Results 91 to 100 of about 2,610,317 (379)
Mediators of Inflammation, 2005 We used a mouse fetal skin dendritic cell line (FSDC) to study the effect of the strong allergen 2,4-dinitrofluorobenzene (DNFB) on interleukin (IL)-1β release and IL-1β receptor immunoreactivity.
Teresa J. Matos +4 more
doaj +1 more source
Neurología, 2017 Resumen: Introducción: La interleucina 1β (IL-1β) aumenta la muerte neuronal necrótica debido al estado epiléptico (EE) en el área CA1 del hipocampo de ratas en desarrollo; sin embargo, se desconoce si ejerce un efecto similar en el giro dentado (GD ...
C. Rincón-López +5 more
doaj +1 more source
Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production. [PDF]
, 2006 Inhibition of neuronal cyclooxygenase-2 (COX-2) and hence prostaglandin E2 (PGE2) synthesis by non-steroidal anti-inflammatory drugs has been suggested to protect neuronal cells in a variety of pathophysiological situations including Alzheimer's disease ...
Akundi, Ravi S. +7 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Inflammation and immunosuppression are dominant features of cancer progression. In the tumor microenvironment, macrophages produce interleukin-1β (IL-1β), which subsequently recruits myeloid cells from the bone marrow.
Irena Kaplanov +8 more
semanticscholar +1 more source
, 2016 The expression of MMP-13 mRNA level increased in five OA patientsâ articular cartilage tissues. Quantitative reverse transcription-polymerase chain reaction analysis of the matrix metalloproteinase 13 (MMP-13) in articular cartilage tissues from five patients with OA. Figure S2.
Yujie Liang +8 more
openaire +1 more source
Glibenclamide inhibits NLRP3 inflammasome-mediated IL-1β secretion in human trophoblasts
Journal of Pharmacological Sciences, 2017 Infection-associated pregnancy complications cause premature delivery. Caspase-1 is involved in the maturation of interleukin (IL)-1β, which is activated by the NLRP3 inflammasome. To characterize the significance of the NLRP3 inflammasome pathway in the placenta, the effects of activators and inhibitors on NLRP3-related molecules were examined using ...
Kazuhiro Tamura +6 more
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Frontiers in Immunology, 2020 Helicobacter pylori is a gram-negative, microaerophilic, and spiral-shaped bacterium and causes gastrointestinal diseases in human. IL-1β is a representative cytokine produced in innate immune cells and is considered to be a key factor in the development
Ah-Ra Jang +12 more
doaj +1 more source
Is interleukin-1 beta a culprit in macrophage-adipocyte crosstalk in obesity? [PDF]
, 2015 Adipose tissue remodeling occurs in obesity, characterized by adipocyte hypertrophy and increased infiltration of macrophages which also shift to a proinflammatory phenotype.
Bing, Chen
core +1 more source
Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance The molecular clock provides an anticipatory mechanism, allowing organisms to prepare and respond to daily changes in the external environment.
James O. Early +17 more
semanticscholar +1 more source