1) Editoriale del Segretario IGF; 2) Verbale dell'Assemblea Annuale dei Soci 2007; 3) Verbali dei Consigli di Presidenza; 4) Cariche sociali biennio 2007-2009; 5) Resoconti delle attività TC-ESIS nel 2007; 6) Summer School IGF 2008; 7) Convocazione
Francesco Iacoviello
doaj +5 more sources
Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action [PDF]
We have reported previously that mutation of two conserved nonbasic amino acids (G203 and Q209) within the highly basic 201–218 region in the C-terminal domain of IGF-binding protein-5 (IGFBP-5) decreases binding to IGFs.
Clegg, R.A. +9 more
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Regulation of human fibroblast insulin-like growth factor (IGF)-binding proteins by IGF-1 and cytokines, mechanisms of action and effects upon IGF bioactivity [PDF]
PhDThe insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth and development.
Yateman, Martin Edward
core +4 more sources
The GH-IGF-I axis and breast cancer [PDF]
MD (Res)Breast cancer remains one of the most common causes of death amongst women today. Worldwide approximately 1.3 million women are diagnosed as having breast cancer every year.
Laban, Christiana
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Insulin-Like Growth Factor II (IGF-II) Is More Potent Than IGF-I in Stimulating Cortisol Secretion from Cultured Bovine Adrenocortical Cells: Interaction with the IGF-I Receptor and IGF-Binding Proteins [PDF]
Although the stimulating effect of insulin-like growth factor I (IGF-I) on adrenal steroidogenesis has been well established, the role of IGF-II in the adult adrenal gland remains unknown.
Weber, Matthias M. +4 more
core +2 more sources
Aim. To investigate the content of insulin-like growth factor (IGF)-1, IGF-2, and their transporter proteins IGFBP-1 and IGFBP in the liver of rats with experimental diabetes, Guerin’s carcinoma, and their combination.Materials and methods.
E. M. Frantsiyants +12 more
doaj +1 more source
Persistent hyperglycemia resulting from diabetes mellitus causes microvascular lesions and long-term diabetic complications, such as nephropathy.The aim of the study was to analyze the levels of insulin-like growth factors (IGFs), their carrier proteins (
E. M. Frantsiyants +9 more
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The mGlu7 receptor provides protective effects against epileptogenesis and epileptic seizures
Finding new targets to control or reduce seizure activity is essential to improve the management of epileptic patients. We hypothesized that activation of the pre-synaptic and inhibitory metabotropic glutamate receptor type 7 (mGlu7) reduces spontaneous ...
Benoit Girard +14 more
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The effect of powder peppermint on GH and IGF gene expression and hematology in Caspian roach (Rutilus caspicus) [PDF]
In recent years, the administration of medicinal herbs as growth and innate immune stimulator has been increasing in fish. In this study, the effect of peppermint powder on GH and IGF gene expression and hematology was studied In Caspian roach (Rutilus ...
Hamed Paknejad +4 more
doaj
Modeling and separate exclusion of disturbances in terrestrial observations
The technique of a separate deletion of linear and anomalous nonlinear drift of earth tides observations for diurnal and semidiurnal waves are presented.
A.M. Kutnyi, V. Pavlik, T. Babich
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