Results 81 to 90 of about 55,486 (297)
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh +7 more
wiley +1 more source
Early detection of perinatal tuberculosis using a whole blood interferon-gamma release assay.
C1 - Journal Articles RefereedBACKGROUND: The diagnosis of perinatal tuberculosis (TB) is problematic because of its nonspecific presentation, the difficulty of obtaining microbiological confirmation, and the unreliability of the tuberculin skin test ...
Connell, T, Curtis, N, Bar-Zeev, N
core +1 more source
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano +11 more
wiley +1 more source
Interferon-gamma release assay and tuberculin skin test positivity (n = 266).
Interferon-gamma release assay and tuberculin skin test positivity (n = 266).
Philip C. Hill (11070347) +10 more
core +1 more source
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan +10 more
wiley +1 more source
Kaplan-Meier curve of HIV-infected patients who developed active tuberculosis disease by interferon-gamma release assay (IGRA) status, excluding 31 subjects with indeterminate results (N = 741).
Hsi-Hsun Lin (473561) +11 more
core +1 more source
Challenges of Loss to Follow-up in Tuberculosis Research. [PDF]
In studies evaluating methods for diagnosing tuberculosis (TB), follow-up to verify the presence or absence of active TB is crucial and high dropout rates may significantly affect the validity of the results.
Michala V Rose +18 more
core +1 more source
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu +13 more
wiley +1 more source
A Review on Immunological Diagnosis Methods of Tuberculosis Infection
Tuberculosis (TB) is a leading cause of mortality and morbidity in the world and this infection is a major public health challenge. TB control is largely dependent on the early diagnosis and managements of suspected cases. Today, for laboratory diagnosis
M Jafari, R Mansouri
doaj
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source

