Results 111 to 120 of about 1,066,993 (308)

Arsenic in the groundwater aquifers of the Venetian Plain: geochemical modelling and occurrence of As-sulfides minerals, a review of data from the medio Brenta domain (Italy)

Acque Sotterranee
The Venetian Plain is known for areas with high concentrations of arsenic (As) in groundwater (up to more than 400 μg/L; exceptionally 647 μg/L, in selected areas). A study area was chosen, north of Padua, which exhibits typical residential, industrial,
Fabio Tateo, Paolo Fabbri, Maria Chiara Dalconi, Luca Peruzzo   +3 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Non-invasive detection of IgG antibodies from common pathogenic viruses using oral flocked swabs

, 2020
Salivary antibodies are useful in surveillance and vaccination studies. However, low antibody levels and degradation by endonucleases are problematic.
Smith, Emma J, Luinstra, Kathy, Smieja, Marek, Castriciano, Santina, Speicher, David J   +4 more
core   +1 more source

Pattern of IgM and IgG changes depending on the pathological process duration in patients with autoimmune thyroiditis

Zaporožskij Medicinskij Žurnal
The aim of the study was to find out the pattern of IgM and IgG changes in patients with autoimmune thyroiditis depending on the pathological process duration. Materials and methods.
R. R. Rahimova, L. Mehdiyev, G. S. Dashdamirova, S. R. Guliyeva, U. H. Azizova, F. F. Rzayeva   +5 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Pain in AQP4-IgG-positive and MOG-IgG-positive neuromyelitis optica spectrum disorders [PDF]

, 2018
Background: Pain is a frequent symptom in aquaporin-4-immunoglobulin-G-positive neuromyelitis optica spectrum disorders (AQP4-IgG-pos. NMOSD). Data on pain in myelin-oligodendrocyteglycoprotein- immunoglobulin-G autoimmunity with a clinical NMOSD ...
Chien, C., Schmidt, F., Paul, F., Bellmann-Strobl, Judith, Ruprecht, Klemens, Ruprecht, K., Bellmann-Strobl, J., Asseyer, Susanna, Chien, Claudia, Scheel, Michael, Paul, Friedemann, Brandt, A.U., Brandt, Alexander U., Asseyer, S., Schmidt, Felix, Scheel, M.   +15 more
core   +1 more source

Seroprevalence Study of Anti-HEV IgG among Different Adult Populations in Corsica, France, 2019

Microorganisms, 2019
Hepatitis E virus (HEV) is a major cause of acute hepatitis worldwide. In France, hyperendemic areas including Corsica have an anti-HEV Immunoglobulin G (IgG) prevalence higher than 50%.
Lisandru Capai, Shirley Masse, Pierre Gallian, Cécile Souty, Christine Isnard, Thierry Blanchon, Brigitte Peres, Xavier de Lamballerie, Rémi Charrel, Alessandra Falchi   +9 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Direct Immunofluorescence of IgG on Formalin-Fixed Paraffin-Embedded Tissue by Heat-Induced Antigen Retrieval as a Sensitive Method for the Diagnosis of Pemphigus

Clinical, Cosmetic and Investigational Dermatology, 2023
Wenzhe Zhao,1 Haiqin Zhu,1 Xiaoqing Zhao,1 Xinyi Wu,1 Fei Sun,1 Meng Pan,1,* Shengru Zhou2,* 1Department of Dermatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 2Department ...
Zhao W, Zhu H, Zhao X, Wu X, Sun F, Pan M, Zhou S   +6 more
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source