Results 21 to 30 of about 116,104 (295)

Screening for Tuberculosis in Health Care Workers. Experience in an Italian Teaching Hospital [PDF]

, 2017
Health care workers (HCW) are particularly at risk of acquiring tuberculosis (TB), even in countries with low TB incidence. Therefore, TB screening in HCW is a useful prevention strategy in countries with both low and high TB incidence.
De Luca, Assunta, DI NINNO, Filippo, Ferretti, Filippo, Marani, Alessandra, Napoli, Christian, Orioli, Riccardo, Orsi, Giovanni Battista, Prestigiacomo, Claudio, Sarlo, MARIA GIUDITTA   +8 more
core   +7 more sources

Tuberculosis screening in multiple sclerosis: effect of disease-modifying therapies and lymphopenia on the prevalence of indeterminate TB screening results in the clinical setting

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2019
Background Tuberculosis screening is recommended in multiple sclerosis patients starting certain disease-modifying therapies. Disease-modifying therapies may affect interferon-gamma release assay results.
Laura E Baldassari, Jenny Feng, Gabrielle Macaron, Sarah M Planchon, Ebtesam Alshehri, Brandon P Moss, Daniel Ontaneda, Mary A Willis   +7 more
doaj   +1 more source

The evolution and role of interferon gamma release assays (IGRAs) in moderate and low income settings.

Sri Lankan Journal of Infectious Diseases, 2014
The interferon gamma release assays have been extensively evaluated in the diagnosis of latent tuberculosis infection as well as in diagnosis of active pulmonary and extra-pulmonary tuberculosis since their introduction just over a decade ago.
C N Ratnatunga
doaj   +1 more source

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]

, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari, Alimuddin Zumla, Armand, Axelsson-Robertson, Banada, Ben Marais, Betsou, Blakemore, Boehme, Boehme, Cattamanchi, Chow, Cuevas, Cuevas, Cuevas, Cuevas, Diel, Dowdy, Dye, European Centre for Disease Prevention and Control, Ferrara, Giovanni-Batista Migliori, Giuseppe Pantaleo, Green, Harari, Helb, Helen Cox, Hillemann, Hohn, Ibrahim Abubakar, Jeremiah Chakaya, John, Justin O’Grady, Karin Weyer, Keeler, Kemp, Kunnath-Velayudhan, Lawn, Lawn, Lawn, Lawn, Lawn, Lemaire, Lin, Ling, Liu, Long, Lucica Ditui, Lynn Zijenah, Mann, Marais, Marais, Marais, Marais, Marco Schito, Markus Maeurer, Marlowe, Martin P. Grobusch, Martina Casenghi, Matthew Bates, McNerney, Michael Hoelscher, Michel Pletschette, Minion, Moore, Morris, Mwaba, Nathan Ford, Nathanson, National Institute for Health and Clinical Excellence, Nicol, Nicol, Oberhelman, O’Grady, Peter, Peter Mwaba, Peter S. Kim, Rifat Atun, Rose, Ruth McNerney, S. Bertel Squire, Samana Schwank, Sester, Shah, Soumya Swaminathan, Squire, Squire, Steingart, Steingart, Steingart, Steve Lawn, Storla, Temple, Theron, Timothy D. Mchugh, Treatment Action Group, Tully, Vadwai, Van Rie, van Wyk, Wallis, Walzl, Weyer, Wilson, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, Wright, Wright, Zar, Ziad Memish, Zumla, Zumla   +118 more
core   +2 more sources

INF-gamma Release ELISpot Assay

Bio-Protocol, 2012
IFN-γ (Interferon-gamma) is produced mainly by activated T cells and NK cells. Production of IFN-γ (Interferon-gamma) by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-γ (Interferon-
Huagang Zhang
doaj   +1 more source

Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level [PDF]

, 2008
Interleukin (IL)-18, formerly known as interferon (IFN)-γ-inducing factor, is a crucial mediator of host defence and inflammation. Control of IL-18 bioactivity by its endogenous antagonist IL-18 binding protein (IL-18BP) is a major objective of ...
Bachmann, Malte, Mühl, Heiko, Paulukat, Jens, Pfeilschifter, Josef Martin   +3 more
core   +1 more source

[Interferon-gamma release assays in tuberculosis diagnostics]

Der Internist, 2007
Two years ago, CE certified interferon-gamma release assays (IGRA) were launched on the German market (QuantiFERON-TB Gold In-Tube and T-SPOT-TB). Since this time, a multitude of studies have analysed these assays. Guidelines have been elaborated by national expert committees of England, the USA and Switzerland.
Hoffmann, H, Loytved, G, Bodmer, T
openaire   +3 more sources

Diagnostic Performance of a Novel CXCL10 mRNA Release Assay for Mycobacterium tuberculosis Infection

Frontiers in Microbiology, 2022
One-fourth of the world’s population has been infected with Mycobacterium tuberculosis (M.tb). Although interferon-gamma release assays (IGRAs) have been shown to be valid methods for identifying M.tb infection and auxiliary methods for diagnosis of ...
Liping Pan, Mailing Huang, Hongyan Jia, Guofang Deng, Yu Chen, Rongrong Wei, Mingxia Zhang, Xin Li, Qi Sun, Mutong Fang, Pengfei Ren, Aiying Xing, Qi Chen, Xinxin Li, Boping Du, Tao Chen, Mengqiu Gao, Zongde Zhang   +17 more
doaj   +1 more source

Enhancement of experimental metastasis by tumor necrosis factor [PDF]

, 1993
The influence of endogenous and exogenous tumor necrosis factor (TNF) on metastasis was investigated in an experimental fibrosarcoma metastasis model.
Echtenacher, Bernd, Falk, Werner, Männel, Daniela N., Orosz, P., Rüschoff, J., Weber, D.   +5 more
core   +2 more sources

Hemodialysis acutely altered interferon-gamma release assay test result and immune cell profile

Journal of Microbiology, Immunology and Infection, 2022
Patients receiving hemodialysis (HD) are at risk of TB development. IGRA-positive patients showed significant decrease in quantitative IGRA result with alterations in CD3+CD4+CD45RO+, NK cell, and monocyte subsets immediately upon HD procedure.
Denise Utami Putri, Chia-Ling Chen, Cheng-Hui Wang, Yuh-Mou Sue, Po-Chun Tseng, Chiou-Feng Lin, Ching-Wen Tsai, Yi-Jun Liu, Chih-Hsin Lee   +8 more
doaj   +1 more source