Results 281 to 290 of about 30,609,190 (316)
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The double life of the IGF-1 receptor.
Receptor, 1993The IGF-1 receptor is expressed in many cell types, and its activation by its ligands is a required step for the proliferation of many cells in vivo and in vitro. In most cells in culture, requiring more than one growth factor for growth, the IGF-1 receptor can be found in one of two different modes: in the first mode, although it is autophosphorylated
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Structural biology of insulin and IGF-1 receptors.
Novartis Foundation symposium, 2004The insulin and IGF-1 receptors are members of the superfamily of receptor tyrosine kinases (RTKs). Many of these have been implicated in human cancers due to amplification, overexpression or somatic mutations of the gene. Congenital mutations of the RTKs are implicated in a growing number of inherited syndromes.
Pierre, De Meyts +4 more
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Disrupting Insulin and IGF Receptor Function in Cancer
International Journal of Molecular Sciences, 2021Douglas Yee
exaly
Role of IGF-1 receptor in radiation response
20181 ...
Valenciano, Almudena +4 more
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Understanding IGF-II Action through Insights into Receptor Binding and Activation
Cells, 2020Nicholas Stephen Kirk, Briony Forbes
exaly
IGF and Insulin Receptor Signaling in Breast Cancer
Journal of Mammary Gland Biology and Neoplasia, 2008Francesco Frasca, Antonino Belfiore
exaly