2018
Leucocytoclastic vasculitis is a rare type of allergic disease caused by immune complexes. IgA nephropathy is a glomerulopathy characterized by recurrent episodes of gross haematuria or microscopic haematuria and IgA deposition in the glomerular ...
Lin-Yan Wei, Chao Liu, Ya-Li Zhang, Guo-Liang Li   +3 more
doaj   +1 more source

Sparsentan in IgA nephropathy: a plain language summary of publication for the PROTECT study

Therapeutic Advances in Rare Disease
Summary What is this summary about? Sparsentan (FILSPARI ® ) is a once-daily pill for people with Immunoglobulin A (IgA) nephropathy who are at high risk for worsening kidney disease.
Brad H. Rovin, Radko Komers, Chris Scroggins, Jonathan Barratt   +3 more
doaj   +1 more source

Diagnosis and treatment of patients with IgA nephropathy in Japan

Kidney Research and Clinical Practice, 2016
Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. Although CKD is not one specific disease, it is a comprehensive syndrome that includes IgA nephropathy.
Yasuhiko Tomino
doaj   +1 more source

A case of rapidly progressive IgA nephropathy in a patient with exacerbation of Crohn’s disease

BMC Nephrology, 2012
Background IgA nephropathy has been reported as a renal involvement in Crohn’s disease. Crescentic IgA nephropathy, which accounts for fewer than 5% of cases of IgA nephropathy, has a poorer prognosis than other forms of crescentic glomerulonephritis. We
Choi Ji-Young, Yu Chung, Jung Hee-Yeon, Jung Min, Kim Yong-Jin, Cho Jang-Hee, Kim Chan-Duck, Kim Yong-Lim, Park Sun-Hee   +8 more
doaj   +1 more source

Exploration of Artemisinin Against IgA Nephropathy via AKT/Nrf2 Pathway by Bioinformatics and Experimental Validation

Drug Design, Development and Therapy, 2023
Wei-guang Yang,* Ao Sun,* Rong Zhu, Nan Liu, Wei-jie He, Lin-lin Liu Department of Nephrology, The First Affiliated Hospital of China Medical University, Shen Yang, Liao Ning, People’s Republic of China*These authors contributed equally to ...
Yang WG, Sun A, Zhu R, Liu N, He WJ, Liu LL   +5 more
doaj  

IgA Nephropathy in North West Frontier Province of Pakistan

Gomal Journal of Medical Sciences, 2004
Background: IgA nephropathy is the most common form of glomerulonephritis in the world. The extent to which IgA nephropathy is diagnosed depends upon the local attitude towards urine testing and renal biopsy.
Mohammad Noor, Sultan Mahmood, Jamal Khan, Wazir Mohammad, Dilawar Shah   +4 more
doaj  

A case of renal hypouricemia due to T217M mutation in SLC22A12 incidentally associated with IgA nephropathy

Clinical Case Reports
Key Clinical Message A T217M heterozygous mutation in the SLC22A12 gene caused renal hypouricemia; this patient with IgA nephropathy had no findings other than IgA nephropathy on renal biopsy.
Yoshimasa Sakurabu, Haruhito A. Uchida, Toshihisa Tahara, Tomohiko Asakawa, Haruka Yamasaki, Katsuyoshi Katayama, Shugo Okamoto, Yasuhiro Onishi, Natsumi Matsuoka‐Uchiyama, Keiko Tanaka, Hidemi Takeuchi, Kenji Tsuji, Ryoko Umebayashi, Yuki Ohashi, Kimiyoshi Ichida, Jun Wada   +15 more
doaj   +1 more source

Prevalence of IgA Nephropathy: A 10 Years’ Experience from Jinnah Postgraduate Medical Centre, Karachi, Pakistan

Pakistan Journal of Medicine and Dentistry
Background: Immunoglobulin A (IgA) is considered the most frequently dealt primary glomerulonephritis, worldwide. The Berger’s disease or IgA nephropathy is a mesangial proliferative glomerulonephritis characterized by deposition of immunoglobulin A ...
Muhammad Ali, Shafique Ahmed, Ayesha Ejaz, Ghazala Usman, Abdul MananJunejo, Hina Iram, Moiz Ahmed   +6 more
doaj   +1 more source

IgA nephropathy – new insights into IgA nephropathy [PDF]

Liječnički vjesnik : glasilo Hrvatskoga liječničkog zbora, 2022
. Uvod: IgA nefropatija je najčešći oblik primarnog glomerulonefritisa u svijetu i značajno doprinosi nastanku kronične bolesti bubrega i završnog stadija bubrežnog zatajenja. Cilj: Prikazati nove spoznaje o IgA nefropatiji. Metode: Napravljen je pregled objavljene literature.
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