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Acta Diabetologica, 2010
The insulin-like growth factor (IGF) system plays essential role in the regulation of cell growth, proliferation and survival and affects nearly every organ system in the body. IGF-I, which has a high structural similarity to insulin, exerts growth-promoting effects, influences glucose metabolism and has neuroprotective and cardioprotective effects ...
ANNUNZIATA, Marta +2 more
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The insulin-like growth factor (IGF) system plays essential role in the regulation of cell growth, proliferation and survival and affects nearly every organ system in the body. IGF-I, which has a high structural similarity to insulin, exerts growth-promoting effects, influences glucose metabolism and has neuroprotective and cardioprotective effects ...
ANNUNZIATA, Marta +2 more
openaire +3 more sources
IGF-II, IGF-binding proteins and IGF receptors in pancreatic β-cell lines
Journal of Endocrinology, 1997The IGFs are mitogenic agents which are closely linked to regulatory processes in carbohydrate metabolism. Because limited information is available on the occurrence of the IGF system in the pancreatic β-cell milieu, we evaluated the presence of IGFs, IGF receptors, and IGF-binding proteins (IGFBPs) in the β-cell lines βTC3 and HIT T-15.
L E, Katz +5 more
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Muscle & Nerve, 2002
AbstractSemiquantitative reverse transcriptase–polymerase chain reaction (RT‐PCR) and immunohistochemistry were performed to demonstrate whether a correlation exists between insulin‐like growth factors (IGFs)—positive regulators of growth—and myostatin, a negative regulator of muscle growth.
Hakan, Kocamis +4 more
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AbstractSemiquantitative reverse transcriptase–polymerase chain reaction (RT‐PCR) and immunohistochemistry were performed to demonstrate whether a correlation exists between insulin‐like growth factors (IGFs)—positive regulators of growth—and myostatin, a negative regulator of muscle growth.
Hakan, Kocamis +4 more
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IGF, IGF receptor and overgrowth syndromes.
Pediatric endocrinology reviews : PER, 2006The insulin-like growth factors are a family of growth factors, binding proteins and receptors that are involved in normal growth as well as in a number of pathological states. Overgrowth syndromes are a group of disorders characterized by a phenotype of excessive somatic and visceral growth.
Itay, Bentov, Haim, Werner
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Molecular Genetics Microbiology and Virology (Russian version), 2017
E. P. Kopantsev +3 more
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E. P. Kopantsev +3 more
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