Results 61 to 70 of about 55,486 (297)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Use of QuantiFERON-TB Gold to determine the aetiology of idiopathic erythema induratum: A case report

SAGE Open Medical Case Reports, 2018
Although rare, erythema induratum is the most common entity presenting as lobular panniculitis with vasculitis. It is usually caused by a hypersensitivity reaction to Mycobacterium tuberculosis , although other aetiologies have been reported.
Alisa Brandon, Asfandyar Mufti, R. Garry Sibbald   +2 more
doaj   +1 more source

Early diagnosis of miliary tuberculosis in a hemodialysis patient by combining two interferon-γ-release assays: a case report

BMC Nephrology, 2020
Background Patients with end-stage renal disease undergoing chronic hemodialysis (HD) are at high risk to develop tuberculosis (TB) associated with a high mortality rate.
Florence Bonkain, Dieter De Clerck, Violette Dirix, Mahavir Singh, Camille Locht, Françoise Mascart, Véronique Corbière   +6 more
doaj   +1 more source

Accuracy of the interferon-gamma release assay for the diagnosis of tuberculous pleurisy: an updated meta-analysis [PDF]

PeerJ, 2015
Background and Objectives. The best method for diagnosing tuberculous pleurisy (TP) remains controversial. Since a growing number of publications focus on the interferon-gamma release assay (IGRA), we meta-analyzed the available evidence on the overall ...
Cai-Shuang Pang, Yong-Chun Shen, Pan-Wen Tian, Jing Zhu, Mei Feng, Chun Wan, Fu-Qiang Wen   +6 more
doaj   +2 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Interferon Gamma Release Assay Positive Prevalence in the Civilian, Noninstitutionalized U.S. Population, Ages 6+, 2011–2012.

, 2015
a There were no foreign-born study participants with both IGRA positive and HIV positive results* Estimates and 95% CIs may be unreliable because the number of sample positives is < 10§ Estimates and 95% CIs may be unreliable because the RSE > 30 ...
Rachel S. Yelk Woodruff (822128), Philip A. LoBue (338836), Roque Miramontes (421451), Andrew N. Hill (822127), Thomas R. Navin (299862), Lauren A. Lambert (822129), Kenneth G. Castro (822130)   +6 more
core   +1 more source

MANAGEMENT OF LATENT TUBERCULOSIS INFECTION BASED ON T-SPOT.TB ASSAY IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES

Mediterranean Journal of Hematology and Infectious Diseases, 2022
Background and objective: Patients with latent tuberculosis infection (LTBI) receiving chemotherapy for hematological malignancy (HM) are at high risk of developing active tuberculosis (TB) infection.
Emrah Kiliacaslan, Kadir Canoglu
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Distribution of tuberculin skin test (TST) and interferon gamma release assay (IGRA) results in household contacts at baseline and six weeks.

, 2015
Distribution of tuberculin skin test (TST) and interferon gamma release assay (IGRA) results in household contacts at baseline and six weeks.
Laura F. White (298306), Irene Ayakaka (121859), Francis Mumbowa (227426), Olive Mbabazi (455493), Bruce Kirenga (455274), Martin Ssebidandi (798454), Soyeon Kim (533382), Stephanie Moine (273964), Kevin P. Fennelly (798455), Edward C. Jones-López (227412), Christina S. Thornton (424014), Alphonse Okwera (227454), Moses Joloba (230166), Gerald Mboowa (770601)   +13 more
core   +1 more source

INTERFERON GAMMA RELEASE ASSAY AMONG TUBERCULOSIS CULTURE POSITIVE AND NEGATIVE CASES TO DETERMINE CUT OFF VALUE

Pakistan Armed Forces Medical Journal, 2019
Objective: To determine cut off value of Interferon Gamma Release Assay (IGRA) among Tuberculosis (TB) suspected patients and to compare median Interferon Gamma Release Assay value for Tuberculosis culture positive and culture negative patients. Study
Nauman Akbar, Aamer Ikran, Gohar Zaman, Luqman Satti, Muhammad Yasir Rafiq, Muhammad Rizwan   +5 more
doaj