Results 1 to 10 of about 2,610,317 (379)
IL-4 Inhibits IL-1β-Induced Depressive-Like Behavior and Central Neurotransmitter Alterations [PDF]
Mediators of Inflammation, 2015 It has been known that activation of the central innate immune system or exposure to stress can disrupt balance of anti-/proinflammatory cytokines. The aim of the present study was to investigate the role of pro- and anti-inflammatory cytokines in the ...
Hyun-Jung Park +5 more
doaj +5 more sources
Neurotropin suppresses inflammatory cytokine expression and cell death through suppression of NF-κB and JNK in hepatocytes. [PDF]
PLoS ONE, 2014 Inflammatory response and cell death in hepatocytes are hallmarks of chronic liver disease, and, therefore, can be effective therapeutic targets. Neurotropin® (NTP) is a drug widely used in Japan and China to treat chronic pain.
Liang, Shuang +6 more
core +14 more sources
PLoS ONE, 2023 Interleukin-1β (IL-1β) is one of the most potent pro-inflammatory cytokines implicated in a wide range of autoinflammatory, autoimmune, infectious, and degenerative diseases.
Hae-Ri Lee +8 more
doaj +2 more sources
Serum IL–1β, IL–2, IL–6, and IL–8 levels in schizophrenia subtypes
Psychiatry and Clinical Psychopharmacology, 2021 Objective: The cytokines are considered to be an important topic in immunological studies of schizophrenia. In this clinical study IL-1β, IL-2, IL-6, and IL-8 levels were compared among schizophrenia subtypes and a control group.
Murat Kuloglu +4 more
doaj +1 more source
IL-1β and the Intestinal Epithelial Tight Junction Barrier
Frontiers in Immunology, 2021 The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of contents from the intestinal lumen into the intestinal tissue and systemic circulation.
L. Kaminsky, Rana Al-Sadi, T. Ma
semanticscholar +1 more source
PLoS ONE, 2021 In autoimmune diseases, fibroblasts produce and secrete various cytokines and act as sentinel immune cells during inflammatory states. However, the contribution of sentinel immune cells (i.e.
Atsuto Naruke +9 more
doaj +2 more sources
Alzheimer's & Dementia, 2021 Neuroinflammation contributes to Alzheimer's disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular contributors to this vulnerability require elucidation.
A. Lopez-Rodriguez +15 more
semanticscholar +1 more source
Inhibition of the NLRP3/IL‐1β axis protects against sepsis‐induced cardiomyopathy
Journal of Cachexia, Sarcopenia and Muscle, 2021 Septic cardiomyopathy worsens the prognosis of critically ill patients. Clinical data suggest that interleukin‐1β (IL‐1β), activated by the NLRP3 inflammasome, compromises cardiac function.
Katharina Busch +20 more
semanticscholar +1 more source
IL-1β is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1β autostimulation. [PDF]
PLoS ONE, 2012 Many molecular and cellular abnormalities detected in the diabetic retina support a role for IL-1β-driven neuroinflammation in the pathogenesis of diabetic retinopathy.
Yang Liu +2 more
doaj +1 more source
Nature Communications, 2021 Interleukin-1β (IL-1β) is activated by inflammasome-associated caspase-1 in rare autoinflammatory conditions and in a variety of other inflammatory diseases.
S. Vijayaraj +15 more
semanticscholar +1 more source