Dynamics of interferon-gamma release assay and cytokine profiles in blood and respiratory tract specimens from mice with tuberculosis and the effect of therapy [PDF]
There are limitations on diagnostic methods to differentiate between active and latent tuberculosis (TB), and the prediction of latent progression to TB disease is yet complex.
C Jafari +22 more
core +4 more sources
Prior to immunosuppression, rheumatology patients are routinely screened for latent tuberculosis infection (LTBI) using Interferon-Gamma Release Assays (IGRA).
Shamma Ahmad Al Nokhatha +5 more
doaj +1 more source
A New Scientific Paradigm as a key to Building a Community with a Common Future for Humanity
The major idea of this article is that for a scientifically based understanding of possible future for humanity we need a new knowledge of regularities for its development.
Valentina M. Bondarenko
doaj
Negative Effect of Smoking on the Performance of the QuantiFERON TB Gold in Tube Test. [PDF]
False negative and indeterminate Interferon Gamma Release Assay (IGRA) results are a well documented problem. Cigarette smoking is known to increase the risk of tuberculosis (TB) and to impair Interferon-gamma (IFN-γ) responses to antigenic challenge ...
A Cattamanchi +43 more
core +1 more source
The aim of this study was to evaluate the diagnostic accuracy of the IGRA, TST, and TBST by combining diagnostic test accuracy (DTA) analysis and network meta-analysis (NMA) to increase the reliability and accuracy of diagnostic methods and promote the ...
Li Peng +14 more
semanticscholar +1 more source
Feasibility, acceptability, and cost of tuberculosis testing by whole-blood interferon-gamma assay
Background The whole-blood interferon-gamma release assay (IGRA) is recommended in some settings as an alternative to the tuberculin skin test (TST).
Wong Ernest +5 more
doaj +1 more source
Concordance between tuberculin skin test and interferon-gamma release assay for latent tuberculosis screening in inflammatory bowel disease [PDF]
Background/Aims Latent tuberculosis screening is mandatory prior to initiating anti-tumor necrosis factor (anti-TNF) medications. Guidelines recommend interferon-gamma release assays (IGRA) as first line screening method for the general population ...
Saad Alrajhi +6 more
doaj +1 more source
Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]
Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick +12 more
core +1 more source
Usefulness of interferon-γ release assay for the diagnosis of latent tuberculosis infection in young children [PDF]
PurposeLatent tuberculosis infection (LTBI) in young children may progress to severe active tuberculosis (TB) disease and serve as a reservoir for future transmission of TB disease.
Ki Wook Yun +4 more
doaj +1 more source
Setting: Patients HIV+ attending in a reference clinic, Southern Brazil. Objective: To compare the interferon-gamma-release assay (IGRA – QuantiFERON® TB Gold In-Tube) with the tuberculin skin test (TST – PPD-Rt 23) for latent tuberculosis infection ...
Gislene Maria Botão Kussen +3 more
doaj +1 more source

