Results 21 to 30 of about 54,693 (255)

The evolution and role of interferon gamma release assays (IGRAs) in moderate and low income settings.

Sri Lankan Journal of Infectious Diseases, 2014
The interferon gamma release assays have been extensively evaluated in the diagnosis of latent tuberculosis infection as well as in diagnosis of active pulmonary and extra-pulmonary tuberculosis since their introduction just over a decade ago.
C N Ratnatunga
doaj   +1 more source

INF-gamma Release ELISpot Assay

Bio-Protocol, 2012
IFN-γ (Interferon-gamma) is produced mainly by activated T cells and NK cells. Production of IFN-γ (Interferon-gamma) by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-γ (Interferon-
Huagang Zhang
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Diagnostic Utility of Interferon-Gamma Release Assay in Tuberculous Lymphadenitis [PDF]

Chinese Medical Sciences Journal, 2019
Objective The aim of this study was to evaluate the diagnostic performance of T-SPOT.TB for tuberculous lymphadenitis. Methods Suspected tuberculous lymphadenitis patients between September 2010 and September 2018 who had both peripheral blood T-SPOT.TB test and lymph node biopsy were retrospectively enrolled in this study.
Xin-Chao, Liu, Su-Su, Ye, Wen-Ze, Wang, Yue-Qiu, Zhang, Li-Fan, Zhang, Xiao-Cheng, Pan, Zi-Yue, Zhou, Miao-Yan, Zhang, Jiang-Hao, Liu, Zhi-Yong, Liang, Xiao-Qing, Liu   +10 more
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Diagnostic Performance of a Novel CXCL10 mRNA Release Assay for Mycobacterium tuberculosis Infection

Frontiers in Microbiology, 2022
One-fourth of the world’s population has been infected with Mycobacterium tuberculosis (M.tb). Although interferon-gamma release assays (IGRAs) have been shown to be valid methods for identifying M.tb infection and auxiliary methods for diagnosis of ...
Liping Pan, Mailing Huang, Hongyan Jia, Guofang Deng, Yu Chen, Rongrong Wei, Mingxia Zhang, Xin Li, Qi Sun, Mutong Fang, Pengfei Ren, Aiying Xing, Qi Chen, Xinxin Li, Boping Du, Tao Chen, Mengqiu Gao, Zongde Zhang   +17 more
doaj   +1 more source

Hemodialysis acutely altered interferon-gamma release assay test result and immune cell profile

Journal of Microbiology, Immunology and Infection, 2022
Patients receiving hemodialysis (HD) are at risk of TB development. IGRA-positive patients showed significant decrease in quantitative IGRA result with alterations in CD3+CD4+CD45RO+, NK cell, and monocyte subsets immediately upon HD procedure.
Denise Utami Putri, Chia-Ling Chen, Cheng-Hui Wang, Yuh-Mou Sue, Po-Chun Tseng, Chiou-Feng Lin, Ching-Wen Tsai, Yi-Jun Liu, Chih-Hsin Lee   +8 more
doaj   +1 more source

Interferon-Gamma Release Assay is Not Appropriate for the Diagnosis of Active Tuberculosis in High-Burden Tuberculosis Settings: A Retrospective Multicenter Investigation

Chinese Medical Journal, 2018
Background: Interferon-gamma release assay (IGRA) has been used in latent tuberculosis (TB) infection and TB diagnosis, but the results from different high TB-endemic countries are different.
Wan-Li Kang, Gui-Rong Wang, Mei-Ying Wu, Kun-Yun Yang, A Er-Tai, Shu-Cai Wu, Shu-Jun Geng, Zhi-Hui Li, Ming-Wu Li, Liang Li, Shen-Jie Tang   +10 more
doaj   +1 more source

Frequency of hypovitaminosis d in patients with uveitis presenting at a tertiary care hospital in a low-middle-income country

Journal of the Pakistan Medical Association
Objective: To determine the frequency of hypovitaminosis D in patients with uveitis, and to analyse its association with gender and interferon-gamma release assay status. Method: The retrospective, cross-sectional study was conducted in September 2021
Sehrish Nizar Ali Momin, Muhammad Bilal Malik, Haroon Tayyab, Muhammad Irfan, Muhammad Abdul Rehman Siddiqui   +4 more
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Performance of an interferon-γ release assay-based test for cell-mediated immunity to SARS-CoV-2

Frontiers in Immunology, 2023
In search for immunological correlates of protection against acute coronavirus disease 2019 (COVID-19) there is a need for high through-put assays for cell-mediated immunity (CMI) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Luís Fonseca Brito, Luís Fonseca Brito, Silvia Tödter, Julian Kottlau, Kathrin Cermann, Anthea Spier, Elina Petersen, Elina Petersen, Ines Schäfer, Ines Schäfer, Raphael Twerenbold, Raphael Twerenbold, Raphael Twerenbold, Martin Aepfelbacher, Marc Lütgehetmann, Felix R. Stahl, Felix R. Stahl   +16 more
doaj   +1 more source

Interferon-gamma release assays in tuberculous uveitis: a comprehensive review

International Journal of Ophthalmology, 2022
Tuberculous uveitis (TBU) comprises a broad clinical spectrum of ocular manifestations, making its diagnosis challenging. Ophthalmologists usually require evidence from investigations to confirm or support a clinical diagnosis of TBU. Since direct isolation of the causative organism from ocular specimens has limitations owing to the small volume of the
Usanee Tungsattayathitthan, Sutasinee Boonsopon, Nattaporn Tesavibul, Tararaj Dharakul, Pitipol Choopong   +4 more
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Interferon-Gamma Release Assay in a Patient with Tuberculosis Verrucosa Cutis [PDF]

Annals of Dermatology, 2015
Dear Editor: A 62-year-old man presented with an annular plaque that had been present for 35 years on his left inner thigh. Physical examination revealed a 7×8 cm annular erythematous plaque with central clearing and hyperpigmentation (Fig. 1). We suspected tinea cruris, granuloma annulare, and erythema annulare centrifugum, and performed a 4-mm ...
Kim, Geon, Jeong, Young-In, Huh, Joon Won, Kim, Eun-Jung, Joh, Ok-Ja   +4 more
openaire   +2 more sources