Results 121 to 130 of about 1,067,036 (373)
The use of quantum dots to amplify antigen detection [PDF]
Proposal to develop an Improved immunological assay employing primary IgG antibodies and secondary IgM antibodies labeled with quantum dots to amplify antigen detection.
arxiv
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Recurrence quantification analysis as a tool for the characterization of molecular dynamics simulations [PDF]
A molecular dynamics simulation of a Lennard-Jones fluid, and a trajectory of the B1 immunoglobulin G-binding domain of streptococcal protein G (B1-IgG) simulated in water are analyzed by recurrence quantification, which is noteworthy for its independence from stationarity constraints, as well as its ability to detect transients, and both linear and ...
arxiv +1 more source
Therapeutic blockade of FcRn in humans decreases IgG and IgG immune complex levels with the attendant immunologic implications. The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglobulin G ...
L. Blumberg+24 more
semanticscholar +1 more source
It has been known since the 1930’s that all immunoglobulins carry a weak negative charge in physiological solvents. However, there has been no systematic exploration of this fundamental property. Accurate charge measurements have been made using membrane confined electrophoresis in two solvents (pH 5.0 and pH 7.4) on a panel of twelve mAb ...
Danlin Yang+3 more
openaire +2 more sources
Designing an ELISA Method for Measurement of Human IgG and IgM Antibodies against SARS-CoV-2
Background and purpose: Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Saeid Taghiloo+3 more
doaj
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques+5 more
wiley +1 more source
Analysis and comparison of precise long-term nutation series, strictly determined with OCCAM 6.1 VLBI software [PDF]
The IAU/IUGG Working Group on "Nutation for a non-rigid Earth", led by V\'eronique Dehant, won the European Descartes Prize in 2003, for its work developing a new model for the precession and the nutations of the Earth. This model (MHB2000, Mathews et al.
arxiv
Objective To evaluate cerebrospinal fluid (CSF) cytokine profiles in myelin oligodendrocyte glycoprotein IgG-positive (MOG-IgG+) disease in adult and paediatric patients.
K. Kaneko+16 more
semanticscholar +1 more source
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano+16 more
wiley +1 more source