Results 91 to 100 of about 116,104 (295)

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

A Review on Immunological Diagnosis Methods of Tuberculosis Infection

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2017
Tuberculosis (TB) is a leading cause of mortality and morbidity in the world and this infection is a major public health challenge. TB control is largely dependent on the early diagnosis and managements of suspected cases. Today, for laboratory diagnosis
M Jafari, R Mansouri
doaj  

Ontology-based knowledge representation of experiment metadata in biological data mining [PDF]

, 2009
According to the PubMed resource from the U.S. National Library of Medicine, over 750,000 scientific articles have been published in the ~5000 biomedical journals worldwide in the year 2007 alone.
Burke, Squires, Carl, Dahlke, Hagler, Herb, Herb, Hagler, Jamie, Lee, Jeff, Wiser, Jennifer, Cai, Karp, David, Megan, Kong, Patrick, Dunn, Richard, Scheuermann, Smith, Barry, Yu, Qian   +12 more
core   +1 more source

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

Uloga testova otpuštanja interferona gama u nadzoru nad tuberkulozom [PDF]

, 2012
Tuberculosis is still one of the major global public health threats. Countries with low incidence must focus on exhausting the reservoir of future cases by preventing reactivation.
A Detjen, A Dyrhol-Riise, A Jurčev-Savičević, A Lalvani, A Mandalakas, A Naseer, A Nienhaus, A Pooran, A Seidler, A Veerapathran, A Zwerling, Anamarija Jurčev-Savičević, B Bergamini, B Linas, C Baker, C Denkinger, C Lange, C Lange, D Dosanjh, D Goletti, D Menzies, D Tripodi, E Bruzzese, E Kim, F Piana, F Ringshausen, G Mazurek, H Igari, H Rieder, I Pavić, Ivan Gudelj, J Broekmans, J Choi, J Lighter, J Torres Costa, J Torres Costa, K Ewer, K Higuchi, Kornelija Miše, M Madariaga, M Pai, M Pai, M Pai, M Pai, M Pai, M Pai, M Pai, M Sester, N Harada, R Diel, R Diel, R Diel, R Diel, R Diel, R Diel, R Van Zyl-Smit, S Lee, S Perry, T Connell, T. Mori, U Mack, Vera Katalinić-Janković, Y Kobashi   +62 more
core   +2 more sources

Diagnostic utility of interferon-gamma release assay in extrapulmonary tuberculosis

Diagnostic Microbiology and Infectious Disease, 2015
Early diagnosis of extrapulmonary tuberculosis (EP-TB) is essential. However, diagnosis of EP-TB is difficult. We evaluated the diagnostic utility of an interferon-gamma release assay (IGRA) in diagnosing active EP-TB among suspected patients in Korea.
Jung Ar, Shin, Yoon Soo, Chang, Hyung Jung, Kim, Chul Min, Ahn, Min Kwang, Byun   +4 more
openaire   +3 more sources

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

Advanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon, Sein Kim, Hyun‐Young Kim, Duck Cho, Sungsu Park, Seohyun Kim, Aram J. Chung   +6 more
wiley   +1 more source

QuantiFERON-TB gold in-tube implementation for latent tuberculosis diagnosis in a public health clinic: a cost-effectiveness analysis

BMC Infectious Diseases, 2012
Background The tuberculin skin test (TST) has limitations for latent tuberculosis infection (LTBI) diagnosis in low-prevalence settings. Previously, all TST-positive individuals referred from the community to Baltimore City Health Department (BCHD) were ...
Shah Maunank, Miele Kathryn, Choi Howard, DiPietro Danielle, Martins-Evora Maria, Marsiglia Vincent, Dorman Susan   +6 more
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source