Results 101 to 110 of about 19,264 (196)

A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours [PDF]

, 2014
Breelyn A. Wilky, Michelle A. Rudek, Shabina Roohi Ahmed, Dan Laheru, David Cosgrove, Ross C. Donehower, Barry D. Nelkin, Douglas W. Ball, L. Austin Doyle, H Chen, Xiquan Ye, Graham Bigley, Chris Womack, Nilofer S. Azad   +13 more
openalex   +1 more source

ERK Phosphorylation Is Predictive of Resistance to IGF-1R Inhibition in Small Cell Lung Cancer [PDF]

, 2013
Rebekah L. Zinn, Eric E. Gardner, Luigi Marchionni, Sara C. Murphy, Irina Dobromilskaya, Christine L. Hann, Charles M. Rudin   +6 more
openalex   +1 more source

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity

, 2008
Stanley D. Chamberlain, Anikó M. Redman, Joseph W. Wilson, Felix Deanda, J. Brad Shotwell, Roseanne Gerding, Huangshu Lei, Bin Yang, Kirk L. Stevens, Anne M. Hassell, Lisa M. Shewchuk, M. Anthony Leesnitzer, Jeffery L. Smith, Peter Sabbatini, Charity Atkins, Arthur Groy, Jason L. Rowand, Rakesh Kumar, Robert A. Mook, Ganesh S. Moorthy, Samarjit Patnaik   +20 more
openalex   +1 more source

IGF-1R Inhibitor PL225B [PDF]

, 2020
openaire   +1 more source

CaMKIIα expression in a mouse model of NMDAR hypofunction schizophrenia: Putative roles for IGF-1R and TLR4

, 2017
Olalekan M. Ogundele, Charles C. Lee
openalex   +2 more sources

IGF-1R expression is associated with HPV-negative status and adverse survival in head and neck squamous cell cancer [PDF]

, 2015
Oliver Dale, Tamara Aleksic, Ketan Shah, Chengcheng Han, Hisham Mehanna, Davy Rapozo, Jon Sheard, Paul Goodyear, Navdeep Upile, Max Robinson, Terence M. Jones, Stuart C. Winter, Valentine M. Macaulay   +12 more
openalex   +1 more source

EXPRESSIONS OF IGF-1R, EZH2, LAMININ-5 IN LEUKOPLAKIA AND ORAL SQUAMOUS CELL CARCINOMA

, 2021
Sevcihan Mutlu Güner, Semra Dölek Güler, Kıvanç Bektaş Kayhan, Filiz Namdar Pekiner, Bora Başaran, Fatma Canan Alatlı   +5 more
openalex   +2 more sources

Sorafenib inhibits tumor growth and vascularization of rhabdomyosarcoma cells by blocking IGF-1R-mediated signaling

, 2008
Wessen Maruwge
openalex   +2 more sources

Figure S5 from Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer

, 2023
Adam J. Camblin, Emily A. Pace, Sharlene Adams, Michael D. Curley, Victoria Rimkunas, Lin Nie, Gege Tan, Troy Bloom, Sergio Iadevaia, Jason Baum, Charlene Minx, Akos Czibere, Chrystal U. Louis, Daryl C. Drummond, Ulrik B. Nielsen, Birgit Schoeberl, J. Marc Pipas, Robert M. Straubinger, Vasileios Askoxylakis, Alexey A. Lugovskoy   +19 more
openalex   +1 more source

MiR-143 Targets IGF-1R to Suppress Autoimmunity in Thyroid-Associated Ophthalmopathy

, 2022
Wei Tang, Qian Lv, Xiao Huang, Yuzhen Li, JunJie Zou, Jiaoyang Zheng, Liangliang Sun, Yi Bao, Haiyan Chen, Tuo Li, Bei Zhang, Song Xue, Yan Song, Xingxing Zhang, Xiangfang Chen, Jiping Cai, Yongquan Shi   +16 more
openalex   +2 more sources