Results 121 to 130 of about 1,067,036 (373)

The use of quantum dots to amplify antigen detection [PDF]

open access: yesarXiv, 2017
Proposal to develop an Improved immunological assay employing primary IgG antibodies and secondary IgM antibodies labeled with quantum dots to amplify antigen detection.
arxiv  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Recurrence quantification analysis as a tool for the characterization of molecular dynamics simulations [PDF]

open access: yes, 1998
A molecular dynamics simulation of a Lennard-Jones fluid, and a trajectory of the B1 immunoglobulin G-binding domain of streptococcal protein G (B1-IgG) simulated in water are analyzed by recurrence quantification, which is noteworthy for its independence from stationarity constraints, as well as its ability to detect transients, and both linear and ...
arxiv   +1 more source

Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex–mediated immune responses

open access: yesScience Advances, 2019
Therapeutic blockade of FcRn in humans decreases IgG and IgG immune complex levels with the attendant immunologic implications. The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglobulin G ...
L. Blumberg   +24 more
semanticscholar   +1 more source

IgG Charge

open access: yes, 2018
It has been known since the 1930’s that all immunoglobulins carry a weak negative charge in physiological solvents. However, there has been no systematic exploration of this fundamental property. Accurate charge measurements have been made using membrane confined electrophoresis in two solvents (pH 5.0 and pH 7.4) on a panel of twelve mAb ...
Danlin Yang   +3 more
openaire   +2 more sources

Designing an ELISA Method for Measurement of Human IgG and IgM Antibodies against SARS-CoV-2

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Saeid Taghiloo   +3 more
doaj  

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

open access: yesFEBS Open Bio, EarlyView.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques   +5 more
wiley   +1 more source

Analysis and comparison of precise long-term nutation series, strictly determined with OCCAM 6.1 VLBI software [PDF]

open access: yesDans Journ\'ees 2005 - syst\`emes de r\'ef\'erence spatio-temporels. - Earth dynamics and reference systems: five years after the adoption of the IAU 2000 resolutions, Varsovie : Pologne (2005), 2008
The IAU/IUGG Working Group on "Nutation for a non-rigid Earth", led by V\'eronique Dehant, won the European Descartes Prize in 2003, for its work developing a new model for the precession and the nutations of the Earth. This model (MHB2000, Mathews et al.
arxiv  

CSF cytokine profile in MOG-IgG+ neurological disease is similar to AQP4-IgG+ NMOSD but distinct from MS: a cross-sectional study and potential therapeutic implications

open access: yesJournal of Neurology Neurosurgery & Psychiatry, 2018
Objective To evaluate cerebrospinal fluid (CSF) cytokine profiles in myelin oligodendrocyte glycoprotein IgG-positive (MOG-IgG+) disease in adult and paediatric patients.
K. Kaneko   +16 more
semanticscholar   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

open access: yesFEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano   +16 more
wiley   +1 more source

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