Results 31 to 40 of about 116,104 (295)

Interferon-Gamma Release Assay is Not Appropriate for the Diagnosis of Active Tuberculosis in High-Burden Tuberculosis Settings: A Retrospective Multicenter Investigation

Chinese Medical Journal, 2018
Background: Interferon-gamma release assay (IGRA) has been used in latent tuberculosis (TB) infection and TB diagnosis, but the results from different high TB-endemic countries are different.
Wan-Li Kang, Gui-Rong Wang, Mei-Ying Wu, Kun-Yun Yang, A Er-Tai, Shu-Cai Wu, Shu-Jun Geng, Zhi-Hui Li, Ming-Wu Li, Liang Li, Shen-Jie Tang   +10 more
doaj   +1 more source

Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2

Frontiers in Immunology, 2023
In search for immunological correlates of protection against acute coronavirus disease 2019 (COVID-19) there is a need for high through-put assays for cell-mediated immunity (CMI) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Luís Fonseca Brito, Luís Fonseca Brito, Silvia Tödter, Julian Kottlau, Kathrin Cermann, Anthea Spier, Elina Petersen, Elina Petersen, Ines Schäfer, Ines Schäfer, Raphael Twerenbold, Raphael Twerenbold, Raphael Twerenbold, Martin Aepfelbacher, Marc Lütgehetmann, Felix R. Stahl, Felix R. Stahl   +16 more
doaj   +1 more source

Frequency of hypovitaminosis d in patients with uveitis presenting at a tertiary care hospital in a low-middle-income country

Journal of the Pakistan Medical Association
Objective: To determine the frequency of hypovitaminosis D in patients with uveitis, and to analyse its association with gender and interferon-gamma release assay status. Method: The retrospective, cross-sectional study was conducted in September 2021
Sehrish Nizar Ali Momin, Muhammad Bilal Malik, Haroon Tayyab, Muhammad Irfan, Muhammad Abdul Rehman Siddiqui   +4 more
doaj   +1 more source

In Vitro Release of Interferon-Gamma from Peripheral Blood Lymphocytes in Cutaneous Adverse Drug Reactions

Clinical and Developmental Immunology, 2012
Background. Cutaneous drug reactions are common but diagnostically challenging due to phenotypic heterogeneity and simultaneous exposure to multiple drugs. These limitations prompted the development of diagnostic tests. Aims.
Ilan Goldberg, Meital Hanson, Gabriel Chodick, Idit Shirazi, Sarah Brenner   +4 more
doaj   +1 more source

Positivity of interferon-gamma release assay among foreign-born individuals, Tokyo, Japan, 2015–2017

International Journal of Mycobacteriology, 2020
Background: The aim of this study is to analyze interferon-gamma release assay (IGRA) data of foreign-born individuals in Japan derived from tuberculosis (TB) contact investigations.
Satoshi Miyake, Masayuki Endo, Keiko Ikedo, Aya Kayebeta, Ikumi Takahashi, Masaki Ota   +5 more
doaj   +1 more source

Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells. [PDF]

, 2016
Natural killer (NK) cells are functionally suppressed in the glioblastoma multiforme (GBM) tumor microenvironment. We have recently shown that survival and differentiation of cancer stem-like cells (CSCs)/poorly differentiated tumors are controlled ...
Bui, Vickie T, Cacalano, Nicholas, Inagaki, Akihito, Jewett, Anahid, Kasahara, Noriyuki, Kaur, Kawaljit, Kozlowska, Anna K, Topchyan, Paytsar, Tseng, Han-Ching   +8 more
core   +1 more source

Interferon-gamma release assays in tuberculous uveitis: a comprehensive review

International Journal of Ophthalmology, 2022
Tuberculous uveitis (TBU) comprises a broad clinical spectrum of ocular manifestations, making its diagnosis challenging. Ophthalmologists usually require evidence from investigations to confirm or support a clinical diagnosis of TBU. Since direct isolation of the causative organism from ocular specimens has limitations owing to the small volume of the
Usanee Tungsattayathitthan, Sutasinee Boonsopon, Nattaporn Tesavibul, Tararaj Dharakul, Pitipol Choopong   +4 more
openaire   +3 more sources

Role of interferon gamma release assay in active TB diagnosis among HIV infected individuals. [PDF]

PLoS ONE, 2009
A rapid and specific test is urgently needed for tuberculosis (TB) diagnosis especially among human immunodeficiency virus (HIV) infected individuals.
Basirudeen Syed Ahamed Kabeer, Rajasekaran Sikhamani, Sowmya Swaminathan, Venkatesan Perumal, Paulkumaran Paramasivam, Alamelu Raja   +5 more
doaj   +1 more source

Use of interferon gamma release assay to assess latent tuberculosis infection among healthcare workers in Hong Kong [PDF]

, 2015
Key Messages 1. Overall baseline interferon gamma release assay positivity was 20.7%. 2. The conversion to interferon gamma release assay positivity at 3 months was 8.85% in the exposed group and 4.54% in the non-exposed group using the conventional ...
Chan, JWM, Chu, CM, Fung, SC, Lai, CKC, Lam, BHS, Mok, YW, Ng, TK, Seto, WH, Tsang, DNC, Yam, WC   +9 more
core  

Diagnostic Utility of Interferon-Gamma Release Assay in Tuberculous Lymphadenitis [PDF]

Chinese Medical Sciences Journal, 2019
Objective The aim of this study was to evaluate the diagnostic performance of T-SPOT.TB for tuberculous lymphadenitis. Methods Suspected tuberculous lymphadenitis patients between September 2010 and September 2018 who had both peripheral blood T-SPOT.TB test and lymph node biopsy were retrospectively enrolled in this study.
Xin-Chao, Liu, Su-Su, Ye, Wen-Ze, Wang, Yue-Qiu, Zhang, Li-Fan, Zhang, Xiao-Cheng, Pan, Zi-Yue, Zhou, Miao-Yan, Zhang, Jiang-Hao, Liu, Zhi-Yong, Liang, Xiao-Qing, Liu   +10 more
openaire   +2 more sources