Results 11 to 20 of about 84,244 (257)

Significant difference in Th1/Th2 paradigm induced by tuberculosis-specific antigens between IGRA-positive and IGRA-negative patients

open access: yesFrontiers in Immunology, 2022
False negative interferon-γ release assay (IGRA) results constitute the major dilemma for the diagnosis of tuberculosis (TB) infections. Herein, we conducted a cohort study to compare the host immunological response to TB-specific antigens between active
Qiang Li   +8 more
doaj   +2 more sources

Mycobacterial heparin-binding hemagglutinin (HBHA)-induced interferon-γ release assay (IGRA) for discrimination of latent and active tuberculosis: A systematic review and meta-analysis

open access: yesPLoS ONE, 2021
Background The Mycobacterial heparin-binding hemagglutinin (HBHA) is an important latency-associated antigen that can be used to distinguish between latent tuberculosis infection (LTBI) and active tuberculosis (ATB).
Jinhua Tang   +3 more
semanticscholar   +1 more source

Prevalence of Mycobacterium tuberculosis infection as measured by the QuantiFERON-TB Gold assay and ESAT-6 free IGRA among adolescents in Mwanza, Tanzania

open access: yesPLoS ONE, 2021
Background The prevalence of latent tuberculosis infection (LTBI) is vastly higher than that of tuberculosis (TB) disease and this enormous reservoir of individuals with LTBI impacts the global TB control strategy.
K. Jeremiah   +9 more
semanticscholar   +1 more source

Host factors associated with false negative results in an interferon‐γ release assay in adults with active tuberculosis

open access: yesHeliyon, 2023
Objective: To identify host factors associated with false-negative results of interferon-γ release tests in adults with active tuberculosis. Methods: The clinical data of 943 patients with active tuberculosis diagnosed by acid-fast smear staining ...
Quanxian Liu   +5 more
doaj   +1 more source

Screening for Tuberculosis in Health Care Workers. Experience in an Italian Teaching Hospital [PDF]

open access: yes, 2017
Health care workers (HCW) are particularly at risk of acquiring tuberculosis (TB), even in countries with low TB incidence. Therefore, TB screening in HCW is a useful prevention strategy in countries with both low and high TB incidence.
De Luca, Assunta   +8 more
core   +3 more sources

O prevladovanju estetskega nad poučnim v mladinski književnosti

open access: yesJezik in Slovstvo, 2014
Helga Glušič zagovarja stališče, da sta v kakovostni mladinski književnosti etika in estetika pomembnejši od poučnosti. V razpravah zasleduje predvsem dvoje: depedagogizacijo mladinske književnosti ter igro (njen vsebinski in/ali oblikovni element) in ...
Dragica Haramija
doaj   +1 more source

Diagnosis of childhood tuberculosis and host RNA expression in Africa [PDF]

open access: yes, 2014
Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with ...
Amelia C. Crampin   +26 more
core   +5 more sources

Interferon-gamma release assay has poor diagnostic accuracy in differentiating intestinal tuberculosis from Crohn’s disease in tuberculosis endemic areas [PDF]

open access: yesIntestinal Research, 2023
Background/Aims Intestinal tuberculosis (ITB) and Crohn’s disease (CD) frequently present with a diagnostic dilemma because of similar presentation.
Karan Sachdeva   +10 more
doaj   +1 more source

Tricks to translating TB transcriptomics. [PDF]

open access: yes, 2015
Transcriptomics and other high-throughput methods are increasingly applied to questions relating to tuberculosis (TB) pathogenesis. Whole blood transcriptomics has repeatedly been applied to define correlates of TB risk and has produced new insight into ...
Coussens, AK, Deffur, A, Wilkinson, RJ
core   +1 more source

Activity Disease in SLE Patients Affected IFN-γ in the IGRA Results

open access: yesJournal of Inflammation Research, 2020
Purpose Highly active systemic lupus erythematosus (SLE) causes a high risk of tuberculosis (TB) infection in SLE patients in Indonesia, a country in which the disease, especially extrapulmonary TB, is endemic.
Winni Maharani   +6 more
semanticscholar   +1 more source

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