Results 61 to 70 of about 457,033 (338)

IgM, Not 7S-IgM, as Cause of Increased Serum IgM Concentrations in Goiter Patients

Experimental Biology and Medicine, 1972
Circulating concentrations of immunoglobulin-M (IgM) are increased in about half of patients with endemic or sporadic nontoxic goiter (1). In the single radial immunodiffusion technique used to test those serums (2), the diameter of the precipitin ring developed against the anti-IgM serum in the agar is proportional to the logarithm of the amount of ...
I, Radichevich, J, Morse, S C, Werner
openaire   +2 more sources

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis‐Associated Interstitial Lung Disease Risk

Arthritis Care &Research, Accepted Article.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase (MMP)‐7, and serum anti‐malondialdehyde‐acetaldehyde (anti‐MAA) antibody for RA‐associated interstitial lung disease risk stratification. Methods Using a multicenter cohort of US veterans with RA, we performed a cross‐
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Piplartine eliminates CD34 + AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling

Cell Death Discovery
Acute myeloid leukaemia (AML) is a haematological malignancy characterised by the accumulation of transformed myeloid progenitors in the bone marrow. Piplartine (PL), also known as piperlongumine, is a pro-oxidant small molecule extracted from peppers ...
Ana Carolina B. da C. Rodrigues, Suellen L. R. Silva, Ingrid R. S. B. Dias, Rafaela G. A. Costa, Maiara de S. Oliveira, Milena B. P. Soares, Rosane B. Dias, Ludmila F. Valverde, Clarissa A. G. Rocha, Emily M. Johnson, Cristina Pina, Daniel P. Bezerra   +11 more
doaj   +1 more source

Tracing the Reionization-Epoch Intergalactic Medium with Metal Absorption Lines [PDF]

, 2009
IGM metal absorption lines observed in z>6 spectra offer the opportunity to probe early feedback processes, the nature of enriching sources, and the topology of reionization.
Abel, Adelberger, Adelberger, Aguirre, Aguirre, Asplund, Barth, Becker, Becker, Becker, Benjamin D. Oppenheimer, Bouwens, Bouwens, Bouwens, Bromm, Bruzual, Bunker, Calzetti, Cen, Cen, Chabrier, Chieffi, Dalla Vecchia, Davé, Davé, Davé, Davé, Davé, Dickinson, Eikenberry, Fan, Fan, Fan, Fan, Ferland, Finlator, Finlator, Finlator, Finlator, Finlator, Fontana, Fujita, Furlanetto, Furlanetto, Gnedin, Greif, Gunn, Heger, Heger, Hinshaw, Hirschi, Hopkins, Iliev, Iliev, Kawai, Kennicutt, Kereš, Kereš, Kim, Kneib, Kristian Finlator, Lidz, Madau, Madau, Martin, Martin, Mo, Murray, Navarro, Oh, Oppenheimer, Oppenheimer, Oppenheimer, Oppenheimer, Osterbrock, Pettini, Pettini, Porciani, Portinari, Rauch, Romeel Davé, Rupke, Ryan-Weber, Ryan-Weber, Scannapieco, Schaye, Shapley, Shapley, Simcoe, Songaila, Songaila, Springel, Springel, Springel, Storrie-Lombardi, Strickland, Tegmark, Thom, Thompson, Thoul, Tornatore, Tripp, Tumlinson, Vijh, Weingartner, Wise, Woosley, Wright, Yan   +108 more
core   +3 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

L’adozione del nuovo sistema di riferimento geodetico Italiano

GEOmedia, 2012
Sulla Gazzetta Ufficiale n. 48 del 27 febbraio 2012 (supplemento ordinario n. 37) è stato pubblicato il DM con cui è stato adottato un nuovo sistema di riferimento denominato ETRF2000 (2008.0). I precedenti sistemi di riferimento, ancora in uso in Italia,
Renzo Carlucci, Renzo Maseroli, Giovanni Petrosino   +2 more
doaj  

Ru(II)-based complexes containing 2-thiouracil derivatives suppress liver cancer stem cells by targeting NF-κB and Akt/mTOR signaling

Cell Death Discovery
Cancer stem cells (CSCs) are defined as a rare population of cancer cells related to tumor initiation and maintenance. These cells are primarily responsible for tumor growth, invasion, metastasis, recurrence, and resistance to chemotherapy. In this paper,
Larissa M. Bomfim, Sara P. Neves, Amanda M. R. M. Coelho, Mateus L. Nogueira, Rosane B. Dias, Ludmila de F. Valverde, Clarissa A. G. Rocha, Milena B. P. Soares, Alzir A. Batista, Rodrigo S. Correa, Daniel P. Bezerra   +10 more
doaj   +1 more source

First third-generation CAR T cell application targeting CD19 for the treatment of systemic IgM AL amyloidosis with underlying marginal zone lymphoma [PDF]

, 2023
Felix Korell, Stefan Schönland, Anita Schmitt, Madelaine Jansen, Kiavasch M. N. Farid, Carsten Müller‐Tidow, Peter Dreger, Michael Schmitt, Ute Hegenbart   +8 more
openalex   +1 more source

Unveiling the nature of dark matter with high redshift 21 cm line experiments

, 2014
Observations of the redshifted 21 cm line from neutral hydrogen will open a new window on the early Universe. By influencing the thermal and ionization history of the intergalactic medium (IGM), annihilating dark matter (DM) can leave a detectable ...
Evoli, Carmelo, Ferrara, Andrea, Mesinger, Andrei   +2 more
core   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source