Results 121 to 130 of about 7,271 (197)

HMGA2 overexpression activates IGF2BP2 to stabilize APLP2 via m6A modification and promote pancreatic cancer progression

Pancreatic cancer is a highly aggressive malignancy of the digestive system, with occult onset, rapid progression, and poor prognosis. The genetic heterogeneity of pancreatic cancer contributes to its highly malignant biological behavior.
Congbing Wei, Haixin Yu, Zhouyuan Du, Ke Liu, Qun Zhang   +4 more
core   +1 more source

An IGF2BP2-MYBL2-HMGB2 Signaling Axis Promotes Macrophage Immune Evasion in Hepatocellular Carcinoma. [PDF]

Cancer Commun (Lond)
Ha JW, Kim SY, Jeon S, Na MJ, Yoon JH, Nam SW.   +5 more
europepmc   +1 more source

The insulin-like growth factor 2 mRNA-binding protein 2 affects tumor cell metabolism via mitochondrial transporter activity and lipid alterations. [PDF]

Cell Death Discov
Kendzia S, Franke S, Pirritano M, Grafahrend-Belau E, Köhler N, Bauchspiess T, Franzenburg S, Höring M, Raab E, Schmeier L, Sürmeli S, Erdmann F, Klose J, Kleeff J, Boettcher M, Liebisch G, Pauling JK, Simon M, Junker BH, Kessler SM.   +19 more
europepmc   +1 more source

SH2B3 Promotes PD-L1-Mediated Immune Evasion in Glioblastoma via BRCC3-Dependent IGF2BP2 Stabilization. [PDF]

Int J Biol Sci
Li R, Wang J, Meng X, Pan J, Chen X, Pan X, Li W, Qiao S, Qian L.   +8 more
europepmc   +1 more source

Molecular Characterization and Functional Insights into Goose IGF2BP2 During Skeletal Muscle Development

Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is an RNA-binding protein known to play critical roles in metabolism, cell proliferation, and tumorigenesis.
Jiuli Dai, Shufang Chen, Cui Wang, Yi Liu, Daqian He   +4 more
core   +1 more source

LncRNA GSEC impedes the reprogramming of glucose metabolism in papillary thyroid carcinoma by inhibiting the IGF2BP2/GLUT1 axis. [PDF]

Arch Endocrinol Metab
Ren L, Zhang K, Yu X, Jiang Y.
europepmc   +1 more source

CD90 mediates gastric cancer immune evasion though regulating IGF2BP2 to stabilize the m6A-CD47/SIRPα axis. [PDF]

Cancer Cell Int
Liu S, Liang L, Zhou Z, Zhang C, Liao S, He Q, Lei Y, Xu J, Luo G, Li Y, Zhou Y.   +10 more
europepmc   +1 more source

Spatial control of mRNA translation underlies MKRN3-mediated delay of puberty. [PDF]

iScience
Shalev D, Pnueli L, Argoetti A, Brent de Leon T, Golan G, Polyak G, Hashimshony T, Mandel-Gutfreund Y, Melamed P.   +8 more
europepmc   +1 more source

LncRNA-ATB Orchestrates Tumor Growth and Immune Responses Through the Modulation of IGF2BP2 in Non-Small-Cell Lung Cancer. [PDF]

IUBMB Life
Sun S, Chen H, Rong S, Li C, Zhu D, Hong E.   +5 more
europepmc   +1 more source

Single-cell and spatial transcriptomic analysis reveal distinct tumor microenvironment signatures in primary and recurrent hypopharyngeal squamous cell carcinoma. [PDF]

Cell Mol Biol Lett
Cai Z, Zhang J, Ding Y, Xu Z, Liu Z, Qiang Z, Lu Z, Chen L, Wen W, Lei W.   +9 more
europepmc   +1 more source