Beta cells to brain cells: The pivotal role of insulin and glucose metabolism in Alzheimer's disease
Common metabolic, histochemical, and molecular pathologies: Type 2 diabetes and dementia. Abstract The risk factors and neuropathologies of cognitive decline and the onset and progression of dementia‐related disorders were, until recently, obtuse. A critical predisposing factor to Alzheimer's disease (AD) that has emerged is glucose dysmetabolism.
Stanley S. Schwartz+3 more
wiley +1 more source
THE EFFECTS OF rhIGF-1 ON GH,IEF-BP3 BND IGF-BP1 CONCENTRHTIONS BND INSULIN SENSITIVITY IN ADOLESCENTS UITH INSULIN DEPENDENT DIABETES MELLITUS (IDDW) [PDF]
T D Cheethan+6 more
openalex +1 more source
Predictive value of growth hormone and insulin-like growth factor-1 axis for gestational diabetes mellitus: a prospective cohort study. [PDF]
Cui L+9 more
europepmc +1 more source
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal+2 more
wiley +1 more source
Hepatic transcriptome profiling unveils candidate genes in cattle with liver abscesses under the influence of beef genetics in dairy cattle. [PDF]
Felizari LD+5 more
europepmc +1 more source
Patterns of Teprotumumab‐Induced Hearing Dysfunction: A Systematic Review
Abstract Objective Hearing loss has been reported after administration of the monoclonal antibody teprotumumab. The purpose of this study was to review available evidence regarding the patterns of teprotumumab‐related ototoxicity. Data Sources PubMed, EMBASE, and Cochrane Library.
Kevin Wong+8 more
wiley +1 more source
Signaling by insulin-like growth factors in paralyzed skeletal muscle: rapid induction of IGF1 expression in muscle fibers and prevention of interstitial cell proliferation by IGF-BP5 and IGF-BP4 [PDF]
Pico Caroni, Corinna Schneider
openalex +1 more source
IGFBP-2 and IGF-II: Key Components of the Neural Stem Cell Niche? Implications for Glioblastoma Pathogenesis. [PDF]
Harland AJ, Perks CM.
europepmc +1 more source
Anemia and retinopathy of prematurity: A narrative review
Anemia in infants who are at greatest risk of developing severe retinopathy of prematurity is almost universal. There is plausible evidence in the literature correlating anemia with severe ROP. However, the relationship is complex, and further study is needed to better understand the potential molecular mechanisms for anemia‐associated ROP.
Minali Prasad+3 more
wiley +1 more source
IGF‐1 Receptor as the Restriction Point of the Cell Cycle [PDF]
Renato Baserga
openalex +1 more source