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It is well‐established that food proteins, such as egg, soya, cow's milk and wheat, are detectable in breastmilk for many hours or days after ingestion. Exposure to these proteins is important to the process of developing tolerance but can also sometimes
R. Meyer+12 more
semanticscholar +1 more source
In 1919, the search began for the factor, later called reagin, that could mediate an allergy, such as allergic asthma, in sera of allergic subjects. In 1967, the fifth class of immunoglobulins, IgE, was discovered and found to be able to carry reagin activity.
openaire +3 more sources
Food allergies are defined as adverse immune responses to food proteins that result in typical clinical symptoms involving the dermatologic, respiratory, gastrointestinal, cardiovascular, and/or neurologic systems.
S. Anvari+3 more
semanticscholar +1 more source
On the Bär-Hijazi-Lott invariant for the Dirac operator and a spinorial proof of the Yamabe problem [PDF]
Let $M$ be a closed spin manifold of dimension $m\geq6$ equipped with a Riemannian metric $\ig$ and a spin structure $\sa$. Let $\lm_1^+(\tilde\ig)$ be the smallest positive eigenvalue of the Dirac operator $D_{\tilde\ig}$ on $M$ with respect to a metric $\tilde\ig$ conformal to $\ig$.
arxiv
Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement
Acute allergic symptoms are caused by allergen-induced crosslinking of allergen-specific immunoglobulin E (IgE) bound to Fc-epsilon receptors on effector cells.
Jamie M. Orengo+22 more
semanticscholar +1 more source
Diagnosing Cross‐Scale Kinetic Energy Exchanges From Two Submesoscale Permitting Ocean Models
Fine‐scale motions (
Adekunle Ajayi+6 more
doaj +1 more source
EEG–fMRI of idiopathic and secondarily generalized epilepsies [PDF]
We used simultaneous EEG and functional MRI (EEG–fMRI) to study generalized spike wave activity (GSW) in idiopathic and secondary generalized epilepsy (SGE).
Duncan, J.S.+7 more
core +1 more source
High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes
IgE B cells unmasked Immunoglobulin E (IgE) antibodies play a central role in immune responses against helminth and protozoan parasites; however, they also contribute to allergies. IgE antibodies (and the B cells generating them) are rare and thus poorly
Derek Croote+3 more
semanticscholar +1 more source
γδ T cells affect IL-4 production and B-cell tolerance [PDF]
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun+22 more
core +1 more source
IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action
The evolution of IgE in mammals added an extra layer of immune protection at body surfaces to provide a rapid and local response against antigens from the environment. The IgE immune response employs potent expulsive and inflammatory forces against local antigen provocation, at the risk of damaging host tissues and causing allergic disease.
J M, McDonnell+3 more
openaire +3 more sources