Results 291 to 300 of about 396,798 (411)

Alternate Day Fasting Enhances Intestinal Epithelial Function During Aging by Regulating Mitochondrial Metabolism

open access: yesAging Cell, EarlyView.
Alternate day fasting alleviates aging‐induced intestinal epithelial barrier damage by regulating mitochondrial metabolism in small intestinal stem cells. ABSTRACT With advancing age, the decline in intestinal stem cell (ISC) function can lead to a series of degenerative changes in the intestinal epithelium, a critical factor that increases the risk of
Heng Quan   +12 more
wiley   +1 more source

37 CORRELATION BETWEEN IGF-I AND STEROID LEVELS IN THE UMBILICAL CORD OF TERM NORMAL NEW (NB) [PDF]

open access: bronze, 1992
M G F Osoria   +5 more
openalex   +1 more source

Functional Equivalence of Insulin and IGF-1 in the In Vitro Culture of Chicken Primordial Germ Cells. [PDF]

open access: yesGenes (Basel)
Liu X   +10 more
europepmc   +1 more source

Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging

open access: yesAging Cell, EarlyView.
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang   +22 more
wiley   +1 more source

Senescent Macrophages Promote Age‐Related Revascularization Impairment by Increasing Antiangiogenic VEGF‐A165B Expression

open access: yesAging Cell, EarlyView.
The underlying mechanisms of age‐related revascularization impairment are not clear. Our research firstly identified that macrophages were more senescent in the ischemic skeletal muscle of old mice and senescent macrophages could inhibit revascularization.
Minghong Chen   +7 more
wiley   +1 more source

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