Results 71 to 80 of about 31,703 (224)
Half a century of IgA nephropathy: achievements, frustrations and challenges
Український Журнал Нефрології та Діалізу, 2018 IgA nephropathy is the most common glomerulonephritis worldwide. This disease has a tremendous economic impact because renal replacement therapy is expensive and hard-to-reach.
I.I. Lapchynska
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Medicine, 1984 We report five cases of crescentic IgA nephropathy. All are males, 16-60 years of age. One case each came to medical attention with uremia, nephrotic syndrome, and gross hematuria; two cases presented with microhematuria and proteinuria on routine urinalysis. All had hypertension, azotemia (serum creatinine 1.6-9.4 mg/dl), proteinuria (greater than 6 g/
J G, Abuelo +5 more
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Health Science Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background Diabetic nephropathy is among the most critical long‐term complications linked to diabetes, substantially influencing both morbidity and mortality. Although it was once largely associated with adults, diabetic kidney disease (DKD) has now become a leading source of kidney complications among children worldwide.
Iran Malekzadeh +6 more
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The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, Volume 2, Issue 2, June 2026.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
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Research advances on the pathogenesis of IgA nephropathy
Linchuang shenzangbing zazhi, 2022 IgA nephropathy is the most common primary glomerular disease in the world. Up to 20%-40% of patients develop end-stage renal disease within 20 years after a definite diagnosis of renal biopsy.
Lu Fang-cao, Yuan Hong-ling
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Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone
JEADV Clinical Practice, Volume 5, Issue 2, Page 415-424, June 2026.ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri +2 more
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BMC NephrologyIgA nephropathy, presently recognized as the foremost primary glomerular disorder, emerges as a principal contributor to renal failure globally, with its pathogenesis yet to be fully elucidated. Extensive research has highlighted the critical role of gut
Yitao Fan, Yan Wang, Han Xiao, Hui Sun
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Urinary uromodulin excretion predicts progression of chronic kidney disease resulting from IgA nephropathy. [PDF]
PLoS ONE, 2013 BACKGROUND: Uromodulin, or Tamm-Horsfall protein, is the most abundant urinary protein in healthy individuals. Recent studies have suggested that uromodulin may play a role in chronic kidney diseases.
Jingjing Zhou +7 more
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The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
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A case presentation of an IgA nephropathy patient with Vogt-Koyanagi-Harada syndrome
BMC Nephrology, 2020 Background Vogt-Koyanagi-Harada syndrome is a rare disease characterized by skin and eyelash bleaching, chronic granulomatous iridocyclitis and exudative retinal detachment, and aseptic meningitis and encephalopathy.
Quan Zhang +3 more
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