Results 41 to 50 of about 455,260 (321)

Numerical modeling of the dynamics of the Mer de Glace glacier, French Alps: comparison with past observations and forecasting of near-future evolution [PDF]

open access: yesThe Cryosphere, 2020
Alpine glaciers are shrinking and rapidly loosing mass in a warming climate. Glacier modeling is required to assess the future consequences of these retreats on water resources, the hydropower industry and risk management.
V. Peyaud   +7 more
doaj   +1 more source

Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]

open access: yes, 2011
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene   +5 more
core   +1 more source

The polymorphism rs6918289 located in the downstream region of the TREM2 gene is associated with TNF-α levels and IMT-F

open access: yesScientific Reports, 2018
Triggering receptor expressed on myeloid cells 2 (TREM2) is known for its anti-inflammatory properties during the immune response, and influences negatively on TNF-α expression levels. Genetic epidemiology studies have identified polymorphisms located in
Vesna Gorenjak   +6 more
doaj   +1 more source

Chronic allergen exposure drives accumulation of long-lived IgE plasma cells in the bone marrow, giving rise to serological memory

open access: yesScience immunology, 2020
Long-lived IgE+ plasma cells in the bone marrow confer IgE memory and produce allergen-specific IgE that can drive anaphylaxis. Locating the reservoir for IgE memory Allergic diseases persist when the immune system chronically churns out allergen ...
S. Asrat   +8 more
semanticscholar   +1 more source

A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]

open access: yes, 2004
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Carr, David   +7 more
core   +1 more source

AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer—a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI)

open access: yesClinical and Translational Allergy, 2020
Elevated serum IgE levels are associated with allergic disorders, parasitosis and specific immunologic abnormalities. In addition, epidemiological and mechanistic evidence indicates an association between IgE-mediated immune surveillance and protection ...
D. Ferastraoaru   +24 more
semanticscholar   +1 more source

Staphylococcal enterotoxin sensitization in a community-based population : a potential role in adult-onset asthma [PDF]

open access: yes, 2014
Background: Recent studies suggest that Staphylococcus aureus enterotoxin sensitization is a risk factor for asthma. However, there is a paucity of epidemiologic evidence on adult-onset asthma in community-based populations.
Bachert, Claus   +11 more
core   +2 more sources

Inferring the Basal Friction Law From Long Term Changes of Glacier Length, Thickness and Velocity on an Alpine Glacier

open access: yesGeophysical Research Letters, 2023
Basal sliding of glaciers and ice sheets remains a source of uncertainty in simulating the long‐term evolution of ice masses. In particular, the response of ice flow to changes in driving stress depends strongly on the value of the exponent m in ...
A. Gilbert   +3 more
doaj   +1 more source

Performance of lateritic concrete under environmental harsh condition [PDF]

open access: yes, 2013
This is an investigation of weathering characteristics of Laterized concrete with laterite-fine aggregate ratio as a factor. It was done with a view of ascertaining the suitability of laterite as aggregate substitutes at 0, 10, 20, 30 and 40% of fine ...
Ige, O., Ige, O.
core   +1 more source

Inhibition of IgE and IgE/anti-IgE mediated responses in mast cells by Omalizumab [PDF]

open access: yesAllergy, Asthma & Clinical Immunology, 2010
BackgroundIgE binding via the high affinity FceRI receptor modu-lates FceRI expression and cytokine production in mastcells. Antigen crosslinking of bound IgE further activatesmast cells, inducing degranulation and inflammatorymediator release. Omalizumab (Xolair; Genentech Inc)is a recombinant human monoclonal anti-IgE antibodythat prevents IgE ...
Marianna Kulka, Adriana Catalli
openaire   +2 more sources

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