Results 51 to 60 of about 55,486 (297)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Use of interferon gamma release assay to assess latent tuberculosis infection among healthcare workers in Hong Kong [PDF]

, 2015
Key Messages 1. Overall baseline interferon gamma release assay positivity was 20.7%. 2. The conversion to interferon gamma release assay positivity at 3 months was 8.85% in the exposed group and 4.54% in the non-exposed group using the conventional ...
Yam, WC, Chu, CM, Lam, BHS, Mok, YW, Chan, JWM, Seto, WH, Fung, SC, Lai, CKC, Ng, TK, Tsang, DNC   +9 more
core  

Comparison of interferon-gamma release assay versus tuberculin skin test for tuberculosis screening in inflammatory bowel disease

, 2008
OBJECTIVES: Reactivation of latent tuberculosis (TB) in inflammatory bowel disease (IBD) patients treated with antitumor necrosis factor-alpha medication is a serious problem. Currently, TB screening includes chest x-rays and a tuberculin skin test (TST).
Fallegger, Silvia, Schaffer, Thomas, Mueller, Stefan, Nicod, Laurent, Schoepfer, Alain M, Seibold, Frank, Flogerzi, Beatrice   +6 more
core   +1 more source

Multicenter clinical evaluation of three commercial reagent kits based on the interferon-gamma release assay for the rapid diagnosis of tuberculosis in China

International Journal of Infectious Diseases, 2015
Objective: To evaluate the performance of three interferon-gamma release assay (IGRA) kits in detecting Mycobacterium tuberculosis infection in China.
Yan Qiu, Yansen Wang, Nan Lin, Mingxiang Huang, Yunhong Tan, Qing Wang, Yi Jiang, Haican Liu, Jiao Liu, Jingrui Zhang, Jue Wang, Xinchan Chen, Dongping Wang, Guilian Li, Zhongnan Chen, Lishui Zhang, Dixun Bao, Lili Zhao, Chaxiang Guan, Kanlgin Wan   +19 more
doaj   +1 more source

Tuberculin test versus interferon gamma release assay in pregnant women with household contacts of tuberculosis patients

International Journal of Mycobacteriology, 2022
Background: Pregnant women who live in tuberculosis (TB)-affected households are more likely to develop latent TB infection (LTBI), which often escapes treatment.
Maisuri Tadjuddin Chalid, Dian Puspawaty, Andi Mardiah Tahir, Hidayah Najdah, Muhammad Nasrum Massi   +4 more
doaj   +1 more source

Short-Term Reproducibility of a Commercial Interferon Gamma Release Assay [PDF]

Clinical and Vaccine Immunology, 2009
ABSTRACT Interferon gamma release assays (IGRAs) have been shown to be sensitive and highly specific for the detection of immune memory against Mycobacterium tuberculosis . Little is known about the reproducibility and within-person variability of these assays. Various aspects of short-term reproducibility
A K, Detjen, L, Loebenberg, H M S, Grewal, K, Stanley, A, Gutschmidt, C, Kruger, N, Du Plessis, M, Kidd, N, Beyers, G, Walzl, A C, Hesseling   +10 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The Role of Interferon-Gamma Release Assay in Tuberculosis Control

, 2012
Tuberkuloza je i danas jedan od vodećih javnozdravstvenih problema. Zemlje s niskom incidencijom fokusiraju se na iscrpljivanje rezervoara budućih slučajeva sprječavanjem reaktivacije bolesti.
Gudelj, Ivan, Jurčev-Savičević, Anamarija, Vera Katalinić-Janković, Miše, Kornelija, Kornelija Miše, Anamarija Jurčev-Savičević, Ivan Gudelj, Katalinić-Janković, Vera   +7 more
core   +2 more sources

Rapid Decline of IFN-γ Spot-Forming Cells in Pleural Lymphocytes during Treatment in a Patient with Suspected Tuberculosis Pleurisy

Reports, 2019
A differential diagnosis of tuberculosis pleurisy is often difficult. A 48-year-old Japanese man with no previous medical history visited the outpatient department for dyspnea and fever.
Osamu Usami, Haorile Chagan Yasutan, Toshio Hattori, Yugo Ashino   +3 more
doaj   +1 more source

Performance of interferon-γ release assay in the diagnosis of tuberculous lymphadenitis: a meta-analysis [PDF]

PeerJ, 2017
Background The diagnostic values of interferon-gamma release assays (IGRA) in tuberculosis (TB) vary a lot with different site of infections, with especially higher sensitivities in chronic forms of TB such as tuberculosis of the lymph node. We conducted
Qianqian Liu, Wenzhang Li, Yunfeng Chen, Xinmiao Du, Chengdi Wang, Binmiao Liang, Yin Tang, Yulin Feng, Chuanmin Tao, Jian-Qing He   +9 more
doaj   +2 more sources