IgE Antibodies: From Structure to Function and Clinical Translation
Antibodies, 2019 Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic reactions, and their powerful effector functions activated through binding to Fc receptors FcεRI and FcεRII/CD23.
B. Sutton +3 more
semanticscholar +1 more source
A synthetic view of rainfall intensification in the West African Sahel
Environmental Research Letters, 2022 The West African Sahel has been facing for more than 30 years an increase in extreme rainfall with strong socio-economic impacts. This situation challenges decision-makers to define adaptation strategies in a rapidly changing climate.
G Chagnaud +3 more
doaj +1 more source
The SUBGLACIOR drilling probe: hydraulic considerations
Annals of Glaciology, 2021 Using significant technological breakthroughs and unconventional approaches, the goal of the in situ probing of glacier ice for a better understanding of the orbital response of climate (SUBGLACIOR) project is to advance ice core research by inventing ...
O. Alemany +9 more
doaj +1 more source
Irida-Graphene: A New 2D Carbon Allotrope [PDF]
arXiv, 2022 Several 2D carbon-based materials have been computationally designed in the last years due to the success achieved by graphene. Here, we propose a new 2D all-sp$^2$ carbon allotrope, named Irida-Graphene (IG), using a bottom-up approach. IG is composed of fused rings containing 3-6-8 carbon atoms.
arxiv
Scientific Reports, 2018 Cow’s milk allergy (CMA) is one of the earliest and most common food allergy and can be elicited by both IgE- or non-IgE-mediated mechanism. We previously described dysbiosis in children with IgE-mediated CMA and the effect of dietary treatment with ...
R. Berni Canani +11 more
semanticscholar +1 more source
Surface-layer turbulence, energy balance and links to atmospheric circulations over a mountain glacier in the French Alps [PDF]
The Cryosphere, 2017 Over Saint-Sorlin Glacier in the French Alps (45° N, 6.1° E; ∼ 3 km2) in summer, we study the atmospheric surface-layer dynamics, turbulent fluxes, their uncertainties and their impact on surface energy balance (SEB) melt estimates.
M. Litt +4 more
doaj +1 more source
Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response
Nature Immunology, 2018 IgE is an ancient and conserved immunoglobulin isotype with potent immunological function. Nevertheless, the regulation of IgE responses remains an enigma, and evidence of a role for IgE in host defense is limited. Here we report that topical exposure to
Greg Crawford +15 more
semanticscholar +1 more source
Differences in both prevalence and titre of specific immunoglobulin E among children with asthma in affluent and poor communities within a large town in Ghana. [PDF]
, 2011 Background Reports from several African countries have noted an increasing prevalence of asthma in areas of extensive urbanization. Objective To investigate the relevance of allergen-specific sensitization and body mass index (BMI) to asthma/wheezing and
Addo-Yobo, E +6 more
core +1 more source
Anti-IgE therapy for IgE-mediated allergic diseases: from neutralizing IgE antibodies to eliminating IgE+ B cells [PDF]
Clinical and Translational Allergy, 2018 Allergic diseases are inflammatory disorders that involve many types of cells and factors, including allergens, immunoglobulin (Ig)E, mast cells, basophils, cytokines and soluble mediators. Among them, IgE plays a vital role in the development of acute allergic reactions and chronic inflammatory allergic diseases, making its control particularly ...
Jia-Jie Chen +6 more
openaire +4 more sources
Challenges in interpreting allergen microarrays in relation to clinical symptoms: a machine learning approach. [PDF]
, 2013 Identifying different patterns of allergens and understanding their predictive ability in relation to asthma and other allergic diseases is crucial for the design of personalized diagnostic tools.Allergen-IgE screening using ImmunoCAP ISAC(®) assay was ...
Altmann +22 more
core +1 more source