Results 11 to 20 of about 13,602,078 (332)
IL-10 and IL-10 receptor overexpression in oral giant cell lesions [PDF]
Medicina Oral Patología Oral y Cirugia Bucal, 2011 Central giant cell lesions (CGCL) and peripheral giant cell lesions (PGCL) occur in the jaws and contain osteoclast-like giant cells and mononuclear cells positive for the macrophage marker CD68. The participation of immune-inflammatory mechanisms has been proposed in the lesions development.
Syrio, Nárriman Fátima Lima +5 more
openaire +4 more sources
IL-10 modulates depressive-like behavior [PDF]
Journal of Psychiatric Research, 2008 The role of pro-inflammatory cytokines in psychiatric disorders has been the focus of great research attention in recent years. Paradoxically, the same is not true for anti-inflammatory cytokines. In the present study, we assessed the behavioral profile of animals with altered expression of the anti-inflammatory cytokine IL-10.
Mesquita, Ana Raquel Marcelino +7 more
openaire +8 more sources
Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core +5 more sources
Emerging Microbes and Infections, 2020 Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly spread across many other countries. While the majority of patients were considered mild, critically ill patients involving respiratory failure and multiple organ ...
Huan Han +13 more
semanticscholar +1 more source
Artificial Intelligence Algorithms for Treatment of Diabetes
Algorithms, 2022 Artificial intelligence (AI) algorithms can provide actionable insights for clinical decision-making and managing chronic diseases. The treatment and management of complex chronic diseases, such as diabetes, stands to benefit from novel AI algorithms ...
Mudassir M. Rashid +5 more
doaj +1 more source
Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]
, 2020 Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea +6 more
core +1 more source
Melatonin attenuates oxidative stress and modulates inflammatory response after experimental burn trauma [PDF]
, 2018 Introduction. Thermal injury activates an inflammatory response. Melatonin possesses anti-oxidant and anti-inflammatory properties. The objective of the present work was to study melatonin effects on the inflammatory response under ...
Atanasova, Milena +3 more
core +6 more sources
JCI Insight, 2020 Background Identifying immune correlates of COVID-19 disease severity is an urgent need for clinical management, vaccine evaluation and drug development.
Yan Zhao +21 more
semanticscholar +1 more source
Virulence, 2020 Toll-like receptors (TLRs) play critical roles in the innate recognition of Mycobacterium tuberculosis (Mtb) by host immune cells. However, controversy has arisen regarding the role of TLR4 in determining the outcomes of Mtb infection.
Jaehun Park +6 more
doaj +1 more source
Gestational Age-Dependent Regulation of Transthyretin in Mice during Pregnancy
Biology, 2023 Our prior studies have shown that protein misfolding and aggregation in the placenta are linked to the development of preeclampsia, a severe pregnancy complication.
Shibin Cheng +3 more
doaj +1 more source