Results 261 to 270 of about 24,369,820 (336)

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Reduced IGF-1 Levels Following Clomiphene Treatment for Male Hypogonadism. [PDF]

J Endocr Soc
Mogar N, Zhang D, Heaney AP.
europepmc   +1 more source

Insulin-Like Growth Factors (IGFs) and IGF-Binding Proteins (IGFBP-1, -2 and -3) in Diabetic Pregnancy: Relationship to Macrosomia.

, 1996
Yanjun Liu, Toshio Tsushima, Satomi Minei, Mayumi Sanaka, Tamaki Nagashima, Keiko Yanagisawa, Yasue Omori   +6 more
openalex   +2 more sources

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Brain miR-137 governs growth and development via GH/IGF-1 signaling. [PDF]

BMC Biol
Liao KM, Hsu WL, Huang WY, Luo WJ, Chang JH, Yu SL, Yang PC, Su KY.   +7 more
europepmc   +1 more source

Inhibitor of DNA Binding Protein 2 (ID2) Mediates the Anti-Proliferative and Pro-Differentiation Effects of Insulin-like Growth Factor-1 (IGF-1) [PDF]

Rebecca Ssengonzi, Yuye Wang, Jiayi Zhou, Yukako Kayashima, W. H. Davin Townley-Tilson, Balaji M. Rao, Qing Ma, Nobuyo Maeda-Smithies, Feng Li   +8 more
openalex   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source

Effects of IGF1 rs6214 Polymorphism and Milk Consumption on Serum Levels of IGF-1 and GH and Body Composition. [PDF]

Metabolites
Grijalva-Avila JC, Villanueva-Fierro I, Martínez-Estrada SC, Grijalva-Avila G, Gándara-Mireles A, Rivera G, Loera-Castañeda A, Almanza-Reyes H, Patrón-Romero L, Loera-Castañeda V.   +9 more
europepmc   +1 more source

Recovery From Anorexia Nervosa: A Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source

Viral insulin/IGF-like peptides inhibit IGF-1 receptor signaling to enhance viral replication. [PDF]

Cell Rep
Chuard A, Nesarajah K, Danazumi K, Reiners K, Zhang F, Levintov L, Lubos M, Žáková L, Ruggera R, McMenamin S, Vashisth H, Jiráček J, Dimarchi R, Altindis E.   +13 more
europepmc   +1 more source