Results 41 to 50 of about 55,486 (297)

Role of interferon gamma release assay in active TB diagnosis among HIV infected individuals. [PDF]

open access: yesPLoS ONE, 2009
A rapid and specific test is urgently needed for tuberculosis (TB) diagnosis especially among human immunodeficiency virus (HIV) infected individuals.
Basirudeen Syed Ahamed Kabeer   +5 more
doaj   +1 more source

Capturing Recent Mycobacterium tuberculosis Infection by Tuberculin Skin Test vs. Interferon-Gamma Release Assay. [PDF]

open access: yesTrop Med Infect Dis
Reductions in tuberculosis (TB) incidence require identification of individuals at high risk of developing active disease, such as those with recent Mycobacterium tuberculosis (Mtb) infection. Using a prospective household contact (HHC) study in Kampala,
Gutierrez J   +7 more
europepmc   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Comparisons of progression of tuberculosis in HIV-infected patients with interferon-gamma release assay testing.

open access: yes, 2015
Note:1Patient No.: patient number after exclusion of patients with active TB at enrollment;2TB cases, cases of patients with positive IGRA results who developed TB during follow-up;3 The incidence rate of patients with positive IGRA results who developed
Hsin-Yun Sun (61134)   +6 more
core   +1 more source

Tuberculosis in Children: New diagnostic Blood Tests

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2010
The interferon-gamma-release assays were developed to overcome the pitfalls and logistic difficulties of the tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection (LTBI).
F Kakkar   +4 more
doaj   +1 more source

Four Patients with COVID-19 and Tuberculosis, Singapore, April–May 2020

open access: yesEmerging Infectious Diseases, 2020
Coronavirus disease (COVID-19) and tuberculosis (TB) developed in 4 foreign workers living in dormitories in Singapore during April–May 2020. Clinical manifestations and atypical radiographic features of COVID-19 led to the diagnosis of TB through ...
Sai Meng Tham   +9 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Use of Interferon Gamma Release Assays in the Diagnosis of Active Tuberculosis [PDF]

open access: yesTuberculosis Research and Treatment, 2012
Interferon gamma release assays (IGRAs) arein vitroimmunologic diagnostic tests used to identifyMycobacterium tuberculosisinfection. They cannot differentiate between latent and active infections. The cutoff suggested by the manufacturer is 0.35 IU/mL for latent tuberculosis. As IGRA tests were recently approved for the differential diagnosis of active
Vesenbeckh, Silvan M.   +6 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Baseline characteristics stratified by TST status. TST tuberculin skin; N sample size; IGRA interferon gamma release assay; TB tuberculosis.

open access: yes, 2013
Baseline characteristics stratified by TST status. TST tuberculin skin; N sample size; IGRA interferon gamma release assay; TB tuberculosis.
Tom H. M. Ottenhoff (160303)   +9 more
core   +1 more source

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