Results 1 to 10 of about 116,104 (295)

Interferon-gamma release assay for screening of tuberculosis infection in children [PDF]

BMC Infectious Diseases, 2023
Background Interferon-gamma release assay (IGRA) is the main tool for the diagnosis of latent tuberculosis (TB) infection (LTBI). However, the indeterminate results were more frequent in children, and the underlying reasons were largely speculative.
Huiwen Zheng, Jing Xiao, Feina Li, Hao Chen, Deze Li, Yonghong Wang, Yajie Guo, Yuying Chen, Chen Shen   +8 more
doaj   +2 more sources

Interferon-gamma release assay performance in pulmonary and extrapulmonary tuberculosis. [PDF]

PLoS ONE, 2012
The diagnosis of tuberculosis remains difficult. This study aimed to assess performance of interferon-gamma release assay (IGRA) in diagnosis of active tuberculosis (ATB) with pulmonary and extrapulmonary involvements, and to determine the diagnostic ...
Yun Feng, Ni Diao, Lingyun Shao, Jing Wu, Shu Zhang, Jialin Jin, Feifei Wang, Xinhua Weng, Ying Zhang, Wenhong Zhang   +9 more
doaj   +4 more sources

Evaluation of SARS-CoV-2 interferon gamma release assay in BNT162b2 vaccinated healthcare workers [PDF]

PLoS ONE
To predict protective immunity to SARS-CoV-2, cellular immunity seems to be more sensitive than humoral immunity. Through an Interferon-Gamma (IFN-γ) Release Assay (IGRA), we show that, despite a marked decrease in total antibodies, 94.3% of 123 ...
Angélica Ramos, Sandra Martins, Ana Sofia Marinho, Pedro Norton, Maria João Cardoso, João Tiago Guimarães   +5 more
doaj   +4 more sources

Interferon-gamma release assay positivity in populations at high risk of TB infection [PDF]

IJTLD Open
BACKGROUND: Phase 3 TB vaccine trials are challenging in low-incidence settings due to the need for large sample sizes and extended follow-up. This global, observational study evaluated population-based interferon-gamma release assay (IGRA) status – a ...
A.F. Dagnew, L.L. Han, A. Cinar, D. Gaikwad, A.L. Garcia-Basteiro, M.T. Gler, S.R. Hadinegoro, W.A. Hanekom, J.R. Lama, M. Muyoyeta, S. Musala, V. Nduba, V.C. Rolla, T. Roy, J.S. Sutherland, S. Viegas, A. Wajja, T.M. Walker, R. Noble, L. Schlehuber, J. Sunshine, A.C. Schmidt, on behalf of the TBV02-E01 Study Group   +22 more
doaj   +2 more sources

Spontaneously regressing pulmonary tuberculosis detected by computed tomography in a patient with positive interferon‐gamma release assay [PDF]

Respirology Case Reports
Key message We present a case of pulmonary tuberculosis with a positive interferon‐gamma release assay showing spontaneous regression followed by progression of radiological findings.
Yuya Kimura, Hiroyuki Arai, Reo Tome, Kyohei Kaburaki, Shinji Sasada   +4 more
doaj   +2 more sources

IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]

, 2012
Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Fehrholz, Markus, Kramer, Boris W., Krump-Konvalinkova, Vera, Kunzmann, Steffen, Laug, Roderich, Schütze, Norbert, Speer, Christian P.   +6 more
core   +22 more sources

Pulmonary tuberculosis and management of contact patients in a Department of Nephrology and Kidney Transplantation

International Journal of Infectious Diseases, 2022
Objectives: To describe the investigation, follow-up, management, and outcomes in a cohort of chronic kidney disease (CKD) and kidney transplant recipients (KTR) exposed to a case of pulmonary tuberculosis (TB).
Laure Burguet, Alexandre Duvignaud, Duc Nguyen, Marie-Catherine Receveur, Hannah Kaminski, Isabelle Pellegrin, Anne-Marie Rogues, Olivia Peuchant, Karine Moreau, Pierre Merville, Lionel Couzi   +10 more
doaj   +1 more source

Novel approach to activity evaluation for release-active forms of anti-interferon-gamma antibodies based on enzyme-linked immunoassay. [PDF]

PLoS ONE, 2014
Selection of a suitable assay to measure the activity of drug agents based on release-active forms of anti-interferon-gamma antibodies (RA forms of Abs) is an important step forward in the investigation of such agents.
Elena S Gavrilova, Sergey A Bobrovnik, Gordon Sherriff, Andrey A Myslivets, Sergey A Tarasov, Oleg I Epstein   +5 more
doaj   +1 more source

Humoral and Cellular Immunity to Severe Acute Respiratory Syndrome Coronavirus-2 Vaccination in Patients with Sarcoidosis

Balkan Medical Journal, 2023
Background: The coronavirus disease 2019 vaccine induces both antibody and T-cell immune responses and has been proven to be effective in preventing coronavirus disease 2019, including its severe disease form, in healthy individuals. However, the details
Ersan Atahan, Buket Çalışkaner Öztürk, Rüveyda Akçin, Suat Sarıbaş, Bekir Kocazeybek   +4 more
doaj   +1 more source

Interferon-gamma release assay: use and misuse [PDF]

Clinical Microbiology and Infection, 2012
Interferon-gamma release assays are being increasingly used worldwide for the diagnosis of latent tuberculosis (TB) in patients of all ages, including children [1]. A PubMed search with ‘interferon-gamma release assays’ as keyword revealed a total of 1077 references, up to 100 of which had been released in 2012, including several reviews.
Brouqui, P., Delaigue, S., Parola, P., Drancourt, M.   +3 more
openaire   +2 more sources