Results 261 to 270 of about 152,806 (342)

A novel role of IGFBP5 in the migration, invasion and spheroids formation induced by IGF-I and insulin in MCF-7 breast cancer cells. [PDF]

open access: yesBreast Cancer Res Treat
Rodríguez-Rojas K   +4 more
europepmc   +1 more source

Fabricating Microfluidic Co‐Cultures of Immortalized Cell Lines Uncovers Robust Design Principles for the Simultaneous Formation of Patterned, Vascularized, and Stem Cell‐Derived Adipose Tissue

open access: yesSmall, EarlyView.
Murphy et al present an optimized co‐culture protocol for immortalized cell line vasculogenesis. Here, immortalized co‐cultures form reproducible microvessel networks across 31‐days, while gradient microchips enable simultaneous mesenchymal stem cell (MSC) adipogenesis and endothelial cell (EC) vasculogenesis.
Ashley R. Murphy   +2 more
wiley   +1 more source

Nose‐to‐Brain Delivery of Acyl‐Ghrelin Peptide Gold Nanoconjugates for Treatment of Neurodegenerative Diseases

open access: yesSmall, EarlyView.
Intranasal delivery of acyl‐ghrelin using gold nanorods (AuNRs) is investigated as a strategy for treating neurodegenerative diseases. Acyl‐ghrelin is conjugated to AuNRs under optimized conditions that preserve its bioactivity and prevent nanoparticle cross‐linking.
Shunping Han   +6 more
wiley   +1 more source

Utilization of Non‐Metallic Inclusion to Induce Intragranular Acicular Ferrite Formation Contributing to “Oxide Metallurgy”: Effect of Ti/Al Content on the Microstructure Evolution

open access: yessteel research international, EarlyView.
Fine size inclusion can serve as the effective nucleation site to induce the formation of optimal microstructure, i.e. intragranular acicular ferrite (IAF). Here, the low‐alloy steels with different amounts of Ti and Al contents are prepared, and the inclusion characteristics are quantitatively investigated.
Chen Cai, Wangzhong Mu
wiley   +1 more source

Experimental investigations on the crack development in reinforced concrete members subject to uniaxial tensile strain

open access: yesStructural Concrete, EarlyView.
Abstract To investigate crack development, in particular the evolution of crack widths and crack spacing during the crack formation and stabilized cracking stage, an experimental campaign on reinforced concrete slabs under uniaxial tensile loading was conducted. The specimens were, prior to the campaign, subjected to restraint‐induced stress for 7 days,
Christopher Schmidt   +3 more
wiley   +1 more source

Cord blood levels of insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 correlate with perinatal brain development in fetal congenital heart disease

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman   +33 more
wiley   +1 more source

Insulin‐Like Growth Factor 1 Receptor Expression for Predicting PD‑1/PD‑L1 Inhibitor Response in Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Insulin‐like growth factor 1 receptor (IGF‐1R) is crucial for immunological control and the development of different types of cancer. It is still uncertain how the expression of IGF‐1R impacts hypopharyngeal squamous cell carcinoma (HPSCC) and whether it has any predictive value for prognosis.
Wen‐Jing Li   +10 more
wiley   +1 more source

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