Results 1 to 10 of about 455,260 (321)

Regulation of B cell fate by chronic activity of the IgE B cell receptor [PDF]

eLife, 2016
IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE+ B cells are constrained by chronic activity of the IgE B cell receptor (BCR).
Zhiyong Yang, M. Robinson, Xiangjun Chen, G. A. Smith, J. Taunton, Wanli Liu, Christopher D. C. Allen   +6 more
semanticscholar   +3 more sources

Geodetic point surface mass balances: a new approach to determine point surface mass balances on glaciers from remote sensing measurements [PDF]

The Cryosphere, 2021
Mass balance observations are very useful to assess climate change in different regions of the world. As opposed to glacier-wide mass balances which are influenced by the dynamic response of each glacier, point mass balances provide a direct climatic ...
C. Vincent, D. Cusicanqui, D. Cusicanqui, B. Jourdain, O. Laarman, D. Six, A. Gilbert, A. Walpersdorf, A. Rabatel, L. Piard, F. Gimbert, O. Gagliardini, V. Peyaud, L. Arnaud, E. Thibert, F. Brun, U. Nanni   +16 more
doaj   +1 more source

Strong changes in englacial temperatures despite insignificant changes in ice thickness at Dôme du Goûter glacier (Mont Blanc area) [PDF]

The Cryosphere, 2020
The response of very-high-elevation glaciated areas on Mont Blanc to climate change has been analysed using observations and numerical modelling over the last 2 decades. Unlike the changes at low elevations, we observe very low glacier thickness changes,
C. Vincent, A. Gilbert, B. Jourdain, L. Piard, P. Ginot, V. Mikhalenko, P. Possenti, E. Le Meur, O. Laarman, D. Six   +9 more
doaj   +1 more source

A high-frequency, long-term data set of hydrology and sediment yield: the alpine badland catchments of Draix-Bléone Observatory [PDF]

Earth System Science Data, 2023
Draix-Bléone critical zone observatory was created in 1983 to study erosion processes in a mountainous badland region of the French Southern Alps. Six catchments of varying size (0.001 to 22 km2) and vegetation cover are equipped to measure water and ...
S. Klotz, C. Le Bouteiller, N. Mathys, F. Fontaine, X. Ravanat, J.-E. Olivier, F. Liébault, H. Jantzi, H. Jantzi, P. Coulmeau, D. Richard, J.-P. Cambon, M. Meunier   +12 more
doaj   +1 more source

The role of allergen‐specific IgE, IgG and IgA in allergic disease

Allergy. European Journal of Allergy and Clinical Immunology, 2021
Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease affecting more than 30% of the population. Exposure to even minute quantities of allergens can lead to the production of IgE antibodies in atopic individuals.
M. Shamji, R. Valenta, T. Jardetzky, V. Verhasselt, S. Durham, P. Würtzen, R. van Neerven   +6 more
semanticscholar   +1 more source

Photolytic modification of seasonal nitrate isotope cycles in East Antarctica [PDF]

Atmospheric Chemistry and Physics, 2022
Nitrate in Antarctic snow has seasonal cycles in nitrogen and oxygen isotopic ratios that reflect its sources and atmospheric formation processes, and as a result, nitrate archived in Antarctic ice should have great potential to record atmospheric ...
P. D. Akers, P. D. Akers, J. Savarino, N. Caillon, O. Magand, E. Le Meur   +5 more
doaj   +1 more source

Total IgE as a Marker for Chronic Spontaneous Urticaria

Allergy Asthma and Immunology Research, 2021
Objective Immunoglobulin E (IgE) and its receptor, FcɛRI, importantly contribute to the pathophysiology of chronic spontaneous urticaria (CSU). Recent findings point to a possible role of total IgE as a marker of CSU disease activity, endotypes, and ...
S. Altrichter, J. S. Fok, Q. Jiao, P. Kolkhir, Polina Pyatilova, S. Romero, J. Scheffel, F. Siebenhaar, Carolin Steinert, Dorothea Terhorst-Molawi, Yi Xiang, M. Church, M. Maurer   +12 more
semanticscholar   +1 more source

Ensemble quantification of short-term predictability of the ocean dynamics at a kilometric-scale resolution: a Western Mediterranean test case [PDF]

Ocean Science, 2022
We investigate the predictability properties of the ocean dynamics using an ensemble of short-term numerical regional ocean simulations forced by prescribed atmospheric conditions.
S. Leroux, S. Leroux, S. Leroux, J.-M. Brankart, A. Albert, A. Albert, L. Brodeau, L. Brodeau, J.-M. Molines, Q. Jamet, J. Le Sommer, T. Penduff, P. Brasseur   +12 more
doaj   +1 more source

Identification of IgE [PDF]

Journal of Allergy and Clinical Immunology, 2016
Progress in protein chemistry in the 1950s revealed that the biologic activities of proteins, such as hemoglobin and enzymes, are based on partial structures in the protein molecules. This principle suggested to us the possibility that the human antibodies responsible for induction of reaginic hypersensitivity reactions might have unique structures ...
Teruko Ishizaka, Kimishige Ishizaka
openaire   +2 more sources

MobRISK: a model for assessing the exposure of road users to flash flood events [PDF]

Natural Hazards and Earth System Sciences, 2017
Recent flash flood impact studies highlight that road networks are often disrupted due to adverse weather and flash flood events. Road users are thus particularly exposed to road flooding during their daily mobility. Previous exposure studies, however,
S. Shabou, I. Ruin, C. Lutoff, S. Debionne, S. Anquetin, J.-D. Creutin, X. Beaufils   +6 more
doaj   +1 more source