Results 31 to 40 of about 29,583 (184)
Příprava a charakterizace prohormonů IGF2 [PDF]
, 2022 Insulin-like growth factors 1 and 2 are protein hormones that share similar structural and functional features with insulin. They are commonly abbreviated as IGF1 and IGF2.
Potalitsyn, Pavlo
core
, 2017 Insulin-like growth factor 2 (IGF2) is a 7.5 kDa mitogenic peptide hormone expressed by liver and many other tissues. It is three times more abundant in serum than IGF1, but our understanding of its physiological and pathological roles has lagged behind
Livingstone, C
core +2 more sources
Correlation of IGF2 levels with sperm quality, inflammation, and DNA damage in infertile patients
Asian Journal of AndrologyInsulin-like growth factor 2 (IGF2) is a critical endocrine mediator implicated in male reproductive physiology. To investigate the correlation between IGF2 protein levels and various aspects of male infertility, specifically focusing on sperm quality ...
Jing-Gen Wu +8 more
doaj +1 more source
PLoS ONE, 2021 Previous studies have shown an increase of insulin-like growth factor-2 (IGF2) in animal models of neuropathic pain. We aimed to examine the hypothesis that reducing the expression of IGF2 using intrathecal IGF2 small-interfering RNA (siRNA) would ...
Wei-Hung Chan +5 more
doaj +1 more source
Hsa_circ_0003489 Drives PTX Resistance of Human NSCLC Cells Through Modulating miR-98-5p/IGF2
Pharmacogenomics and Personalized Medicine, 2023 Shaofeng Xia,1 Chenliang Wang2 1Department of Thoracic Surgery, The First People’s Hospital of Jiujiang City, Jiujiang, Jiangxi, People’s Republic of China; 2Department of Pathology, The First People’s Hospital of Jiujiang City, Jiujiang, Jiangxi, People’
Xia S, Wang C
doaj
Up-regulation of lncRNA IGF2-ASexpression promotes progression of colorectal cancer [PDF]
Jichu yixue yu linchuangObjective To investigate the expression and clinical significance of lncRNA insulin growth factor 2 antisense IGF2-AS in colorectal cancer; To verify the biological function of IGF2-AS in cells and to screen protein molecules regulated by IGF2-AS ...
CUI Lijiao, WU Xiu, GU Zhiwei, ZHOU Yu, YU Caiyuan
doaj +1 more source
eLife, 2022 Dysregulation of the imprinted H19/IGF2 locus can lead to Silver-Russell syndrome (SRS) in humans. However, the mechanism of how abnormal H19/IGF2 expression contributes to various SRS phenotypes remains unclear, largely due to incomplete understanding ...
Suhee Chang +10 more
doaj +1 more source
Dietary and supplemental maternal methyl-group donor intake and cord blood DNA methylation
Epigenetics, 2017 Maternal nutrition is critically involved in the development and health of the fetus. We evaluated maternal methyl-group donor intake through diet (methionine, betaine, choline, folate) and supplementation (folic acid) before and during pregnancy in ...
Sara Pauwels +9 more
doaj +1 more source
Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation [PDF]
, 2006 Cell-cell contact is essential for appropriate co-ordination of development and it initiates significant signalling events. During myogenesis, committed myoblasts migrate to sites of muscle formation, align and form adhesive contacts that instigate cell ...
Cobb, L.J. +8 more
core +1 more source
Cell Communication and Signaling, 2017 Background Human cancer cells often exhibit impaired IGF2 expression and the underlying mechanisms are multifaceted and complex. Besides the well-known imprinting control region IGF2/H19-ICR, the involvement of a differentially methylated region in the ...
Undraga Schagdarsurengin +7 more
doaj +1 more source