Results 81 to 90 of about 1,046,670 (302)

A Methodology for Assessing the Favourability of Geopressured-Geothermal Systems in Sedimentary Basin Plays: A Case Study in Abruzzo (Italy)

Geofluids, 2019
We exploit the concept of the geothermal favourability, widely used for hydrothermal and EGS systems, to present an innovative methodology for assessing geopressured-geothermal resources occurring in terrigenous units in sedimentary basin plays ...
Alessandro Santilano, Eugenio Trumpy, Gianluca Gola, Assunta Donato, Davide Scrocca, Federica Ferrarini, Francesco Brozzetti, Rita de Nardis, Giusy Lavecchia, Adele Manzella   +9 more
doaj   +1 more source

Sensitivity of rMEA-IgG-ELISA for the detection of schistosomiasis considering the classification by egg load.

, 2019
Sensitivity of rMEA-IgG-ELISA for the detection of schistosomiasis considering the classification by egg load.
Vanessa Silva-Moraes (6459683), Lisa Marie Shollenberger (6459686), Donald A. Harn (383728), Lia Carolina Soares Medeiros (180162), Liliane Maria Vidal Siqueira (3165462), Nathalie Bonatti Franco Almeida (3165459), Jose Roberto Lambertucci (6459701), Caroline Stephane Salviano Pereira (6459692), Aureo Almeida (6459698), Rafaella Fortini Queiroz Grenfell (518271), William Castro-Borges (226197), Maria Luysa Camargos Pedrosa (6459695), Nídia Francisca de Figueiredo Carneiro (3165468), Wander de Jesus Jeremias (4114681), Ana Lucia Teles Rabello (6459689), Paulo Marcos Zech Coelho (305742)   +15 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Imperative of Co-existence

Technophany
In this article I examine the problem of technique in Georges Bataille's social ontology by means of a counterpoint with Bernard Stiegler's philosophy. I will defend the following theses: 1.
Tomás Ramos Mejía
doaj   +1 more source

In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart

OncoImmunology, 2021
IgE antibodies elicit powerful immune responses, recruiting effector cells to tumors more efficiently and with greater cytotoxicity than IgG antibodies.
Francis Man, Alexander Koers, Panagiotis Karagiannis, Debra H. Josephs, Heather J. Bax, Amy E. Gilbert, Tihomir S. Dodev, Silvia Mele, Giulia Chiaruttini, Silvia Crescioli, Jitesh Chauhan, Julia E. Blower, Margaret S. Cooper, James Spicer, Sophia N. Karagiannis, Philip J. Blower   +15 more
doaj   +1 more source

Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum [PDF]

, 2001
Comparisons of immunoglobulin G (IgG) subclass responses to the major polymorphic region and to a conserved region of MSP-1 in three cohorts of African villagers exposed to Plasmodium falciparum revealed that responses to Block 2 are predominantly IgG3 ...
David R. Cavanagh, Cavanagh, D R, Cavanagh, DR, Ibrahim M. Elhassan, Elhassan, I M, Jana S. McBride, Theander, TG, Kevin Marsh, McBride, JS, Elhassan, A, Hviid, L, Khalil, E A T G, Ahmed Elhassan, Thor G. Theander, Cavanagh, David, Arnot, DE, Marsh, K, David E. Arnot, E. At Tahir G. Khalil, Khalil, EA, McBride, J S, Arnot, D E, Elhassan, IM, Theander, T G, Marsh, Kevin, Lars Hviid, Dobano, C, Carlota Dobaño, Khalil, E A   +28 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Serum IgA, IgG, IgM levels, total protein (TP), albumin (ALB) changes in elderly hip fracture patients after surgery and nutritional support [PDF]

Journal of Medical Biochemistry
Background: This study aimed to evaluate the effects of nutritional support combined with stratified nursing under delirium risk assessment on immune function and postoperative delirium in elderly hip fracture patients.
Jin Fangqin, Zhang Qin, Weng Jiangping, Pan Xuting, Dong Qinyan, Zhao Yuping   +5 more
doaj   +1 more source

IgG-mediated stimulation of IL-8 production by HTR8/SV.neo (trophoblastic cell line), and inhibition by pre-treatment with mouse anti-hTLR4 or by absorption on cardiolipin-Sepharose.

, 2018
IL-8 stimulation by IgG preparations was significantly greater (p < .0001) than other groups (ANOVA and TUKEY HSD). C: unstimulated control; IgG: cells treated with 20 ug/ml purified IgG; IgG-absorbed: cells treated with IgG (20 ug/ml) purified from sera
Harvey A. Schenkein (5728673), Ravindar R. Thomas (751216)   +1 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source