Results 131 to 140 of about 147,857 (197)

IGF-1 from bone marrow Adipoq-lineage cells stimulates endocortical bone formation in mature female mice. [PDF]

JBMR Plus
Bertels JC, Koehnken Sawall J, Dulmovits B, Liu X, Phan A, Ji X, Song F, Thom C, Long F.   +8 more
europepmc   +1 more source

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Maternal Bacillus probiotic regulates offspring growth and immunity via spleen IGF-1/mTOR and FOXO1/IL-10 pathways. [PDF]

Sci Rep
Aldayel TS, Abdelrazek HMA, El-Fahla NA, Tawfik NM, Eltamany DA, Zeidan DW, Abbas S.   +6 more
europepmc   +1 more source

From Data to Decisions: How Machine Learning and Generative Artificial Intelligence Are Redefining Precision Medicine in Kidney Transplantation

Organ Medicine, EarlyView.
This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley   +1 more source

Effect of heat stress on growth and IGF-1 expression in synthetic broiler and native cross chicken. [PDF]

Ann Med Surg (Lond)
Sneha K, Dash SK, Kumar BVS, Dubey PP.
europepmc   +1 more source

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Impaired WNT3/IGF-1 Signaling in Dorsal Dentate Gyrus Contributes to Chronic Pain-Related Cognitive Impairment. [PDF]

CNS Neurosci Ther
An Y, Wu Y, Li X, Zhou T, Liu H, Xiao Y, Lai W, Qiu Y, Wei X.   +8 more
europepmc   +1 more source

Differences in female athlete triad risk factors between Japanese and American female runners: A comparative study

PM&R, EarlyView.
Abstract Background Differences in female athlete triad risk factors between runners from Japan and the United States have not been explored. Objective To compare the prevalence of Triad risk factors and Triad components between female Japanese and American distance runners. Design Observational, cross‐sectional.
Ana Carla C. Salamunes, Natsue Koikawa, Nancy I. Williams, Kristen J. Koltun, Maha L. Vijaya Krishnan, Yuko Sakurama, Takao Matsuda, Shihoko Suzuki, Yuji Takazawa, Mary Jane De Souza   +9 more
wiley   +1 more source

Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease. [PDF]

Alzheimers Dement
Liao W, Xuan J, Ryu WI, Bormann MK, Lee Y, Dion H, Evangelista E, Li R, Trambaiolli L, Liu J, Siegel AJ, Forester BP, Cohen BM, Sonntag KC.   +13 more
europepmc   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source