Results 51 to 60 of about 116,104 (295)

Short-Term Reproducibility of a Commercial Interferon Gamma Release Assay [PDF]

Clinical and Vaccine Immunology, 2009
ABSTRACT Interferon gamma release assays (IGRAs) have been shown to be sensitive and highly specific for the detection of immune memory against Mycobacterium tuberculosis . Little is known about the reproducibility and within-person variability of these assays. Various aspects of short-term reproducibility
A K, Detjen, L, Loebenberg, H M S, Grewal, K, Stanley, A, Gutschmidt, C, Kruger, N, Du Plessis, M, Kidd, N, Beyers, G, Walzl, A C, Hesseling   +10 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Multicenter clinical evaluation of three commercial reagent kits based on the interferon-gamma release assay for the rapid diagnosis of tuberculosis in China

International Journal of Infectious Diseases, 2015
Objective: To evaluate the performance of three interferon-gamma release assay (IGRA) kits in detecting Mycobacterium tuberculosis infection in China.
Yan Qiu, Yansen Wang, Nan Lin, Mingxiang Huang, Yunhong Tan, Qing Wang, Yi Jiang, Haican Liu, Jiao Liu, Jingrui Zhang, Jue Wang, Xinchan Chen, Dongping Wang, Guilian Li, Zhongnan Chen, Lishui Zhang, Dixun Bao, Lili Zhao, Chaxiang Guan, Kanlgin Wan   +19 more
doaj   +1 more source

Tuberculin test versus interferon gamma release assay in pregnant women with household contacts of tuberculosis patients

International Journal of Mycobacteriology, 2022
Background: Pregnant women who live in tuberculosis (TB)-affected households are more likely to develop latent TB infection (LTBI), which often escapes treatment.
Maisuri Tadjuddin Chalid, Dian Puspawaty, Andi Mardiah Tahir, Hidayah Najdah, Muhammad Nasrum Massi   +4 more
doaj   +1 more source

Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro [PDF]

, 2013
Peer reviewedPublisher ...
Pappalardo, A., Thompson, K.
core   +1 more source

Effective Tuberculosis Contact Investigation Using Interferon-Gamma Release Assays

Pediatric Infectious Disease Journal, 2019
During 2000 to 2018, 1831 children were screened as part of tuberculosis contact investigation at the Stockholm Northern Clinic. The risk of a child having a positive tuberculin skin test was 33% and positive interferon-gamma release assay 12%. The risk of tuberculosis disease was 6.1% (tuberculin skin test) and 13% (interferon-gamma release assay) in ...
Rutger, Bennet, Sahar, Nejat, Margareta, Eriksson   +2 more
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Rapid Decline of IFN-γ Spot-Forming Cells in Pleural Lymphocytes during Treatment in a Patient with Suspected Tuberculosis Pleurisy

Reports, 2019
A differential diagnosis of tuberculosis pleurisy is often difficult. A 48-year-old Japanese man with no previous medical history visited the outpatient department for dyspnea and fever.
Osamu Usami, Haorile Chagan Yasutan, Toshio Hattori, Yugo Ashino   +3 more
doaj   +1 more source

Serial Interferon-Gamma Release Assay (IGRA) Testing to Monitor Treatment Responses in Cases of Feline Mycobacteriosis

Pathogens, 2021
The interferon-gamma release assay (IGRA) is used to diagnose cases of feline mycobacteriosis, but the use of serial testing to monitor treatment responses has not been evaluated in this species.
Jordan L. Mitchell, Conor O’Halloran, Paul Stanley, Kieran McDonald, Paul Burr, Danièlle A. Gunn-Moore, Jayne C. Hope   +6 more
doaj   +1 more source

Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor [PDF]

, 1994
We have shown previously that the antiviral function of CD4+ T lymphocytes against murine cytomegalovirus (MCMV) is associated with the release of interferon- (IFN-).
Hengel, Hartmut, Jonjic, Stipan, Koszinowski, Ulrich H., Lucin, Pero, Messerle, Martin, Polic, Bojan   +5 more
core   +3 more sources