Results 31 to 40 of about 55,486 (297)

Interferon-Gamma Release Assay is Not Appropriate for the Diagnosis of Active Tuberculosis in High-Burden Tuberculosis Settings: A Retrospective Multicenter Investigation

Chinese Medical Journal, 2018
Background: Interferon-gamma release assay (IGRA) has been used in latent tuberculosis (TB) infection and TB diagnosis, but the results from different high TB-endemic countries are different.
Wan-Li Kang, Gui-Rong Wang, Mei-Ying Wu, Kun-Yun Yang, A Er-Tai, Shu-Cai Wu, Shu-Jun Geng, Zhi-Hui Li, Ming-Wu Li, Liang Li, Shen-Jie Tang   +10 more
doaj   +1 more source

Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2

Frontiers in Immunology, 2023
In search for immunological correlates of protection against acute coronavirus disease 2019 (COVID-19) there is a need for high through-put assays for cell-mediated immunity (CMI) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Luís Fonseca Brito, Luís Fonseca Brito, Silvia Tödter, Julian Kottlau, Kathrin Cermann, Anthea Spier, Elina Petersen, Elina Petersen, Ines Schäfer, Ines Schäfer, Raphael Twerenbold, Raphael Twerenbold, Raphael Twerenbold, Martin Aepfelbacher, Marc Lütgehetmann, Felix R. Stahl, Felix R. Stahl   +16 more
doaj   +1 more source

Predictors of interferon-gamma release assay results and their association with COVID-19 infection outcomes. [PDF]

IJTLD Open
BACKGROUND: An ‘indeterminate’ interferon-gamma release assay (IGRA) result used in the diagnosis of latent TB infection (LTBI) is most commonly due to an inadequate control (or ‘mitogen’) response, which may reflect underlying T-cell dysfunction ...
Kang SJW, Eather GW, Qureshi F, Scott JR.   +3 more
europepmc   +2 more sources

Interferon-gamma release assays in tuberculous uveitis: a comprehensive review

International Journal of Ophthalmology, 2022
Tuberculous uveitis (TBU) comprises a broad clinical spectrum of ocular manifestations, making its diagnosis challenging. Ophthalmologists usually require evidence from investigations to confirm or support a clinical diagnosis of TBU. Since direct isolation of the causative organism from ocular specimens has limitations owing to the small volume of the
Usanee Tungsattayathitthan, Sutasinee Boonsopon, Nattaporn Tesavibul, Tararaj Dharakul, Pitipol Choopong   +4 more
openaire   +3 more sources

Frequency of hypovitaminosis d in patients with uveitis presenting at a tertiary care hospital in a low-middle-income country

Journal of the Pakistan Medical Association
Objective: To determine the frequency of hypovitaminosis D in patients with uveitis, and to analyse its association with gender and interferon-gamma release assay status. Method: The retrospective, cross-sectional study was conducted in September 2021
Sehrish Nizar Ali Momin, Muhammad Bilal Malik, Haroon Tayyab, Muhammad Irfan, Muhammad Abdul Rehman Siddiqui   +4 more
doaj   +1 more source

In Vitro Release of Interferon-Gamma from Peripheral Blood Lymphocytes in Cutaneous Adverse Drug Reactions

Clinical and Developmental Immunology, 2012
Background. Cutaneous drug reactions are common but diagnostically challenging due to phenotypic heterogeneity and simultaneous exposure to multiple drugs. These limitations prompted the development of diagnostic tests. Aims.
Ilan Goldberg, Meital Hanson, Gabriel Chodick, Idit Shirazi, Sarah Brenner   +4 more
doaj   +1 more source

Positivity of interferon-gamma release assay among foreign-born individuals, Tokyo, Japan, 2015–2017

International Journal of Mycobacteriology, 2020
Background: The aim of this study is to analyze interferon-gamma release assay (IGRA) data of foreign-born individuals in Japan derived from tuberculosis (TB) contact investigations.
Satoshi Miyake, Masayuki Endo, Keiko Ikedo, Aya Kayebeta, Ikumi Takahashi, Masaki Ota   +5 more
doaj   +1 more source

Interferon-Gamma Release Assay in a Patient with Tuberculosis Verrucosa Cutis [PDF]

Annals of Dermatology, 2015
Dear Editor: A 62-year-old man presented with an annular plaque that had been present for 35 years on his left inner thigh. Physical examination revealed a 7×8 cm annular erythematous plaque with central clearing and hyperpigmentation (Fig. 1). We suspected tinea cruris, granuloma annulare, and erythema annulare centrifugum, and performed a 4-mm ...
Kim, Geon, Jeong, Young-In, Huh, Joon Won, Kim, Eun-Jung, Joh, Ok-Ja   +4 more
openaire   +2 more sources

Factors Associated with a Positive Interferon-Gamma Release Assay (IGRA) Result in 741 Participants^*.

, 2015
BCG, Bacille-Calmette Guérin; CI, confidence interval; HIV, human immunodeficiency virus; IDU, injection drug users. OR, odds ratio; TB, tuberculosis*Excluding 31 subjects with indeterminate interferon-gamma release assay result.†Adjusted for age, sex ...
Hsi-Hsun Lin (473561), Kuan-Sheng Wu (784205), Hsin-Yun Sun (61134), Jui-Kuang Chen (784206), Susan Shin-Jung Lee (784202), Chien-Chin Hung (784203), Ih-Jen Su (87501), Chi-Tai Fang (125570), Chin-Hui Yang (450823), Hung-Chin Tsai (673178), Yao-Shen Chen (139714), Cheng-Len Sy (784204)   +11 more
core   +1 more source

QuantiFERON®-TB gold in-tube performance for diagnosing active tuberculosis in children and adults in a high burden setting. [PDF]

, 2012
To determine whether QuantiFERON®-TB Gold In-Tube (QFT) can contribute to the diagnosis of active tuberculosis (TB) in children in a high-burden setting and to assess the performance of QFT and tuberculin skin test (TST) in a prospective cohort of TB ...
Rose, Michala Vaaben, Godfather Kimaro (151409), Kimaro, Godfather, Thomas N Nissen, Pernille Ravn (94667), Bygbjerg Ib C., Kimaro Godfather, Godfather Kimaro, Hoelscher, Michael, Rose, Michala V., Nissen, Thomas N, Rose, Michala V, Michael Hoelscher, Hoelscher Michael, Ravn, Pernille, Michael Hoelscher (151418), Ib C. Bygbjerg (151419), Nissen, Thomas N., Kroidl, Inge, Michala V Rose, Inge Kroidl, Sayoki G Mfinanga, Nissen Thomas N., Kroidl Inge, Bygbjerg, Ib C., Mfinanga Sayoki G., Michala V. Rose (151403), Ravn Pernille, Rose Michala V., Mfinanga, Sayoki G., Ib C Bygbjerg, Inge Kroidl (151415), Sayoki G. Mfinanga (151420), Mfinanga, Sayoki G, Thomas N. Nissen (151412), Pernille Ravn, Bygbjerg, Ib C   +36 more
core   +1 more source