Results 71 to 80 of about 427,117 (288)

Ru(II)-based complexes containing 2-thiouracil derivatives suppress liver cancer stem cells by targeting NF-κB and Akt/mTOR signaling

Cell Death Discovery
Cancer stem cells (CSCs) are defined as a rare population of cancer cells related to tumor initiation and maintenance. These cells are primarily responsible for tumor growth, invasion, metastasis, recurrence, and resistance to chemotherapy. In this paper,
Larissa M. Bomfim, Sara P. Neves, Amanda M. R. M. Coelho, Mateus L. Nogueira, Rosane B. Dias, Ludmila de F. Valverde, Clarissa A. G. Rocha, Milena B. P. Soares, Alzir A. Batista, Rodrigo S. Correa, Daniel P. Bezerra   +10 more
doaj   +1 more source

ZIBA MIR-HOSSEINI THOUGHTS : GENDER AND PUNISHMENT FOR ADULTERY IN ISLAM

International Journal of Islamic Education, Research and Multiculturalism
Ziba Mir-Hosseini is a Muslim feminist fighter, he examines how misogynistic verses often exclude women. So far, women are considered inferior to men as superior, especially when it comes to imposing sanctions for adulterers, women are more likely to ...
Nova Yanti Maleha, Waldi Nopriansyah, Dwi Noviani   +2 more
doaj   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Hedgehog components are overexpressed in a series of liver cancer cases

Scientific Reports
Liver cancers, including hepatocellular carcinoma (HCC), are the sixth most common cancer and the third leading cause of cancer-related death worldwide, representing a global public health problem. This study evaluated nine patients with HCC.
Caroline Brandi Schlaepfer Sales, Rosane Borges Dias, Ludmila de Faro Valverde, Larissa M. Bomfim, Lais Almeida Silva, Nanashara C. de Carvalho, Jorge Luiz Andrade Bastos, Tatiana Martins Tilli, Gisele Vieira Rocha, Milena Botelho Pereira Soares, Luiz Antonio Rodrigues de Freitas, Clarissa A. Gurgel Rocha, Daniel P. Bezerra   +12 more
doaj   +1 more source

Heating the IGM by X-rays from Population III Binaries in High Redshift Galaxies

, 2014
Due to their long mean free path, X-rays are expected to have an important impact on cosmic reionization by heating and ionizing the IGM on large scales, especially after simulations have suggested that Population III stars may form in pairs at redshifts
Ahn, Kyungjin, Norman, Michael L., O'Shea, Brian W., Wise, John H., Xu, Hao   +4 more
core   +1 more source

Grip and Grasp: Lizard Claw Inspired Robotic Manipulators

Advanced Robotics Research, EarlyView.
Our study identifies the most effective lizard claw shape for use as an end effector in a bioinspired robotic manipulator. By examining key geometric features and combining them into comparative indices, the Crotaphytus collaris claw is found to be the best fit.
Hyeon Lee, Kate Douglas, Asyiah Bray, Andrea Rummel, Parvez Alam   +4 more
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

PERCEPTION OF USEFULNESS AND EASE OF INTEREST IN USING SHARIA FINTECH

I-Finance
The aim of the research is to analyze perceptions of usefulness and ease of use fintech sharia among S2 STEBIS IGM Palembang students. The population in this study were STEBIS IGM students with a total research population of 314 students and female ...
Amir Salim, Eva Susanti, Doly Nofiansyah
doaj   +1 more source

Anisotropic Outflows and IGM Enrichment

, 2006
We have designed an analytical model for the evolution of anisotropic galactic outflows. These outflows follow the path of least resistance, and thus travel preferentially into low-density regions, away from cosmological structures where galaxies form ...
Grenon, Cedric, Martel, Hugo, Pieri, Matthew M.   +2 more
core   +2 more sources

The Physical State of the Intergalactic Medium or Can We Measure Y? [PDF]

, 1995
We present an argument for a {\it lower limit} to the Compton-$y$ parameter describing spectral distortions of the cosmic microwave background (CMB). The absence of a detectable Gunn-Peterson signal in the spectra of high redshift quasars demands a high ...
Barbosa, D., Bartlett, J. G., Blanchard, A.   +2 more
core   +1 more source