Results 301 to 310 of about 14,093,235 (401)

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Association of Whole Blood Amino Acid and Acylcarnitine Metabolome with Anthropometry and IGF-I Serum Levels in Healthy Children and Adolescents in Germany. [PDF]

Metabolites
Jensch R, Baber R, Körner A, Kiess W, Ceglarek U, Garten A, Vogel M.   +6 more
europepmc   +1 more source

Beyond diabetes and obesity: GLP‐1 receptor agonists in disrupting the vicious cycle of metabolic dysfunction and neuroinflammation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani, Carlos A. Mandarim‐de‐Lacerda   +1 more
wiley   +1 more source

A novel role of IGFBP5 in the migration, invasion and spheroids formation induced by IGF-I and insulin in MCF-7 breast cancer cells. [PDF]

Breast Cancer Res Treat
Rodríguez-Rojas K, Cortes-Reynosa P, Torres-Alamilla P, Rodríguez-Ochoa N, Salazar EP.   +4 more
europepmc   +1 more source

Gonadulin and Insulin‐Like Growth Factor Involved in Rhipicephalus microplus Reproduction

Entomologia Experimentalis et Applicata, EarlyView.
Insulin‐like growth factor (IGF2) in ovaries of Rhipicephalus microplus partially engorged females. Ovaries from females at different feeding stages were used to detect IGF2. ABSTRACT Gonadulin and insulin‐like growth factor (IGF) are neuropeptides synthesized by the central nervous system (CNS) of arthropods.
Jéssica Waldman, Lucas Teixeira de Castro, Vinícius Andrade‐Silva, Jéssica Andrade Paes, Luís Fernando Parizi, Maria Aparecida Juliano, Saulo Petinatti Pavarini, David Driemeier, Itabajara da Silva Vaz Jr.   +8 more
wiley   +1 more source

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

Epilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe, Steeve Thirard, Juri Aparicio Arias, Leila Makrini, Florence Fauvelle, Emmanuelle Beyne, Alexandra Dauvé, Tristan Bouschet, Emmanuel Valjent, Federica Bertaso   +9 more
wiley   +1 more source

Equine experimental lameness induction models

Equine Veterinary Education, EarlyView.
Summary Equine lameness due to musculoskeletal injury remains a common and significant cause of decreased performance. While our understanding and management of lameness have improved with advanced imaging, as well as diagnostic and therapeutic progression, a need for experimental equine models of lameness remains.
A. Dockery, B. Beasley, V. J. Moorman
wiley   +1 more source

Insulin, IGF-I, and lactoferrin concentrations and yields and their associations with other components within colostrum, transition, and whole milk of primiparous and multiparous Holstein cattle. [PDF]

JDS Commun
Fischer-Tlustos AJ, Cartwright SL, Hare KS, Innes DJ, Cant JP, Tortades M, Fabregas F, Aris A, Garcia-Fruitos E, Steele MA.   +9 more
europepmc   +1 more source

Label‐free imaging of intracellular structures in living mammalian cells via external apodization phase‐contrast microscopy

The FEBS Journal, EarlyView.
External apodization phase‐contrast (ExAPC) microscopy enables label‐free visualization of diverse intracellular structures in living mammalian cells. By enhancing phase‐contrast imaging through optical apodization, ExAPC reveals fine subcellular details, such as lipid droplets and organelle contacts, without fluorescent labels.
Hiroshi Ohno, Takenori Nishimura, Kenta Kainoh, Yoshitaka Ohashi, Naoko Onodera, Mayuko Kano, Lay Nurhana Sari, Masato Masuda, Yoshiaki Tamura, Teppei Nishino, Yusuke Hayashi, Yusuke Yamamoto, Shin‐Ichiro Takahashi, Yuta Mishima, Yosuke Yoneyama, Yoshinori Takeuchi, Motohiro Sekiya, Takashi Matsuzaka, Takafumi Miyamoto, Hitoshi Shimano   +19 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source