Results 101 to 110 of about 488,312 (382)

Chronic rhinosinusitis and omalizumab: eosinophils not IgE predict treatment response in real-life [PDF]

Rhinology Online, 2018
Background: Chronic rhinosinusitis with and without nasal polyps (CRSwNP and CRSsNP respectively) can be difficult to treat and biologics offer potential as a future therapeutic intervention. CRS and severe asthma often co-exist.
Jagdeep Sahota, Therese Bidder, Rebecca Livingston, Douglas S. Robinson, Valerie J. Lund, Matthew P. Su, Harsha H. Kariyawasam   +6 more
doaj   +1 more source

Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction

Nature Communications, 2018
Anti-IgE therapeutics interfere with the ability of IgE to bind to its receptors on effector cells. Here we report the crystal structure of an anti-IgE single-domain antibody in complex with an IgE Fc fragment, revealing how the antibody inhibits ...
Frederic Jabs, M. Plum, N. S. Laursen, R. K. Jensen, B. Mølgaard, M. Miehe, M. Mandolesi, M. Rauber, W. Pfützner, T. Jakob, C. Möbs, G. Andersen, E. Spillner   +12 more
semanticscholar   +1 more source

Cross-sensitization between poppy seed and buckwheat in a food-allergic patient with poppy seed anaphylaxis [PDF]

, 2006
The opium poppy, Papaver somniferum L., is the source of both poppy seeds and opium. The commercially available seeds are widely used as ingredients for various kinds of food.
Oppel, T., Thomas, P., Wollenberg, A.
core   +1 more source

MILITARY DEPLOYMENT BURN PIT EXPOSURE-INDUCED CONSTRICTIVE BRONCHIOLITIS AND IGE MEDIATED INFLAMMATION: A CASE REPORT [PDF]

, 2023
DAVID J. JOHNSON, A Myer, KYLE DEVAULT, BRANDON T RAPIER, AKHINAV RAVAL, KATE BOYLAN, JOSHUA N DANG, ALIAKSANDR RAMANIUK   +7 more
openalex   +1 more source

m1A‐Dependent TRMT6/61A‐ARG2 Axis Drives Protumorigenic Senescence by Remodeling the Tumor Microenvironment

Advanced Science, EarlyView.
Uncovering a new layer of translational control, this study reveals how TRMT6/TRMT61A‐mediated tRNA‐m1A methylation drives pro‐tumorigenic senescence in colorectal cancer. By selectively enhancing ARG2 translation, this epitranscriptomic axis triggers an NF‐κB‐dependent SASP.
Tuoyang Li, Mingzhe Huang, Jinlin Cai, Xuan Li, Yaokang Xing, Rongzhao He, Zixiao Wan, Yingguo Gan, Ziming Li, Jingrong Weng, Yumo Xie, Yuanhui Wu, Xiaoxia Liu, Xiaolin Wang, Yanxin Luo, Meijin Huang, Jinxin Lin, Huichuan Yu   +17 more
wiley   +1 more source

A Retrospective Analysis of Cases with Terra Firma-forme Dermatosis: Is It an Entity Related to Allergic Diseases?

Van Tıp Dergisi, 2019
INTRODUCTION: Terra Firma-Forme Dermatosis (TFFD) is a little-known dermatosis. The etiology is not fully known. We aimed to investigate the clinical characteristics of TFFD, accompanying diseases, and a possible connection to allergic diseases. METHODS:
Gürbüz Akçay, Emine Tuğba Alataş, Gürsoy Doğan   +2 more
doaj   +1 more source

IgE to the Mammalian Oligosaccharide Galactose-α-1,3-Galactose Is Associated With Increased Atheroma Volume and Plaques With Unstable Characteristics—Brief Report

Arteriosclerosis, Thrombosis and Vascular Biology, 2018
Objective— Emerging evidence suggests a link between coronary artery disease and type 2 immunity. We sought to test the hypothesis that IgE sensitization to the mammalian oligosaccharide galactose-&agr;-1,3-galactose (&agr;-Gal)—the target allergen of ...
Jeffrey M. Wilson, A. Nguyen, Alexander J. Schuyler, S. Commins, Angela M Taylor, T. Platts-Mills, C. McNamara   +6 more
semanticscholar   +1 more source

Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge [PDF]

, 2012
Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.
Rose, Markus A., Schubert, Ralf, Schulze, Johannes, Voss, Sandra, Zielen, Stefan, Zissler, Ulrich   +5 more
core   +2 more sources

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Streamflow Monitoring at High Temporal Resolution Based on Non‐Contact Instruments and Manually Surveyed Bathymetry in a River Prone to Bathymetric Shifts

Water Resources Research
This study presents a proof of concept of a reliable methodology for monitoring streamflow in a dynamic river of the Alps prone to bathymetric changes using non‐contact instruments.
G. Nord, S. Safdar, M. Hasanyar, K. O. Eze, R. Biron, G. Freche, H. Denis, C. Legout, A. Hauet, M. Esteves   +9 more
doaj   +1 more source